Conserved Protein Domain Family
GH18_narbonin

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cd06544: GH18_narbonin 
Click on image for an interactive view with Cn3D
Narbonin is a plant 2S protein from the globulin fraction of narbon bean (Vicia narbonensis L.) cotyledons with unknown function. Narbonin has a glycosyl hydrolase family 18 (GH18) domain without the conserved catalytic residues and with no known enzymatic activity. Narbonin amounts to up to 3% of the total seed globulins of mature seeds and was thought to be a storage protein but was found to degrade too slowly during germination. This family also includes the VfNOD32 nodulin from Vicia faba.
Statistics
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PSSM-Id: 119361
View PSSM: cd06544
Aligned: 10 rows
Threshold Bit Score: 306.22
Threshold Setting Gi: 730692
Created: 1-Jun-2007
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
putative
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1:putative carbohydrate binding site [chemical binding site]
Evidence:
  • Comment:based on the carbohydrate binding site of the human HCGP-39 and mouse YM1 chitolectins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1            #                              #                                            
1NAR_A         4 IFREYIGvkpnsttlhdFPTEiintetlEFHYILGFAIESYyes-----gkGTGTFEESWDVe--lFGPEKVKNLKRRHP 76
gi 730692      7 VFREFTSddsf--lnqvIPENi-----tEFQVTLSLARDYDgn------nsTNGKFIPYWDTe--kVTPEVIKKFKKKYE 71
gi 147820458 315 LFREYIGaefnnvrftdVPINpn----vEFHFILSFGIDYTtsss---pspTNGKFNIFWDSd--nLGPSQVSSIKSDHS 385
gi 147819531 142 VMMEYIGatgvpvtfddVPIEkd----iDFHFILGFAIDADesg-----naQNGIFSPYWASt---LTPDSVADIKAQHP 209
gi 31432078   30 LFRDYIGaifngvkftdVPINpk----vRFDFILAFIIDYTtetn--pptpTNGKFNIFWQNt--vLTPSAVASIKQSNP 101
gi 31432082    6 LFREYIGaqftgvrfsdVPVNpg----lSFHFILAFAIDYFmatqsskpapANGVFAPYWDTa--nLSPAAVAAAKAAHP 79
gi 116785783   7 LFADYIGalfkgvkfsdVPINpa----vEFHFILAFAIDYTtesg--spvpTDGNFNIFWDTg--nLSPEAVQAIKAQHT 78
gi 168059399   1 MLFDYLGsngvaityndIPVTnt---dvVWVLGLSFAIDMSstg-----atQNGVHSVYWNNaagnLTPAAAKSWRQAHN 72
gi 87240453    4 IFRQYTFdds----feqVFISskf--lkEYQIALTFATDYDqnn-----lpTNGIFRVNWDTt--kVTPESITHFKKQHP 70
gi 1143617     5 VFREYIGvkpdsksladFPQItqt-etiEFHFILGFATEKYnes-----rkGSGNFEESWKDe--fFGPDKVRILKTKHP 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                       # # #            
1NAR_A        77 E----VKVVISIGGrgv--------ntpFDPAEENVWVSNAKESLKLIIQKYsddsgnlIDGIDIHYEHIrsd--epFAT 142
gi 730692     72 PtalrVKVLVSIGNknkqf-----pftiGSDSNSEAWVSEATASLKSIIKTYn------LDGIDVSYEDIaan-eadFVN 139
gi 147820458 386 N----VKVALSLGGdsvgn-----gyayFNPSSVDSWVSNAVSSLTDIIQKYn------LDGIDIDYEHFsad-pdtFAE 449
