Conserved Protein Domain Family
ALDH_DDALDH

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cd07099: ALDH_DDALDH 
Methylomonas sp. 4,4'-diapolycopene-dialdehyde dehydrogenase-like
The 4,4'-diapolycopene-dialdehyde dehydrogenase (DDALDH) involved in C30 carotenoid synthesis in Methylomonas sp. strain 16a and other similar sequences are present in this CD. DDALDH converts 4,4'-diapolycopene-dialdehyde into 4,4'-diapolycopene-diacid.
Statistics
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PSSM-Id: 143417
View PSSM: cd07099
Aligned: 29 rows
Threshold Bit Score: 486.729
Threshold Setting Gi: 162450436
Created: 14-Jan-2009
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 61398702    7 VSPLDG-RLLGHFPvskpaliQQQLTKSRRAALLWreLPVTERVKRLSPLKKQLLDNLDRLCETIRLSTGKVrteaLLGE 85
gi 162452771  30 YAPATG-ELLGEAPntsaeevRAAVARARRAQEAWgaLPVEERCQRVLRFRDAIVDRTDEIVDLLSRECGKPrheaLLHE 108
gi 198262320   7 HNPATG-EQIGKVAntdleqfPNMLNKARQAQSYWarLSYKERAVYIGRMRRYIMAHADELAKVVSESNGKTrvdaLATE 85
gi 117168602  47 QSPIDG-SRLGEVPlmgdaevHAAVERARLAQRAWaqLPIETRAGRVARVIDAFVERLDDLVDAVVLETGKPrn-dALAE 124
gi 198261979   1 MTQANI-QNLHQSDelneaqaAEVFERARAAARDLrkTTVAERVGELKKVLHRFYEMREEIMDRVCEENGKCrtdaLVAD 79
gi 71425484   15 VNPAIG-KKLEPVErntvgdvKLAVRHARDAQKVWvaLSFAERAKRVEKVKRFLADNAERGASIISQCNGKTrcdaLATE 93
gi 162451257  36 RSPAGG-APLDGVAetelsalATIVASARAAQIAWaeVPIRERAELIARVKNRLLARAEEIATLVHRECGKPieeaALAE 114
gi 162450436  13 ASPLDG-APLCPVRvttadglRDVVRRARQAQAAWaaRPIAERARLLAEAGRCLMGKADEIAAELHRELGKPmadaYGVD 91
gi 109897827  11 INPRTGqEDFELAVfst-eqvASIALHLKQQQVAWweSGLSGRITALEQLASKMAEHKAKLVAALINDTGRAs--eSELE 87
gi 114799768   9 RNPRTGeLDYKIQAaga-eeiAATAQRLRAAQRDWaaLPLTERGAFLLRLADALVKHRTAITAALEIDTGRRr--iAGLE 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                            #                           
gi 61398702   86 IYPVLDLLAYYQKRaprILRTRAVstspfafpaaTARIERRPYGVVAVISPWNYPFHLSVAPLLTALLAGNAVILKPSEL 165
gi 162452771 109 VLVAADMATYFAQIapkALEPHEIklhl--fkhrRSWVHYVPRGVVGVISPWNFPFQLALRDVLAAIVAGNAAVLKPSEV 186
gi 198262320  86 VLPITLACGWYAKNsqkVLRRRWRptgsilffnkLTTIEHLPVGVVGIISPWNYPLSIPFGEVIMGLMAGNAVVLKVAAA 165
gi 117168602 125 WITVVDACHYFTRHagrILADTSItlhh--mkwrGSYVTYVPMGVVAVISPWNLPLAIPMGSVIEALIAGNAVVVKPSEV 202
gi 198261979  80 IMGPLDFMEWLISDaekILADEKAptpla-lmgkKSKIYHEPLGACLLITPWNYPVNNSMIFTMTGFIAGNAIVFKPSEH 158
gi 71425484   94 ILPSVMACEWYAANtarVLAPQKLsrgnmlffnkSNTLQYIPLGVVGIISPWNFPFTIPFSEVIMALMAGNGVVLKVATA 173
