Conserved Protein Domain Family
ALDH_DDALDH

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cd07099: ALDH_DDALDH 
Methylomonas sp. 4,4'-diapolycopene-dialdehyde dehydrogenase-like
The 4,4'-diapolycopene-dialdehyde dehydrogenase (DDALDH) involved in C30 carotenoid synthesis in Methylomonas sp. strain 16a and other similar sequences are present in this CD. DDALDH converts 4,4'-diapolycopene-dialdehyde into 4,4'-diapolycopene-diacid.
Statistics
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PSSM-Id: 143417
Aligned: 29 rows
Threshold Bit Score: 486.729
Created: 14-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
AAX46184       7 VSPLDG-RLLGHFPvskpaliQQQLTKSRRAALLWreLPVTERVKRLSPLKKQLLDNLDRLCETIRLSTGKVrteaLLGE 85  Methylomonas sp...
YP_001615138  30 YAPATG-ELLGEAPntsaeevRAAVARARRAQEAWgaLPVEERCQRVLRFRDAIVDRTDEIVDLLSRECGKPrheaLLHE 108 Sorangium cellu...
EDY86602       7 HNPATG-EQIGKVAntdleqfPNMLNKARQAQSYWarLSYKERAVYIGRMRRYIMAHADELAKVVSESNGKTrvdaLATE 85  gamma proteobac...
ABK32267      47 QSPIDG-SRLGEVPlmgdaevHAAVERARLAQRAWaqLPIETRAGRVARVIDAFVERLDDLVDAVVLETGKPrn-dALAE 124 Sorangium cellu...
EDY86263       1 MTQANI-QNLHQSDelneaqaAEVFERARAAARDLrkTTVAERVGELKKVLHRFYEMREEIMDRVCEENGKCrtdaLVAD 79  gamma proteobac...
XP_813115     15 VNPAIG-KKLEPVErntvgdvKLAVRHARDAQKVWvaLSFAERAKRVEKVKRFLADNAERGASIISQCNGKTrcdaLATE 93  Trypanosoma cru...
YP_001613624  36 RSPAGG-APLDGVAetelsalATIVASARAAQIAWaeVPIRERAELIARVKNRLLARAEEIATLVHRECGKPieeaALAE 114 Sorangium cellu...
YP_001612803  13 ASPLDG-APLCPVRvttadglRDVVRRARQAQAAWaaRPIAERARLLAEAGRCLMGKADEIAAELHRELGKPmadaYGVD 91  Sorangium cellu...
YP_661082     11 INPRTGqEDFELAVfst-eqvASIALHLKQQQVAWweSGLSGRITALEQLASKMAEHKAKLVAALINDTGRAs--eSELE 87  Pseudoalteromon...
YP_759829      9 RNPRTGeLDYKIQAaga-eeiAATAQRLRAAQRDWaaLPLTERGAFLLRLADALVKHRTAITAALEIDTGRRr--iAGLE 85  Hyphomonas nept...
Feature 1                                                            #                           
AAX46184      86 IYPVLDLLAYYQKRaprILRTRAVstspfafpaaTARIERRPYGVVAVISPWNYPFHLSVAPLLTALLAGNAVILKPSEL 165 Methylomonas sp...
YP_001615138 109 VLVAADMATYFAQIapkALEPHEIklhl--fkhrRSWVHYVPRGVVGVISPWNFPFQLALRDVLAAIVAGNAAVLKPSEV 186 Sorangium cellu...
EDY86602      86 VLPITLACGWYAKNsqkVLRRRWRptgsilffnkLTTIEHLPVGVVGIISPWNYPLSIPFGEVIMGLMAGNAVVLKVAAA 165 gamma proteobac...
ABK32267     125 WITVVDACHYFTRHagrILADTSItlhh--mkwrGSYVTYVPMGVVAVISPWNLPLAIPMGSVIEALIAGNAVVVKPSEV 202 Sorangium cellu...
EDY86263      80 IMGPLDFMEWLISDaekILADEKAptpla-lmgkKSKIYHEPLGACLLITPWNYPVNNSMIFTMTGFIAGNAIVFKPSEH 158 gamma proteobac...
XP_813115     94 ILPSVMACEWYAANtarVLAPQKLsrgnmlffnkSNTLQYIPLGVVGIISPWNFPFTIPFSEVIMALMAGNGVVLKVATA 173 Trypanosoma cru...
YP_001613624 115 VLPNADLIDYWTRSieeLLDDSPValdplaypgkVGRIQRDPRGVVALITPWNYPVAIPLRTIVPALLAGNAVVFKPSEV 194 Sorangium cellu...
YP_001612803  92 LGSTPEVFRYYTTRaedFLPAEDVafnpvmfprkKARVERLPHGVVGLIMPWNYPVSIPVHNLVPALLAGNAVVLKPSEH 171 Sorangium cellu...
