Conserved Protein Domain Family
ALDH_AAS00426

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cd07109: ALDH_AAS00426 
Uncharacterized Saccharopolyspora spinosa aldehyde dehydrogenase (AAS00426)-like
Uncharacterized aldehyde dehydrogenase of Saccharopolyspora spinosa (AAS00426) and other similar sequences, are present in this CD.
Statistics
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PSSM-Id: 143427
View PSSM: cd07109
Aligned: 23 rows
Threshold Bit Score: 634.658
Threshold Setting Gi: 121611411
Created: 14-Dec-2008
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:
  • None

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 41350164   21 VLDPSTGTLLDRTLRgtgeHVDAAVAAARAASREwa--htPYSERSAILRRIGELIRRDRGEFALLESQDTGKPLaQACA 98
gi 206684504  29 VEDPGNGQHVGDCALageeTLAKALEAARASFERgdltamKPARRGQLMQRIAAEIRGIADEGAELLCRESGKSLsAAHD 108
gi 196250481  23 VFNPANYEPIAQVPRgnseDVNDAVEAARRAFESqqwrnvKPHERGYILLEMAKRIRECKDELARLETLDVGKPLsQSYA 102
gi 86136097   26 VVDPATGTVLAAHALadagDVDRAVQAAKRIHLSgalrdmRPIERGRLVQAMGRYLLDHKDDIARLLTLEQGKPLwEAII 105
gi 26992048   25 IHNPGTTDLVATIAQasvaDAECALQAARRCADSnalnrvRPAQRVTWLLEVAAQIRAITDEGAWVLCQENGKSLrDARD 104
gi 89899790   28 IDNPATGEPIAEVARampaDVDRAVAAARRSFASralldlPPAERGQLMFEVARHLGEMTEEIAKLECLDNGKTLaNGRN 107
gi 87119307   43 IDDPSSAKTFTHVSAaqvsDVELAISAANQAFKQvwk-paKGSARAAILNKAAALLEQKADLFSVVEALDSGKPLaEAQG 121
gi 99080688   40 SFDPGRATAFGDFAAgtavDVDRAVSSAVAGFAIwr--dtAPATRCAVLMEAARLMRAEADWLAVIESLDSGKTLaEAYG 117
gi 118591586  41 SFDPGRGEAFARFTAgtaeDVDQAVQSSRIAFETvwr-dmAPAERSRILLKASRLILENLDLLAVAETLDSGKALqEAEG 119
gi 121611411  42 SFDPGSGRVFAQFAAggevEVDAAVHAAKRALPAws--etAPAERSRVLWAIAQQVRQHADRLALIECLDSGKRLgEAQG 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 41350164   99 DTDVAARYFEYYANTmeaffGHSLPpngdFVAYTRHVPFGVTGHIIPWNYPLQIGCRTIAPAIAVGNCAVVKPAEeaPLS 178
gi 206684504 109 EFEEAAQYFEYYGGMadkieGKSIPlgpdYADYTVYEPYGVSAQIVPWNFPVSIAARSLAPAMAAGNSVIIKSPEldPMA 188
gi 196250481 103 DVEAAARYFEFYGGVadkimGETIPvepgILDYTIREPLGVTAHIIPWNYPIQISSRSAAAAIAAGNAVVMKPAEdaPLT 182
gi 86136097  106 EVEGAALYFEYYGNQastveGRSIPlgagYFDWTEHEPLGVSGQIIPWNYPLEMTARSLSAALATGNACVVKTPEltPLT 185
gi 26992048  105 EFIEAARYFEYYAGMadkieGKSIPlgdgYIDFTVYDPLGVSLQIVPWNFPVSICARSLAPALAAGNAVVIKSPElsPLG 184
gi 89899790  108 DVKLTMRYLQYYGGMadkleGRQIPlgpgVLDYTVHAPFGVSAQIVPWNGPLPVGARSVCCALITGNTVVLKSPEdsPLS 187
