Conserved Protein Domain Family
ALDH_y4uC

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cd07149: ALDH_y4uC 
Uncharacterized ALDH (y4uC) with similarity to Tortula ruralis aldehyde dehydrogenase ALDH21A1
Uncharacterized aldehyde dehydrogenase (ORF name y4uC) with sequence similarity to the moss Tortula ruralis aldehyde dehydrogenase ALDH21A1 (RNP123) believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and similar sequences are included in this CD.
Statistics
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PSSM-Id: 143467
View PSSM: cd07149
Aligned: 26 rows
Threshold Bit Score: 655.05
Threshold Setting Gi: 33597690
Created: 2-Jan-2009
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2494080    58 IAVHSPYDGSLLGsveatdpaDIDRLLATARRGAEISRnLPRHKRASILEGAAQMVESRHDAFAEIIVREAGKtIVQARK 137
gi 91777635   17 QSLTDKYHGNEYGrmavasaaQVTQAVDGALAGFRAST-LSPYERFRILMEAARIVESRMPMLIDLMRDEAGFtHADGEN 95
gi 33597690   31 FPVLDKYTLAPAAevsrasrrQVAQAVSQCKAAADRGA-PAARERAAILRRAAGLLDAYRQDFEAVMMVEGGFtVHDISA 109
gi 119715657  29 LEVRAPYGGELLAriaestpdEVDAAVTLAARTFARNE-LTPHERADILRRTSQLIAQRAEEFAHSVVAEAGKpLRDARA 107
gi 118470929  29 TTLTAPFDGRELAvipv-ggrRDVERAVQAAHNARRTG-LPLDRRLTILEAVAASIAARSEDFARAIALECAKpIKTARA 106
gi 15605756   19 IEVIYPYTRKPIGrvpkgdekDVEKAIERAKEGFKEIFsLTAYERYEILMRAAQLLKERAEEFAKTLVLEVGKtIREART 98
gi 195952919  19 LDVIYPYDNTKIGksyvvndsYVEKAIEKAKIGLKKLSsLSAFEKYEILYKTSELLRKNKEEIARTIVYEVGKtIKEARV 98
gi 149176963  30 IDVINPFDQSVIDtipqgsgdDVLKAVSVLEQGARIMKsMTAYDRSLILQKASELMLERKDDFARTISLEEGKiLAESQV 109
gi 23100694   22 QEIKNPFTGEVIGeqyfaqsdDVEIALATAYKGKKQVKnIPIIERSKILKKAAYLLEENKEKFAKLLSSELGKpLKDTLG 101
gi 15614301   23 IEVIDPGTNHVIAtvpaateaDAKAAIEAAKEGAEIARqMPIHERAAILKRTAEIVTRDRELFAQTIAKEGSKtIREARS 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                             #                          
gi 2494080   138 EVLRCVNTLKLSAEEAKrNAGEIVPFdaytGSEQRQGWFTRDPLGIITAITPYNDPLNLVAHKLGPAIAGGNAVMLKPSN 217
gi 91777635   96 EVRRCVQTFELSAEEGKhLAGELVPMeaaaGVRNRMGFTIRVPRGVVCAITPFNSPLNTLAHKVGPAIAGGNAVVIKPSN 175
gi 33597690  110 EFTRAKVTLELSADEALrLTGSMVPFqaspGAEHKLGFTVRVPVGVVAAITPFNAPLNTVLHKVAPAFAAGNSVVLKPSA 189
gi 119715657 108 EVARAVLTFELCAQEATrLAGEVVPVegtpGSENRRAFTIRRPAGVVCAITPFNGPVNQLSHKVPTAIAAGCTVVVKPAE 187
gi 118470929 107 EVLRAIDTIKFSVAAARtLGSESVPLdataAGAGKVTFTKRVPVGVVAAIAPFNFPLNLVVHKVAPALAVGCPVVLKPAT 186
