Conserved Protein Domain Family
GH18_3CO4_chitinase

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cd06545: GH18_3CO4_chitinase 
Click on image for an interactive view with Cn3D
The Bacteroides thetaiotaomicron protein represented by pdb structure 3CO4 is an uncharacterized bacterial member of the family 18 glycosyl hydrolases with homologs found in Flavobacterium, Stigmatella, and Pseudomonas.
Statistics
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PSSM-Id: 119362
View PSSM: cd06545
Aligned: 6 rows
Threshold Bit Score: 355.992
Threshold Setting Gi: 32308892
Created: 31-Jul-2008
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
putative active
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:putative active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1           #                          #                                                 
3CO4_A         6 VIGYLALDdwefeslfptIEWKYLTHINASFARVKADGtlnin-------------pvrkrIESVRETAHkh--nVKILI 70
gi 88710913   40 VVGYLPYYrffn---snkIDYCKLTHLNLAFANPDNEGnliv----------------pesINDVVNDARsrngdILIFI 100
gi 146301911  30 VIAYIPNWidlna-fsstIQYSKLTHINIAFENPDANGylsf----------------nsgSNAIINAAHaq--nIKVFV 90
gi 149277365  42 VVGYMFASgdlla-qsagVDFSKISHLNIAFLNPDASGtfgav-------------tglaeLTKKAHDNH-----VKILA 102
gi 115374768 202 VVGYLPNWygsyaswvgrVDFDKLTHVNLAFALGDANGnlqla--------------pasdLATFVNAAHak--gVKVFP 265
gi 32308892   31 VVGYIPSYknmta-vvdsVDLSQLTHINLSFLNPNANGvvtaggdpvcmpgtfggnvtgseLRYVINKAHqa--gVKVLV 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                     # # #                              
3CO4_A        71 SLAKNspgeftt------aindpkARKELIQQIIAFTKEYKLDGFDIDYEEYdnwdk-nfpsLLVFARGLYLAKek-nxL 142
gi 88710913  101 SLAGGslsveqein-wssfvddntKTSTLVDKIIDYVLLNDLDGVDVDLEWShvt-----igYSNFILTLNQALkkedkL 174
gi 146301911  91 SLGGGsvseggairdnyfnlitpaNRTAFIQKIYDYVVAHNFDGVDVDLEGPain-----gdYGGFVIALANKLhangkL 165
gi 149277365 103 AFAGGdppaylk------emmkadKRKSLVDGLLNLTRSYNLDGIDVDLEGDfvn-----edYEAFVVELSAALkkenkL 171
gi 115374768 266 SLCGGggdgqia------pfyqpgRVDAFVDHIINYVVTNKMDGIDVDVEAPdrm----gavYDTFIAKLIAKArprglP 335
gi 32308892  108 SVAGGvipscsgd---wqtllspaNRANTVNNLLNFVSSYNLDGLDVDIEGVvltaidnagnYTPFIQALRNGLps-gkL 183
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                   # ##                                                 
3CO4_A       143 XTCAVnsrwlny--gteweqYFDYINLXSYDRGAft--dkPVQHASYDDFVKDLKYWneqcraskskIVGGLPFYGYSWe 218
gi 88710913  175 LTAALpnntrfehindaalaAFDFINIMAYDGTGpwnannPGQHSSYDFAENGIDFWnssqninsdrLTLGVPFYGYDFt 254
gi 146301911 166 ISAALsegygganvpsstfaAYDWINIMAYDATGpwapgnPGQHSPYSMAVNQFNYWtgrgl-paskAIIGLPFYGYGFg 244
gi 149277365 172 MTAAVatwnsaa-ysdkalaLFDLINIMAYDHTGpwrkdqPGPHSAYEDAVLDFDHWqvtrklpaekLILGLPFYGYGFg 250
gi 115374768 336 VTAAVsqwmqhg-msdttlrSFDFITIMSYDNTGtw--tgPGDHSSYAQAVTALNFYtnkgv-ardrIVLGLPFYGYCWg 411
gi 32308892  184 LTSATasynggm-vptsslpYFDFVNIMSYDAVGpswgvsGNEHSSYAQAQSDIATWkargl-skdkLVLGVPFYGYGFg 261
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                     #                  
3CO4_A       219 eslqgavddvrgirysg-ilkhlgneaadkdnigktYYNGRPTIANKCKFIKEndYAGVXIWQLFQDAhn--dnYDLKLI 295
gi 88710913  255 nqevvsftygqmie--------estefadldestqrYYNGRSTIERKVELAVKr-TGGIMIWELGQDSfd--qySLLNTI 323
gi 146301911 245 asanqgisyaniva-------qypgaenldqvgntiYYNGIPTIKQKTTFAVQn-AGGVMIWELSQDAtg--akSLLTAV 314
gi 149277365 251 pdiaqdmsygalvqty---pgaekedlwvlpgkgtfYYNGIPTIRKKVAFAMKrkAGGVMIWQLLGDAag--eySLLNTI 325
gi 115374768 412 ncgggqtskyilykdllaaypnawnadwinangaqySYNGIATVRSKAALGKQ--YGGIMIWELAGDVstsseqSLLRAL 489
gi 32308892  262 gyassysisdivaqfgs-gaaqqdvignlcsgcsyiTYNGLPTIRAKTQLALQe-GSGVMIWELSQDAsg--snSLLSAI 337

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