gi 87119307  122 DVSSAIATLRYYAGSadkleGNSYPlgqgNFSFSSKEPCGVTAHIIPWNFPLSTTIRGVAPALAAGCTAVVKPAEttPLT 201
gi 99080688  118 DVQGSARLFEYYAGAadkldGRSVNlgndNAAFTLREPVGVTAHIVPWNYPTSTLVRGIAPALAAGCSAVVKPAEttPYT 197
gi 118591586 120 DVRGAARAFEYYAGAcdklqGDSFPlgpnYVGYTVHEPVGVTAQIIPWNFPISTAARGFAPALAAGCTVVAKPAEqtPFT 199
gi 121611411 120 DVRGVIRAFEYYAGAvdkmqGDSFPlgkdYIGFTVEEPIGVAAQIIPWNYPVGTAARGIAPALAAGCTVVAKPAEqtPLS 199
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                          #             
gi 41350164  179 VLKVARTALeaGLPAGVLNVVPGLGaqAGAALAGHAgIDHLSFTGSVPVGAAVAHAAAenVIPVVLELGGKSPNIVFPDa 258
gi 206684504 189 LAMLGVALEraEVPAGTVSILNGIGadLGARLVESPaVDQIVFTGSVPTGQAILRAAAnpVTPALMELGGKSAAVAFEDa 268
gi 196250481 183 TLKLAEFFDelNLPNGIFNVVTGFGheAGAALALHPdIDHVTFTGSVETGIFVMQAAAknVVPVTLELGGKSPNIVFSDc 262
gi 86136097  186 NAWFAHAAEavGLPRGAVNILCGLGheAGAALSAHPdVNQIVFTGSVPTGIAIAKTAAgnVVPCVLELGGKSAAIVHADa 265
gi 26992048  185 LCVLMQAIEraGLPQGAVNLICGRGreVGAYLAGHRdVDQIVFTGSVGTGQSILRSAAehAIPSVMELGGKSAALVFPDa 264
gi 89899790  188 LFKFAEACEkaGVPKGALNIICGYGhdAGAALVAHRdIDHIVFTGSVATGKSVLRSAAerVIPCVMELGGKSAGIVHADa 267
gi 87119307  202 ALMMADIFHaaGLPDGVYNVIPGLGkeAGAALVNHKdVHHITFTGSVATGIGVMQAAAknINSVTLELGGKSPILALADc 281
gi 99080688  198 ALMIAELLIraGLPAGVVNVVTGTGpeAGAPLVRDPrVRHVTFTGSVQTGVGVMQAVApnVTGLTLELGGKSPLVAFADa 277
gi 118591586 200 ALLLAKILHdaGLPAGVCNVVTGTGveTGAPLTAHAdVDHITFTGSVQTGKAVMKAAAdeITRVVLELGGKSPVVVLGDc 279
gi 121611411 200 ALLLAELASaaGLPAGVLNVVTGTGaaAGAALVAHPgIGHITFTGSVATGQRVMRAAAdnVTRVLLELGGKSPLVVLADc 279
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                         #  #                                                           
gi 41350164  259 DLDAAIPVIVKSMLQNAGQTCSAGSRLLVHeeVRDEVLARIDEALRGVriGPGPqd----lDLGPLISAKQRDRVTQMVQ 334
gi 206684504 269 NLDTLMSSLQSGIFYNAGQVCSAMSRVLVHrsIYGEAVERAAALANGLsvGHGLen----pGLTPVISARQLDGIETLTA 344
gi 196250481 263 DKEKALHWIVKSIIQNAGQTCSAGSRLIIEksIKDSFVEALVERFKNMtiGPGIed----vDIGPIISKKQFDIIQNFLS 338
gi 86136097  266 DLEAFEADIRWGIYFNAGQVCSAMSRVIVHesRHAEMLERAEAVARGLsvGPGVerdtfgaNMGAMVSNAQRDHAVQMVA 345
gi 26992048  265 DREQLISSVKSGIFFNAGQVCSAMSRLLVHrsIYDEVVADVVAMAEGLtvGLGQdn----pDHTPVISAAQLEGIEALCR 340
gi 89899790  268 DLERAVKSAARGIFFHAGQICSAASRLLVHrsIYDEFVSLMVKEAEARsvGAGIeg----hDMGPLISARQLDKVEGLCR 343
gi 87119307  282 DLEKTAEGVLWAIFYNAGQICSAGSRLVVDksIHKALVALIVEKTKQLtpAHALen----pNYGAINSAQQLNKIDGFIK 357