gi 162451257 115 VLPNADLIDYWTRSieeLLDDSPValdplaypgkVGRIQRDPRGVVALITPWNYPVAIPLRTIVPALLAGNAVVFKPSEV 194
gi 162450436  92 LGSTPEVFRYYTTRaedFLPAEDVafnpvmfprkKARVERLPHGVVGLIMPWNYPVSIPVHNLVPALLAGNAVVLKPSEH 171
gi 109897827  88 VDVTINAIHRWCKQaptLLAKGESwaae--ipfiELQQDYLPYPLVGVISPWNFPLLLSLVDAIPALLAGSAVLIKPSEV 165
gi 114799768  86 LDGAVAALRGWVAQapgLLPSGWTqgra--mphiRHAPQFVPYALTGVISPWNFPLTLSMIDTIPALLAGSAVIIKPSEV 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                             #          
gi 61398702  166 cLPVGQLIVDLFATLDlpdgLVQWVIGdg-qtGAELIDArpdLVFFTGGLQTGRAVMQRaarHPIPVMLELGGKDTMLVL 244
gi 162452771 187 tPLIALKQKEIWDGAGmpedLFQVVTGyg-ptGAALIDSgiqMLLFTGSVGTGRKVAAAcgeRLIPCVMELGGKAPLIAC 265
gi 198262320 166 tPLVGEAIQRIVEAGQlpegLFQMVYGsggevSSAMLEHgidKLFFTGSVPAGKSIMAAaakTLTPLSLELGGNDPMIVL 245
gi 117168602 203 tPLTLLKAKEVVDAIGiptdLFQVVTGda-rtGAALIDAgvqKVVFTGGVSSGRRVGAAcaeRLIPCVLELGGKAPLIAC 281
gi 198261979 159 tPLKGLLEKIFDASPLik-nSVQVVYGsg-ttAQHLIDQrpaKIFFTGSNRTGHKIMEQaskYLIPLELELGGKDPAIVF 236
gi 71425484  174 tTHVGRFIEECISAGDfppgLFVHVVMqgsdvGPAMLKAgvdKLFFTGSVHIGKQLMAAaaeTLTPVSLELGGNDPMIVL 253
gi 162451257 195 tPRSGALVTSLFDGLLpd-gVLAVAQGgs-dvGAALVGAgvdLVVFTGSVATGKKIAVAcaeRLIPTSLELGGKDSAIVL 272
gi 162450436 172 aARTSAALVGALSDALpe-aLLGLVQGga-eaGAALVEEv-dQIVFVGGVVGGRAVARAaaeRLIPAQIELGGKDAAVVL 248
gi 109897827 166 tSRFVAPFNDVLESVPaldkVLSFVTGag-etGQGVINTv-dSLCFTGSVATGRHVGKAcaeRFIPAFLELGGKDPAVVC 243
gi 114799768 164 tPRFAAPLMAAIAEAGle-dILTLIDGdg-atGAPLIEAv-dVICFTGSVATGRKVAAAaaaKMIPAFLELGGKDPLIVT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                            #  #                                                        
gi 61398702  245 ADADLKRASAAALYGAFCNSGQVCVSVERLYVQQaCFAEFLAMLLKGLSKLKVGhdp----hgDVGVMTSARQIDIVQAH 320
gi 162452771 266 ADADIERTAQAIVFGGFANAGQVCVAVERVYAHReIHDRLLERTVEITKGLNQGdpgk--efvDVGAIIFPPQIDVAERH 343
gi 198262320 246 KDANLERAVNGAIWGGFQNAGQSCGGVERIYVHTsIYSQFVEALCNKTKALRHGvpsa-efnvDIGSLTTANQLKLVQSH 324
gi 117168602 282 DDCEIERTARSIVAGGFINSGQLCISVERVLATEaVHDRLVDRVVALTRELRQGdpra--ddvDVGAIIFAKQMDIAEAH 359
gi 198261979 237 DDVDLKRTVAGVLWGAMTNTGQSCTSIEKLYIQYgIYEDFIAQLKAECEALVVNnadr--gdaDVGAMTARFQTDIVQRH 314
gi 71425484  254 ADASIERAVNCALWAGFQNAGQACASVERIYVHEsIHDEFLSELAAKTRALRHGpdin--fnvDIGAVTTEVQLRTIKEH 331
gi 162451257 273 GDCDLERAARGVLWGAFTNAGQNCAAIERVYVEQaIADRFIARVIALTGQLRAGi--------DVGVMTTARQAEIVRHQ 344