YP_661082     88 VDVTINAIHRWCKQaptLLAKGESwaae--ipfiELQQDYLPYPLVGVISPWNFPLLLSLVDAIPALLAGSAVLIKPSEV 165 Pseudoalteromon...
YP_759829     86 LDGAVAALRGWVAQapgLLPSGWTqgra--mphiRHAPQFVPYALTGVISPWNFPLTLSMIDTIPALLAGSAVIIKPSEV 163 Hyphomonas nept...
Feature 1                                                                             #          
AAX46184     166 cLPVGQLIVDLFATLDlpdgLVQWVIGdg-qtGAELIDArpdLVFFTGGLQTGRAVMQRaarHPIPVMLELGGKDTMLVL 244 Methylomonas sp...
YP_001615138 187 tPLIALKQKEIWDGAGmpedLFQVVTGyg-ptGAALIDSgiqMLLFTGSVGTGRKVAAAcgeRLIPCVMELGGKAPLIAC 265 Sorangium cellu...
EDY86602     166 tPLVGEAIQRIVEAGQlpegLFQMVYGsggevSSAMLEHgidKLFFTGSVPAGKSIMAAaakTLTPLSLELGGNDPMIVL 245 gamma proteobac...
ABK32267     203 tPLTLLKAKEVVDAIGiptdLFQVVTGda-rtGAALIDAgvqKVVFTGGVSSGRRVGAAcaeRLIPCVLELGGKAPLIAC 281 Sorangium cellu...
EDY86263     159 tPLKGLLEKIFDASPLik-nSVQVVYGsg-ttAQHLIDQrpaKIFFTGSNRTGHKIMEQaskYLIPLELELGGKDPAIVF 236 gamma proteobac...
XP_813115    174 tTHVGRFIEECISAGDfppgLFVHVVMqgsdvGPAMLKAgvdKLFFTGSVHIGKQLMAAaaeTLTPVSLELGGNDPMIVL 253 Trypanosoma cru...
YP_001613624 195 tPRSGALVTSLFDGLLpd-gVLAVAQGgs-dvGAALVGAgvdLVVFTGSVATGKKIAVAcaeRLIPTSLELGGKDSAIVL 272 Sorangium cellu...
YP_001612803 172 aARTSAALVGALSDALpe-aLLGLVQGga-eaGAALVEEv-dQIVFVGGVVGGRAVARAaaeRLIPAQIELGGKDAAVVL 248 Sorangium cellu...
YP_661082    166 tSRFVAPFNDVLESVPaldkVLSFVTGag-etGQGVINTv-dSLCFTGSVATGRHVGKAcaeRFIPAFLELGGKDPAVVC 243 Pseudoalteromon...
YP_759829    164 tPRFAAPLMAAIAEAGle-dILTLIDGdg-atGAPLIEAv-dVICFTGSVATGRKVAAAaaaKMIPAFLELGGKDPLIVT 240 Hyphomonas nept...
Feature 1                            #  #                                                        
AAX46184     245 ADADLKRASAAALYGAFCNSGQVCVSVERLYVQQaCFAEFLAMLLKGLSKLKVGhdp----hgDVGVMTSARQIDIVQAH 320 Methylomonas sp...
YP_001615138 266 ADADIERTAQAIVFGGFANAGQVCVAVERVYAHReIHDRLLERTVEITKGLNQGdpgk--efvDVGAIIFPPQIDVAERH 343 Sorangium cellu...
EDY86602     246 KDANLERAVNGAIWGGFQNAGQSCGGVERIYVHTsIYSQFVEALCNKTKALRHGvpsa-efnvDIGSLTTANQLKLVQSH 324 gamma proteobac...
ABK32267     282 DDCEIERTARSIVAGGFINSGQLCISVERVLATEaVHDRLVDRVVALTRELRQGdpra--ddvDVGAIIFAKQMDIAEAH 359 Sorangium cellu...
EDY86263     237 DDVDLKRTVAGVLWGAMTNTGQSCTSIEKLYIQYgIYEDFIAQLKAECEALVVNnadr--gdaDVGAMTARFQTDIVQRH 314 gamma proteobac...
XP_813115    254 ADASIERAVNCALWAGFQNAGQACASVERIYVHEsIHDEFLSELAAKTRALRHGpdin--fnvDIGAVTTEVQLRTIKEH 331 Trypanosoma cru...
YP_001613624 273 GDCDLERAARGVLWGAFTNAGQNCAAIERVYVEQaIADRFIARVIALTGQLRAGi--------DVGVMTTARQAEIVRHQ 344 Sorangium cellu...
YP_001612803 249 RDADLDRAAHGIAWAGFVNAGQSCAGVERVYVESeVFNAFVGRLVAVAERLRVGddgtapgtvEIGPMATPAQLSRVEAH 328 Sorangium cellu...
YP_661082    244 HDADPALAAKALCWGSMVNAGQSCMSLERVYVHKaIADVFLTTLVQNVNALKHNypdi--qqgQIGPIISAKQVGIVEAQ 321 Pseudoalteromon...