gi 147819531 210 N----VRALASLSGwslge----kilrwYDPKDPELWISNAFTSLQSLIVTYn------LDGIDIDYENFpkr-nstFPY 274
gi 31432078  102 N----VRVAVSMGGatvnd-----rpvfFNITSVDSWVNNAVESLTGIIQDNn------LDGIDIDYEQFqvd-pdtFTE 165
gi 31432082   80 N----LSVILALGGdtvqnt--gvnatfAPTSSVDAWVRNAADSVSGLIDAYg------LDGVDVDYEHFaag-vdtFVE 146
gi 116785783  79 N----VKVALSLGGdsvds-----qpaeFKPSSVSSWVDNAVSSLSKIIEEYh------LDGIDIDYEHFqan-ndtFAE 142
gi 168059399  73 N----GRIVIAIGGsqlytnsgvynvnwYDPANTTRWLQNAVSSITTIVNTYg------ADGIDIDLERFptgtgstFQS 142
gi 87240453   71 Ev--nIKVYISIGNrgt--------tfpFSPQNNKSWILNATKSLTNIIKNNkdy-nlqVDGIDVLYENIeas-pvdFVE 138
gi 1143617    77 E----VKVVISIGGrgv--------etpFDPAEQNVWVSNAVKSLKLIIQKYknesgnlIDGIDINYEHIkwd--eaFPR 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                          #                             
1NAR_A       143 LMGQLITELKKDddlnINVVSIAPSenn--sshYQKLYNAKKDYINWVDYQFSNqqkpv--stddaFVEIFKSLEKDYhp 218
gi 730692    140 SVGGLVRNLKQNk--lITVASFATSadaannkfYNLLYAEYATFFDTVVFLSWVgftpsranpvasLEEKILAVANEYka 217
gi 147820458 450 CIGQLIKTLKGNg--vISFASIAPFdddqvqshYLALWKSYGQLIDYVNFQFYAydqgt---tvtqFIKYFEEQSSNYag 524
gi 147819531 275 CIGELISLLKNQs--vISVATIAPFnsr--avpYIQLCDGYGDLIDYVNYQFYTdkvs----tpkrYLEAFKLRAKQFdq 346
gi 31432078  166 CVGRLITVLKAKg--vIKFASIAPFgnaevqrhYMALWAKYGAVIDYINFQFYAygast---teaqYVDFFNQQIVNYpg 240
gi 31432082  147 CIGRLLTELKARh--pNIATSIAPFehpvvqryYQPLWRRYAGVIDYVNFQFYGygant---dvatYVMFYDEQAANYpg 221
gi 116785783 143 CIGQLITRLKQSn--aISFASIAPYddqevqshYLALWNKYEHVIDYVNFQFYAydsst---tisqFIGYYNTQASQYsg 217
gi 168059399 143 LIGGLITTLKNNg--vIKFVSVAPGydq--larYTALYNAYSSYIDTVNYQFYGegld----tcakYKARYAQVIQNFps 214
gi 87240453  139 CIGQLIKNLKENg--vIKEASISPSfaln-ndfYFLLYRAYSNQIDWVDYQFQNevvpv--fapnkLVELYDELVLEFyp 213
gi 1143617   143 LIGQLITELKKErdlnIHVVSIAPSenn--assYLNLYNANPDYINLVDYQFSNqlnpv--stddaFVDIYERVVNDYhp 218
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
Feature 1                                                  # #     
1NAR_A       219 -hKVLPGFSTDpldtkhnkitrdiFIGGCTRLVQTf-sLPGVFFWNANDS 266
gi 730692    218 vkAFLVAYSTVaedwan--fsppiFFITLHGLLGNs-aVKGASIKVISDA 264
gi 147820458 525 -xKVLASFISDgsggl---spddgFFTACNRLKSQq-qLHGIFIWSADDS 569
gi 147819531 347 -eKLLPSYEVDgrgi-----qgeaFFDALKLLEKNgidVKGVMIFSADAS 390
gi 31432078  241 -gNILASFTTAattts---vpvetALSACRTLQKEg-kLYGIFIWAADHS 285
gi 31432082  222 -sKLLASFKTGnvtgl---lspeqGIAGAKELQRQg-kLPGLFIWSADSS 266
gi 116785783 218 -gKVLVSFSSAtgaggl--lpengFFEACRMLKQNg-eLKGIFVWCADWS 263
gi 168059399 215 -nIVGLSTQVAgdpnt---itgqtFINCVQDIKTTn-sIAGVYLWNADIS 259
gi 87240453  214 rkKLFAGYSAEnedwat-lspivfFLGGMNILKKRk--GPGISIHYHNYY 260
gi 1143617   219 -rKVLPGFSTDpldhinikitrdiFIGGCTKLKQTs-sLPGVFFWNANDS 266

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