gi 99080688  278 DAEKVAEGALWAIFSNAGQICSAGSRLVVHrdLHAQVLERLVKKATTLrfGHGLhn----pDMGALNSERHQAAISGHVE 353
gi 118591586 280 DREQALSGVLGAIYENAGQICSAGSRLVIEksIHADFVAELVKRTKALklGHGLgn----pDVGPVNSAEHLAKVAGFVD 355
gi 121611411 280 DVEQALDGVLGAIYENAGQICSAGSRLIIErkLHGSFMARLLERVGKLglGHGLdq----pDVGPVNSLLHLNRIHEHVA 355
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 41350164  335 RaadsGARQLGGPGQvel--pegGFYFPPTVFTDvdpaqEIAQEEVFGPVLAAMSFGtVDEAIQLANGTQYGLIAAAWTR 412
gi 206684504 345 TarqsGARAASGGARle----reGYFMAPTILADvdpaaRVAQEEIFGPVTCFTPFDtEAEAIAMANGTEFGLVAGVFTR 420
gi 196250481 339 Iae-rEGKILVGGRRvmipgnekGYYVQPTIVDEvdansPLAQEEIFGPVLTVLTFEsEEEAIQMANGTKFGLVTGIWTS 417
gi 86136097  346 AaqdqKAQLVAGGHAln----hvGAFMEPTVLSVap-dmEIAQQEVFGPVLSVMPFRsDAEAIEIANGTDFGLVAGVFTA 420
gi 26992048  341 RaqqqGAVVATGGEAisg---lsGHYMAPTVLRDvtaqmEIAQTEVFGPVLAVIPFDsEEEALAIANGTVFGLVAGVFTQ 417
gi 89899790  344 VgvdeGARLATGGARlpg---rkGYFMAPTVFRDvhpemRIARDEFFGPVVVVIPFDtPEEAITIANGTDYGLAAGVFTR 420
gi 87119307  358 RakerGIQTACGGHKlet--ksgGWFYAPTIMDDvpmddELVQEEIFGPVLTVQVVDgLDEAIEAANCTNFALAAGVYSQ 435
gi 99080688  354 RararGVEILCGGQAttdpatgkGWFFEPTILDAlsaddPAIQQEIFGPVLGVQVFDdEDEALALANGTEFALAAGVYTK 433
gi 118591586 356 RararGADVVTGGAIaadpesgkGWFYQPTIVDSvaagdELAQEEIFGPVLTVQVADdADHALALANDCQYGLVAGVYTS 435
gi 121611411 356 TaaarGNAVLAGGSIaqpanapgGWFYRPTVIEArsaqdPVVQEEIFGPVLVVQQADdLEQAIALANGTDYALVAGIYTR 435
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                    
gi 41350164  413 NLDVAHVMAEeIRAGQVYLNTYGgGGGVEYTFGGFGKSGYGREKGFEALKGFCQTKTIVT 472
gi 206684504 421 DLARAHRVANrLRAGQVFVNEWF-AGGISTPFGGVGKSGFGREKGLEALYNYVRTKNIAI 479
gi 196250481 418 DVKRAHRVAErVQSGQVFINNYGaGGGIQMPFGGYKRSGFGREKGLEALRNYTQLKNIAL 477
gi 86136097  421 DLDRATSAARaLRAGQVFVNEWY-AGGVETPFGGYGKSGHGREKGREALWNYVQTKNVAV 479
gi 26992048  418 DLNRALRCARrLCTGQVFVNEWY-AGGIETPFGGVGLSGFGREKGQEALYSYVRTKNLAV 476
gi 89899790  421 DLSLALWTADrLVAGQVYVNDWW-VGGVETPFGGTKRSGYGREKGQEALLGYVQTKNVGI 479
gi 87119307  436 NIDQALAAAQgIDSGQVTVNNYW-AGGIEVPFGGNKHSGIGREKGLVALDNYCTTKAITL 494
gi 99080688  434 DTSTALRMARrIDAGQVTVNDYW-AGGIELPFGGNRKSGFGREKGLEGVDAYTRAKAITL 492
gi 118591586 436 NFAKAHQLARkIDAGQIYINEYF-AGGIEVPFGGNKKSGFGREKGLEGLKSYCKTKSIAA 494
gi 121611411 436 DITQAYRFARrVDAGQVYINEYF-AGGIEVPFGGNRKSGFGREKGLEGIKSYCKLKSVVA 494

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