gi 15605756   99 EVQRAIQTLIFSAEEAKrVNGETFPIdahpNGKGKLGFYIRVPVGIVSAITPFNFPLNLSMHKVAPALAAGNAVILKPSE 178
gi 195952919  99 EVDRAIETFRFSAEEAKrIYGKTYPVdahpNGKSKFGFYIRVPAGIVVAISPFNFPLNLTAHKVGPAIAAGCPVIVKPSE 178
gi 149176963 110 EATRSAEVIRLSGEEARrMTGEMIPLegnaGGQNKLGFTLRIPCGIVAAITPFNFPLNLVCHKVGPAIAAGNAILIKPAS 189
gi 23100694  102 EVDRSIETLELSGEEAKrLHGETIPGssseRGLNTIASIYRVPVGVVAAITPFNAPLNLVCHKVGPAFAGGNVTLLKPAP 181
gi 15614301  103 EVRRCIETLTLSGEEAKrLHGETIPFsqmpGHERRVGYFYRFPIGIIVAITPFNDPLNLVAHKIGPAIAAGNSLIIKPSS 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                             #          
gi 2494080   218 lTPFSAIKLVGALREAGLPEEVITISHGDREl-VTAMIAAReVRMVSFTGGFATGEAISRAAgLKKLAMELGGNAPVIVM 296
gi 91777635  176 vTPLSAVELCKVLIDAGLPANLLALVHGSGSaiGRQLLADPrIAFYAFTGSTQVGREIQQAAgLRGMQLELGSIASTIVC 255
gi 33597690  190 fTPLTSALLARVLLEAGMPPEFLAVVQGEGDdvGTWLLEEQdVAFYTFTGSTRVGRIIQRAAgLRRTQMELGSIASTIVC 269
gi 119715657 188 vTPLSAIKVVQAMLDAGLPPGHVTVVQGRGEtvGQQLLEDPrFAVYSFTGSTAVGAHIRRTVgLRKTLLELGNNSANIVH 267
gi 118470929 187 qTPLSALLLAEVFHEAGLPAGWLNVVCGSGAevGGALATHPdVAYVTFTGSPQVGWGIAEAApKKKVRLELGSNAPLIVD 266
gi 15605756  179 rTPLTPLMLGEILLEAGVPPKALSVIPGYGDv-GKAMTTHPdVRVVSFTGSRKVGDIIARQVgIKKLVLELGSNSAIILH 257
gi 195952919 179 kTPLSPIIMGELLLEAGLPKEAISVLPGYGGl-GKALTTHKdVRVVSFTGSKMVGELIAKQAgIKKLVLELGSNSALVIH 257
gi 149176963 190 dTPLSALKLTELLLEAGLPKEAIACITGPGGeiGRAICTDTrIRKISFTGSYEVGTKICEMAgLKKVTMELGSNSPVIIM 269
gi 23100694  182 qTTLIATAFLQLLFEAGFPKNAIHMLLGGVDv-GQQIVKDErINVISFTGGLVASRNISQIAgIKKTLFELGGNAATIVH 260
gi 15614301  183 fTPLSALRLVKALEEAGLPKKIVQVITGHGSviGPTLTKHRdVRLISFTGGYETGEKIARSAgVKKLAMELGSNSPTIVL 262
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                            #  #                                                        
gi 2494080   297 NDcDFDKAVEGCVSGAFWAaGQNCIGAQRILIQselYGRFRDAFVAATKKLkAGDPLQEdTDVGPMISKQVAERTEAAVN 376
gi 91777635  256 EDaDIDLAIPKIVNAGFRKaGQVCTSVQRLFVArgiADEFIPRFVAAVKATpYGDPADPkTILGPMISVQHAQRAAAWVR 335
gi 33597690  270 ADaDLEAAVPRIANAAFRKaGQVCTSIQRLYVEdalKNELIERLSRYLDDMpAGDPRAVaTRVGPMISEAAATRAQAWIA 349
gi 119715657 268 ADaDLGLAAKVLAKSSTAYaGQVCISAQRILVHedvFEEFSALLADQVSALsVGDPSDEgTDVGPMISLDAARRAEQWVA 347
gi 118470929 267 REsDWEAAADQAVFGAFVQaGQSCVSTQRIFVHedvVDAFTERMAAATRGLvVGDPLDEtVDVSAVINEGEAIRVEKWIA 346
gi 15605756  258 KDgNLEKAVEKTVQGGYAIaGQVCISVQRVFVHedlYDEFIKRLKERVSKLkVGDPMNEdTDLGPMIAPSELERIQEWIS 337
gi 195952919 258 KDaDLEKAATKAVQGGFSMaGQVCISIQRIFVHeyvLEPFLRLLEEKISNIkIGDPMDEeVDMGPMIDKNQVERVKQWIK 337
