Conserved Protein Domain Family
ALDH_BenzADH

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cd07152: ALDH_BenzADH 
NAD-dependent benzaldehyde dehydrogenase II-like
NAD-dependent, benzaldehyde dehydrogenase II (XylC, BenzADH, EC=1.2.1.28) is involved in the oxidation of benzyl alcohol to benzoate. In Acinetobacter calcoaceticus, this process is carried out by the chromosomally encoded, benzyl alcohol dehydrogenase (xylB) and benzaldehyde dehydrogenase II (xylC) enzymes; whereas in Pseudomonas putida they are encoded by TOL plasmids.
Statistics
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PSSM-Id: 143470
View PSSM: cd07152
Aligned: 20 rows
Threshold Bit Score: 625.858
Threshold Setting Gi: 118468011
Created: 2-Jan-2009
Updated: 17-Jan-2013
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1175038    35 GDILGITGvangeDVDAAVNAAKRAQKEWAAiPFSERAAIVRKAAEKLKEREYEFADWNVRECGAIrPKGLWEAGIAYEQ 114
gi 111116450  35 GDILGITGvangeDVDAAVNAAKRAQKEWAAiPFSERAAIVRKAAEKLKEREHEFADWNVRECGAIrPKGLWEAGIAYEQ 114
gi 91790351   39 GGTLGQIGiastaDVDRAARSAQSARAAWAAtPFDQRAAVMREAARLLKERAGEINGWNVRECGSImPKAEWELSATYEQ 118
gi 111019975  35 GAVLGEIGaadasDIDRAARRAAAAQPDWAArTGHARADVLRKAAMTLDANRAEVERWLIREGGAVpGKAAFEVDLVLSE 114
gi 78066383   39 GKRLGAIGiassqDVAKAAAIAREAQKAWANvPGPKRGDVLREFSWLVLVHANEIADQIVRETGSIrAKALWEVQVSARE 118
gi 68510508   34 GATLGSVGladegDLERAVDRAVAAQRDWAArPHTERAAVLRRAGDLWQRHADEIERWIMRESGSLrPKAQLETHVAAQE 113
gi 126347956  33 GERLGAVGlvtpeDVGRAAARAAEAQREWAAtPPQRRAAVLRRAGELFTEHAEEIEEWLVREAGSVrSKAGFEARLAIGE 112
gi 152994542  35 GKVLSEVGiatadEVYLACQRANEAQKEWLKvPPRDKATLFHKAAAFMQENFDELALYIARETGGIiPKGQHEVKEAILI 114
gi 28870128   40 SELLMNTAmagaaDIAIACREAALAQPAWAAmGPREKAEIFLMAADHAVCAFDELALYVARETGGSlHKGQHEVNETIVL 119
gi 21229832   52 GGLLHEVGkadlsDVEAAIAQAKHAQRAWAItSPRERAAVFHRAAQLMEAHRAEATLLIARETGGImPKAEREVSEAIAY 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                   #                                    
gi 1175038   115 MHQAAGLASlp--nGTLFPSavpGRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALI 192
gi 111116450 115 MHQAAGLAYls--nGTLFPSavpGRMNLCQRVPVGVVGVIAPWNFPLFLAMRSVAPALALGNAVILKPDLQTAVTGGALI 192
gi 91790351  119 MLMAAALPMqa--nGQMFPStmpGRTNLWRRVPIGTVGVIAPWNFPLLLAMRSVAPALALGNAVLLKPDAQSAVTGGMLI 196
gi 111019975 115 LWEASALPTqp--wGHLLPTsqeGRVSIGRRVPLGVVGVISPWNFPLVLAMRAVAPALALGNAVVLKPDVQTAISGGVVI 192
gi 78066383  119 VLEAAALGSqp--eGVLVATaeaGRQSIARRIPVGVIGVITPWNSPFILGSRAIGPALAMGNAVILKPDVQTPIAGGVTF 196