YP_759829    241 ATANLEHATDAALRGSVLSTGQACQSIERIYVAAdIHDAFLKRLTEKAAATRLNwpdi--ttgELGPIIFDKQAAILADQ 318 Hyphomonas nept...
Feature 1                                                                                        
AAX46184     321 YEDAIaqGAKASGPLlr-----dgNVVQPVVLWDVHHgMKVMREETFGPLLPVMPFSdeAEAIKLANDSDLGLNASIWSQ 395 Methylomonas sp...
YP_001615138 344 IKDAVdkGATVKAGGkrap--gqgQFFEPTIIAGCDHaMTVMTEEIFGPVVPFMQVAteEEAIRLANESHLGLNAYVFSE 421 Sorangium cellu...
EDY86602     325 IDEAVkgGAKVAAQSrpvnvsdkgFFHPATVLLDVTHdMTVQREESFGPVITVMPFNteEEVIKWANDSDLALTSSVWTK 404 gamma proteobac...
ABK32267     360 IKDAVarGALVATGGrrrp--gpgMFFEPTVLTRCTPeMTVMREEIFGPVVPIMKVRdeDEAVRIANDSPLGLHAYVFSR 437 Sorangium cellu...
EDY86263     315 LDDAVdkGAKVLCGGdlid-gkdgKFFLPTVLTDIPDdAALNHEETFGPLLPVYRFNteDEVIDKANDTEFGLSASVWSK 393 gamma proteobac...
XP_813115    332 VEDAIsrGARIVAQStptgdvssgNFYPATVLTGVTAdMLVMREETFGPVLPVVPFSteEEAIAMANDCRFALTSSVFSR 411 Trypanosoma cru...
YP_001613624 345 LEAAVegGAEILAGGape---egsLAFPPTVLKVEREdTPLLLEETFGPVLPIIVVKdaEEAIARTNASRFALTTSLWTR 421 Sorangium cellu...
YP_001612803 329 VSQAIaaGAQVRCGGar-----rgNCYLPTVLTGVDPsLDLLREETFGPVIPVVAVPdaDAAIRAANESAYGLTGSVWTR 403 Sorangium cellu...
YP_661082    322 LQDAKdkGATILCGGevln-lgggRYCAPTVLTDVTPdMDIVSQETFAAILPVTIVDsdEQGIVMANDSEFGLSAAVFSQ 400 Pseudoalteromon...
YP_759829    319 IDDAKakGARVLTGGeiet-hgggLWLKPTVLTNVSHqMKLMTEETFGPLLPVMPYTttEEVIAFANNTEYGLSAAVFAG 397 Hyphomonas nept...
Feature 1                                                                      
AAX46184     396 diIKAERLAGQLDVGNWAINdvlkNVGHSgLPFGGVKQSG-FGRYHgAEGLLNFSYPVSGLT 456 Methylomonas sp. 16a
YP_001615138 422 dtDHARRLAERLQAGSVLVNdvlmNGALPdAPFGGVKQSG-FGRVMgEDGLRQMCDVKHINA 482 Sorangium cellulosum 'So ce 56'
EDY86602     405 dnQRGRAIAARLESGVTTVNdhlyTHGLSeTPWGGWKGSG-IGRTHgPEGLEEMTHAKVVNW 465 gamma proteobacterium HTCC5015
ABK32267     438 dkTRARAVAERIEAGTVMINdvlvSYCAPeAPFGGIKNSG-YGRVHsDDSLRAMCYARHVNH 498 Sorangium cellulosum
EDY86263     394 dlERADRVARALEVGAVSINnvmlTEGNPhLPFGGRKSSG-FGRVHgPEGLLGWTASKAIIV 454 gamma proteobacterium HTCC5015
XP_813115    412 nrANAWRVAEKLESGVVSINdhlyEHGMSeVPWGGWKNSG-IGRTHgELGLKEMCHVRCIND 472 Trypanosoma cruzi strain CL Brener
YP_001613624 422 gyERAHALARRLRSGVVTINnhgfTGALPaAPWTGAGDSG-YGVTSsPHALAELTRPRFLLE 482 Sorangium cellulosum 'So ce 56'
YP_001612803 404 dvARGAALARALRVGVATVNnhmfTAAAPqAVWTGRGISG-YGVQNgPAVVQAMTRPRLLAV 464 Sorangium cellulosum 'So ce 56'
YP_661082    401 nvDYAKQLASQLEAGAVSINdaslTALIHeAEKQSFKYSGlGGSRMgAESIRRFTRKKAYIR 462 Pseudoalteromonas atlantica T6c
YP_759829    398 tlEEAEAIAIQIDAGAVSLNdaalTGLFHeAEKHSFKLSGlGGSRMgPAGFQRFLRRKALIA 459 Hyphomonas neptunium ATCC 15444

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