gi 149176963 270 DDaDLEKAATAVSMAGYANaGQVCISAQRILTSsaiKSDFVDLLKSKVDVLhTGNQLEEtTKIGPMVRETDATRVEQWVN 349
gi 23100694  261 QDaDIETAARLCAKTGYSNsGQSCISVQRIYVQeeiKDNFIELLKQEVSKLkVGDPLDPhTDIGTLVDEKAAGRVIEWIN 340
gi 15614301  263 QDaELMEAVASCVSGAFCAaGQNCIGVQRIYVEqsvFNSFIQSFVAQTKQLrLGDKQSEeTDIGPMISEKEAKRIERWVE 342
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 2494080   377 EAikaGATLLCGNYRe-----GSLYHPTVLEGTpltCRLWHEEVFAPVVMLAPFDtLDKGIEMANDPDYSLHAGIFTNdL 451
gi 91777635  336 EAldgGARLLTGGKCe-----GALFEPTVLHGVdatMKVVCQEVFAPVVSIIEFDdIGEAVAGANASDFGLAAGLFTSdL 410
gi 33597690  350 EAveaGARLVRGGERq-----GAVVQPAVLADVpesCSAWSTEVFSPMVSVRGFArFDDVLASANDTPYGLAAGIFTNdH 424
gi 119715657 348 QAiddGAKLVCGGSRd-----GQFFVPTVVARPaahSALACQEAFAPVAVLIAYRtLREAIDIANSTEYGLQAAVFTEgL 422
gi 118470929 347 EAeagGAKVVVGGGRs-----GAVVTPTIIRGVdpaAKVQCQEVFGPVVTVNSFAeFTEALAAANDSVFGLNAGVFTTnL 421
gi 15605756  338 EAvqkGAKIEAGGLRca--edETIFSPTIVSLVpedSKLFKEEAFAPVVAVNPYKdIEEAIRWVNSSDYGLQVGVFTNdV 415
gi 195952919 338 EAmekGAKVVQKAKNienikgTNYLLPTLLLDVdkdSTIFKEEAFAPVVNINRYKdIDEVVNIINEGDYGLQIGVYTKdI 417
gi 149176963 350 EAvsqGARLVTGGTRq-----GAIYAPTILDNTnpeMQVEKDEIFGPAVALSYFDdIEHAIQMANNTNYGLSAGIFTQdL 424
gi 23100694  341 EAvesGAEIIQGGTKn-----GASVEPTVLFNPpkkSKVVCEEVFGPIVSVIPYKnIEEAIQESNDSPFGLQTGIFTNqI 415
gi 15614301  343 EAkeeGARVLTGGRRt-----GAYFEPTVLTNVspsSRLAKEEAFAPIVIIEGVHsLTEAIARANDVDFGLQAGLFTNnL 417
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
Feature 1                                                                  
gi 2494080   452 NVALEAANrIEVGGVMINDSsdYRFDAMPFGGFKYGSMGREGVRFAYEDMTQPKVVCI 509
gi 91777635  411 KTAFRTAReLAFGGVHINEAssARIDVMPFGGVKDSGFGREGPAYAIREMTEERLITV 468
gi 33597690  425 ARIMSAVRsLRFGTVHINETssARCDVMPFGGVKDSGFGKEGPGYAAREMTEERLIVF 482
gi 119715657 423 DVAMAVARrLDVGGVIVNDAssYRVDSMPYGGVKHSGTGREGVRYAVEEMTESQLVVL 480
gi 118470929 422 RHALQAIEeLEFGSVYINDVptVRADQQPYGGVKESGNTREGPRYAMEEMTELKFITL 479
gi 15605756  416 KLAWKCIKeIEAGGVLINEGptFRADHMPYGGVKYSGIGREGPKFAIEDYTEIKTVIF 473
gi 195952919 418 NMAMEFVRkCEVGGVNINEGpnFRVDHMPYGGFKFSGIGREGPSFAIEDYTEIKNVLI 475
gi 149176963 425 DRAMKFAReVESGNLHINWSsqWRADAMPYGGLKHSGTGKEGPKYAIQEMSEEKMVVI 482
gi 23100694  416 DLAYRVADeMEVGGIVINGTsnFRLDHLPYGGVKNSGIGREGPRYALEEMTESKMVVL 473
gi 15614301  418 TAAFSAIEkLEVGGIMVNDSsdVRIDAMPFGGIKKSGLGREGVRYAIEEMTEQKVVAF 475

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