Conserved Protein Domain Family
PASTA_pknB

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cd06577: PASTA_pknB 
PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis. PknB is a receptor-like transmembrane protein with an extracellular signal sensor domain (containing multiple PASTA domains) and an intracellular, eukaryotic serine/threonine kinase-like domain. The PASTA domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. The name PASTA is derived from PBP and Serine/Threonine kinase Associated domain.
Statistics
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PSSM-Id: 119328
View PSSM: cd06577
Aligned: 634 rows
Threshold Bit Score: 32.501
Threshold Setting Gi: 81553683
Created: 3-Sep-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 154505948 465 KVPDVTGKSEADAQKQLEDKGfvva----setDYSDSVPQGYVISTNPTAGTEWae---gNTVTMVVS 525
gi 167757023 502 VLGNYVGMDQNKAKEALTKLGfdv-----tikETSSEQAVGTVVEQSLKEGHKVdpdekdRTITLTVS 564
gi 167757023 434 VLEDYTGKKEDVAKKALEKLKfev-----eieYEISSKTKGTVIDQSIEKGTKVdptekdRKIILTVS 496
gi 197338692 537 MVPDVQYKYLKSAQACLRAGGwkwt----vekVDNNTFGDGTVISQKPEPNKDVdkk-nrPTITLRVS 599
gi 81837943  483 KIPDFTFKNIDSVKKCLQAAGwpyd----pkkVDENTFGEGTVMEQYPAAGDDVdpk-dmPDIVLKIS 545
gi 15673869  435 KMKDFVGEKIDEAMATLLKDYgidesqvtqtsVPSDSYPAGTIIKQSPKKGSSFdtk-gsEKITFEVS 501
gi 171742639 648 TLPNYVGQKASEAKSALEKLGfsvk---issqLTLDSSQDKKVASQDPVGGTEVrlr-qeDGTPTTVT 711
gi 29611832  487 QVPDFTFKYIGSVKECFNAAGwqmk----vveVDENTYGEGSVRDQFPTAGTDVdpe-nmPEIQLKVS 549
gi 194342246 498 TAPDFRYKDILSVKACIQAAGwkyk----vveKDEAVYGQDIVLEQNPAALDKVdk--egTEFTLTVS 559
gi 3915344   200 HVKNYVGIYYKDAIASLLSDSinf------diDLANIGDFGNIISQSIPPGTKIne---sDKILITIA 258
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