2QZ7,2QNG


Conserved Protein Domain Family
TerD_like

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cd06974: TerD_like 
Click on image for an interactive view with Cn3D
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD
Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.
Statistics
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PSSM-Id: 132992
View PSSM: cd06974
Aligned: 176 rows
Threshold Bit Score: 49.602
Threshold Setting Gi: 152967253
Created: 8-Jan-2008
Updated: 17-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
 
putative metal
Conserved site includes 3 residues -Click on image for an interactive view with Cn3D
Feature 1:putative metal binding site [ion binding site]
Evidence:
  • Structure:2QZ7: Streptomyces coelicolor A3(2) Sco6318 binds Na+.
    View structure with Cn3D
  • Structure:2QNG: Streptomyces avermitilis Unknown Function Protein Sav2460 binds Ca2+.
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                      # #                                               
2QZ7_A        23 LKRVDVRLKWdpspw----------drpphHLDIIATTYAadaphgrpVYVVQFDKRSPdg----tINXSRhsrtgq--- 85
gi 71423786  313 LSDVRFGVGWng----------------ehDLDAFMVMLDenn---cyLDHLHPKQTRLhsiyphvARHSGdaingf--g 371
gi 163815652 470 TNAVRAFIWWtnmdkcdf----gsyddgrvDIDLSAAIFDenw---nyMEHVSYTNLKSek---ykACHSGdivnggpvd 539
gi 164686752 488 NKKIRLFLHWvent-------------rntDLDLSIVLYDedf---yeIDDVSYMNLKTn-----gCVHSGdvrsap--a 544
gi 199432463 466 KNILRMFIHWig-----------------dDIDLSALFLSedl---ntQSHIAFTNLKDd-----fAWHSGdivnap--g 518
gi 50306737  516 SKVIRLFLYWeniketqg-----aahegrvDVDLSCLQLSdnf---enKGEIAYYNLANg-----aVTHSGdftda---- 578
gi 123438910 341 PKQIKFGLGWsg----------------skDLDSYGFIVSkdy---kvIGYVSGASKSKfs----yIKHMGdaasgs--- 394
gi 219495406 199 FNHVIFDLFWgyps------------hgcdYLDASCLLFSgs----sfVAVIDYDDTSYhs---gvIHHSGdvmdav--- 256
gi 156374428 171 FDQVIFDLYWgyps------------hgqdYLDASVLLYSgn----cfLEVLDFRHQKCnvs-pgaIRHSGdvmddn--- 230
gi 21222139   16 VTHLSIGVSWdptagssggvlgklrrktgtDLDLIAVAMQggd--pvrLAGLDSLDPMGng----sLLHSGdnqtgh--- 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1             #                                                                          
2QZ7_A        86 gfgfvEEXTFELDRlsp---siARVIVGVAIHqdngh---ktfddVSNTGVVVAEGy-----------rELLTDGFerv- 147
gi 71423786  372 ttgdeEFIDLMTYRmpp---evRTIIFGATYVesfgnstgtvksiFDVPKLYLRLQn------------RTAERPNsfe- 435
gi 163815652 540 gdgvsEFLDVDVDSvvr--ygaRYVVYQVYSYtgqt------yadMPHAMFGWMERadvnsgeiyepktVEQKMDLta-- 609
gi 164686752 545 pkggtEYVDINLDKine---qcRYISVCINAYthek------fyeLQECFVGYMDLnkklkt-pynpscVKFKADLts-- 612
gi 199432463 519 pdgasEFIDIDLKKaqe--fgkRYVCMDVRVFcgps------fleHEQCFAGFMLRkepqsgeifepltVRCKFDIts-- 588
gi 50306737  579 tngaaEFIDVKLDDikeafpetRYIAVTVNSYtgq-------kfnTFTAKAGFMIRdnisge-hfepktVEQKFDLls-- 648
gi 123438910 395 edkdaESIVVNLTEvpd---evGTIAIFATYEngt-------flqVQNIYMRVCTTidk-------kekELMYLPVvak- 456
gi 219495406 257 rrqghHTINVKLKEipk---hvTHLFFTLSAWdspn------iskYPNPSLRFFEAsnk--------skQLCRDQMsha- 318
gi 156374428 231 nrlghHTINVTLKSipp---hiNKLFFTLSAWnspn------iskYKNPSLKFYDAsyp--------dkQLCSDSMeha- 292
gi 21222139   87 gdgddETVTVEFARlps---aiTSIVFVAAAYkkgs-----sfqkARNISFKVYDAtg---------gsSEQVADIwpsl 149
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                            
2QZ7_A       148 -agaTAATVAEFTRna--sgAWEFREAVRGFdsd---------pvlFATEXG 187
gi 71423786  436 --vdRWNIHYEVEDeierrkMWKKNKEKNKLekh----------gfVHRTYV 475
gi 163815652 610 --nsTACIPVIFDCvkr-efIWCDMNLSLTGvht---------higGNNVES 649
gi 164686752 613 --etTVSLPFIIDIasn-qiVWCDIEYTSLGdinniitnsnrntmvVKSILD 661
gi 199432463 589 --kgRSADICLFDMktr-emIWIDTMINHGQtansla----nntasSVYIIR 633
gi 50306737  649 --asRFNIPMVLDLyen-tiIWLDLAISQNKiynvnl----hektpLVGSLA 693
gi 123438910 457 -rrqNSLLFGILYRtp--kgSWDLFPAAKLFegkds-----hdigeYCNEFF 500
gi 219495406 319 -aysQAIVMCSVSRkt---gVWKIDSLGTLSrgnak------nyepLKDTIR 360
gi 156374428 293 -aysQAIIMCSLCKid---eVWKVFSLRKISqgnak------nygpIQTTIG 334
gi 21222139  150 lsqdNGCAVAKAVRvg---gTWKLEVVNETGkikq-------gdehALMRFA 191

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