gi 162450436 249 RDADLDRAAHGIAWAGFVNAGQSCAGVERVYVESeVFNAFVGRLVAVAERLRVGddgtapgtvEIGPMATPAQLSRVEAH 328
gi 109897827 244 HDADPALAAKALCWGSMVNAGQSCMSLERVYVHKaIADVFLTTLVQNVNALKHNypdi--qqgQIGPIISAKQVGIVEAQ 321
gi 114799768 241 ATANLEHATDAALRGSVLSTGQACQSIERIYVAAdIHDAFLKRLTEKAAATRLNwpdi--ttgELGPIIFDKQAAILADQ 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 61398702  321 YEDAIaqGAKASGPLlr-----dgNVVQPVVLWDVHHgMKVMREETFGPLLPVMPFSdeAEAIKLANDSDLGLNASIWSQ 395
gi 162452771 344 IKDAVdkGATVKAGGkrap--gqgQFFEPTIIAGCDHaMTVMTEEIFGPVVPFMQVAteEEAIRLANESHLGLNAYVFSE 421
gi 198262320 325 IDEAVkgGAKVAAQSrpvnvsdkgFFHPATVLLDVTHdMTVQREESFGPVITVMPFNteEEVIKWANDSDLALTSSVWTK 404
gi 117168602 360 IKDAVarGALVATGGrrrp--gpgMFFEPTVLTRCTPeMTVMREEIFGPVVPIMKVRdeDEAVRIANDSPLGLHAYVFSR 437
gi 198261979 315 LDDAVdkGAKVLCGGdlid-gkdgKFFLPTVLTDIPDdAALNHEETFGPLLPVYRFNteDEVIDKANDTEFGLSASVWSK 393
gi 71425484  332 VEDAIsrGARIVAQStptgdvssgNFYPATVLTGVTAdMLVMREETFGPVLPVVPFSteEEAIAMANDCRFALTSSVFSR 411
gi 162451257 345 LEAAVegGAEILAGGape---egsLAFPPTVLKVEREdTPLLLEETFGPVLPIIVVKdaEEAIARTNASRFALTTSLWTR 421
gi 162450436 329 VSQAIaaGAQVRCGGar-----rgNCYLPTVLTGVDPsLDLLREETFGPVIPVVAVPdaDAAIRAANESAYGLTGSVWTR 403
gi 109897827 322 LQDAKdkGATILCGGevln-lgggRYCAPTVLTDVTPdMDIVSQETFAAILPVTIVDsdEQGIVMANDSEFGLSAAVFSQ 400
gi 114799768 319 IDDAKakGARVLTGGeiet-hgggLWLKPTVLTNVSHqMKLMTEETFGPLLPVMPYTttEEVIAFANNTEYGLSAAVFAG 397
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
Feature 1                                                                      
gi 61398702  396 diIKAERLAGQLDVGNWAINdvlkNVGHSgLPFGGVKQSG-FGRYHgAEGLLNFSYPVSGLT 456
gi 162452771 422 dtDHARRLAERLQAGSVLVNdvlmNGALPdAPFGGVKQSG-FGRVMgEDGLRQMCDVKHINA 482
gi 198262320 405 dnQRGRAIAARLESGVTTVNdhlyTHGLSeTPWGGWKGSG-IGRTHgPEGLEEMTHAKVVNW 465
gi 117168602 438 dkTRARAVAERIEAGTVMINdvlvSYCAPeAPFGGIKNSG-YGRVHsDDSLRAMCYARHVNH 498
gi 198261979 394 dlERADRVARALEVGAVSINnvmlTEGNPhLPFGGRKSSG-FGRVHgPEGLLGWTASKAIIV 454
gi 71425484  412 nrANAWRVAEKLESGVVSINdhlyEHGMSeVPWGGWKNSG-IGRTHgELGLKEMCHVRCIND 472
gi 162451257 422 gyERAHALARRLRSGVVTINnhgfTGALPaAPWTGAGDSG-YGVTSsPHALAELTRPRFLLE 482
gi 162450436 404 dvARGAALARALRVGVATVNnhmfTAAAPqAVWTGRGISG-YGVQNgPAVVQAMTRPRLLAV 464
gi 109897827 401 nvDYAKQLASQLEAGAVSINdaslTALIHeAEKQSFKYSGlGGSRMgAESIRRFTRKKAYIR 462
gi 114799768 398 tlEEAEAIAIQIDAGAVSLNdaalTGLFHeAEKHSFKLSGlGGSRMgPAGFQRFLRRKALIA 459

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