Conserved Protein Domain Family
ALDH_AldA_AN0554

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cd07143: ALDH_AldA_AN0554 
Aspergillus nidulans aldehyde dehydrogenase, AldA (AN0554)-like
NAD(P)+-dependent aldehyde dehydrogenase (AldA) of Aspergillus nidulans (locus AN0554), and other similar sequences, are present in this CD.
Statistics
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PSSM-Id: 143461
View PSSM: cd07143
Aligned: 4 rows
Threshold Bit Score: 928.475
Threshold Setting Gi: 146345365
Created: 2-Jan-2009
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
NAD(P) bindingcatalytic
Feature 1:NAD(P) binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 146345365  13 IKYEQPLGLFINNEFVKGVEGKTFq--VINPSNEKVITSVHEatekDVDVAVAAARAAFEGpwr--qvTPSERGILINKL 88
gi 12230028   16 GSTSINTGLFINGEFVDGVKNTTId--VVNPANGKLITKISEateaDIDIAVEAAHKAFETtwg-lncSGSKRGDMLYKL 92
gi 58268384   16 GKVEVPTGIFINGEWASSVDKNAKtidVYNPTTGEVLTKIPEaleaDVNKAVEVAHNAFNNswg-lsvPGFKRGEYLIKI 94
gi 30913454   17 KTYIQPVGLFINNQHVDSVHGGRVk--VYSPSTEKLICEVADadeeDVDIAVKVARAAFQTdapwrkfSSAQRGRCLSRL 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                 ## ##  
gi 146345365  89 ADLMERDIDTLAAIESLDNGKaf-tMAKVDLANSIGCLRYYAGWADKIhGQTIDtnpeTLTYTRHEPVGVCGQIIPWNFP 167
gi 12230028   93 AQLMEKNIDDLSAIEALDNGKtflwAKSVDLSLSISTIKHYAGWADKNfGQVIEtdekKLTYSRHEPIGVVGQIIPWNFP 172
gi 58268384   95 AELMERDLDILASLEALDNGKtfgaAKGFDVIESARTFRYYGGWADKIhGKVIEtsssKLTYTLHEPVGVCGQIIPWNFP 174
gi 30913454   95 ADCIEQNLEYLASIETLDNGKsi-tLARGDVQAAADCFRYYGGWADKDyGQTIEtdikRFAYTRHEPIGVCGQIIPWNFP 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                            #  #                            ##   ##            ####  #  
gi 146345365 168 LLMWSWKIGPAVAAGNTVVLKTAEqTPLSALYAAKLIKeAGFPAGVINVISGFGrtaGAAISSHMdIDKVAFTGSTLVGR 247
gi 12230028  173 LLMLAWKIGPALATGNCIVLKPSEfTPLSALRMCALIQeAGFPPGVVNVVTGYGsttGQAISSHMkIDKVAFTGSTLVGR 252
gi 58268384  175 LLMFSWKIAPALAAGNTVVIKPSElTPLTAMYMTKLFNeAGLPKGVINVVVGYGqtvGNALAGHPaIDKVAFTGSTAVGR 254
gi 30913454  174 FLMCAWKIAPAVACGNTIILKTAElTPLSALCLTKFVPeCGFPPGVINVLSGDGrrcGNAISSHMdIDKVAFTGSTGVGR 253
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        ##              ###                               #                             
gi 146345365 248 TILQAAAkSNLKKVTLELGGKSPNIVFDDADIDNAISWANFGIFFNhGQCCCAGSRILVQegIYDKFVARFKERAQKNkV 327
gi 12230028  253 KVMEAAAkSNLKNVTLELGGKSPVVIFDDADLEQSVNWTAHGLFWNhGQACCAGTRIFVQegIYDKFLQKFTDKIKEIkL 332
gi 58268384  255 KVMEEASkSNIKKVTLELGGKSANIVFEDADFEEAVKYSAQGIFFNhGQTCCAGSRIYVQkpIYEKFVKAFKEQTSKLkV 334
gi 30913454  254 MVMRAAAsSNLKKVTLELGGKSPNIVFNDADLDSAAVWTNYGIFYNsGQVCCAGSRVYVQedVYDEFIKRMVAKAKTLkV 333
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                           # #          
gi 146345365 328 GNPFeqdtFQGPQVSQLQFDRIMEYINHGKkaGATVATGGDRhgneGYFIQPTVFTDvtsdMKIAQEEIFGPVVTIQKFK 407
gi 12230028  333 GDPFglgiDQGPQVSQIQYDRIMSYIESGRaeGATVHVGGERhgneGYFIQPTIFTDttpdMKIVKEEIFGPVGAVIKFK 412
gi 58268384  335 GDPFdpntYQGPQVSQIQAERIMSYVDHGKqeGATVITGGKRcgdkGYFIEPTVFGDvtanMKIVKEEIFGPVVVVSPFE 414
gi 30913454  334 GDPFaedtFQGAQVSKQQYERIVSYIESGIahGAKLEIGGKRhgnlGYFVEPTILSNvtedMAVGKEEIFGPVLAVIKFK 413
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                       #                                     #                          
gi 146345365 408 dEAEAIKIGNSTDYGLAAAVHTKNVNTAIRVSNaLKAGTVWINNYnmISYQAPFGGFKQSGLGRELGSYALENYTQIKTV 487
gi 12230028  413 dGKEVIKQANDSNYGLAAAVFSQDINKAIETAHaFKAGTAWVNCAntIDAGVPFGGYKQSGIGRELGEYALHNYTNVKAV 492
gi 58268384  415 tEEEALEHANDSVYGLASAVFTSNISRATRVASkLKAGTVWINCYneLHPQVPFGGFKQSGLGRELGEYALENYTEIKAV 494
gi 30913454  414 tIEEAIRRGNNSTYGLAAGVHTNNITNAIKVSNaLEAGTVWVNCYnlLHHQIPFGGYKESGIGRELGSYGLTNYTQTKAV 493

                 ....
Feature 1            
gi 146345365 488 HYRL 491
gi 12230028  493 HVNL 496
gi 58268384  495 QINV 498
gi 30913454  494 HINL 497

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