gi 68510508  114 CFEGAALPSha--lGEILPSe-aPRLSMSKRVPVGVVGVIAPFNFPLILAIRSVAPALALGNAVILKPDPRTAVCGGVAL 190
gi 126347956 113 CFECAGLPThp--qGEVLTSe-eARWSLTRRRPAGVVSVIAPFNFPLILGLRSVAPALALGNAVLLKPDPRTAVSGGVVI 189
gi 152994542 115 LQLAANMTLep--nGLTLPSv-pEKMSYATRKAIGVVGVISPFNFPMILSIRSIAPALATGNAVVTKPDPQTPVTGGFIL 191
gi 28870128  120 LRQAAGMLSqahghGVILPSa-aGRLSYARRVAHGVVGVISPFNFPLVLSLRSVAPALAAGNAVVLKPDPQTPISGGFLI 198
gi 21229832  132 YQQAAGLPLqa--mGQVLPTa-aGQLSLARHLPLGIIAVISPFNFPLILSLRSVAPALAMGNAVILKPDPRTPYTGGVII 208
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                     #                  
gi 1175038   193 AEIFSDaGMPDGVLHVLPGGAdVGESMVANSgINMISFTGSTQVGRLIGEKCGrMLKKVALELGGNNVHIVLPDADLEGA 272
gi 111116450 193 AEIFSDaGMPDGVLHVLPGGAdVGESMVANSgINMISFTGSTQVGRLIGEKCGrMLKKVALELGGNNVHIVLPDADLDGA 272
gi 91790351  197 AQVFADaDLPAGVLHVLPGGPaTGDAVVRHPaVNMISFTGSTAVGRQIGEVCGgLLKKVALELGGNNAIVVLDDADLDAA 276
gi 111019975 193 AQLFAAaGLPEGVLHVLAGDAePGQALSEHPaVSLISFTGSTSVGRQVGATAGrTLKRVSLELGGNNALIVLDDADLDAA 272
gi 78066383  197 ARLFEEaGLPAGLFHVLPGGAdTGSALVNEPlVDMISFTGSTRVGRQIGSIAGgQLKRVSLELGGNNPYIVLEDADIEAA 276
gi 68510508  191 ARIFEQaGLPAGVLSVLPAGAdVGAALVDDPrVPVISFTGSTPAGRAVGAAASrNLKKVHLELGGNSAIVVLDDADLAAT 270
gi 126347956 190 ARIFEEaGLPAGVLHLLPGDGaVGEALVEAPeVRVISFTGSTPVGRIIGEQAGrLLKRAHLELGGNNALVVLPGADVAKA 269
gi 152994542 192 ALALEAaGLPKGVFQVLPGAVeAGEALCAAPeIGMVAFTGSTAAGRKVGEACGrNLKKVSLELGGKSSLIILEDADLDVA 271
gi 28870128  199 ARLFEEaGLPKGLLHVLPGAAdAGEALCRDTnVQMITFTGSTGAGRKVAEAAGrNLKKVSLELGGKNPLVILEDADLDLA 278
gi 21229832  209 AQVLEEaGLPKGLLHVLHGGAdIGQALVEAPdVPMIAFTGSTAAGRRIGELAGrHLKKVALELGGNNAVIVLDDADLERA 288
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                    #  #                                                                
gi 1175038   273 VSCAAWGTFLHQGQVCMAAGRHLVHrdVAQQYAEKLALRAKNLvVGDPNSDqVHLGPLINEKQVVRVHALVESAQrAGAQ 352
gi 111116450 273 VSCAAWGTFLHQGQVCMAAGRHLVHrdVAQQYAEKLALRAKNLvVGDPNSDrVHLGPLINDKQVVRVHALVESAQsAGAK 352
gi 91790351  277 SSCGAWGAFLHQGQICMQAGRHLVHrsVAEAYSQRLKQRAEALhVGNPHAGpAHLGPVINAKQRDRIDQIVQASVaQGAR 356
gi 111019975 273 SSAGAWGSFLHQGQVCMTAGRHIVLesVADRYLEKLTARAANLpVGDPNTGqVALGPLINEHQVANVDRIVRATRdAGAE 352
gi 78066383  277 ASAGAWGAFFHQGQICLTAGRHLVHerVAEAYAAALVRKARALvVGDPFDDrVQIGPIINERQAANVDRIVAETRdQGAT 356
gi 68510508  271 VAAGAAGSFLHQGQVCMTTGRHIVHesVYDEYVAQLAAKAEALpVGDPATEqVALGPIIDHGQLEKIHALVTASVdAGAR 350
gi 126347956 270 ASAGAFGSYLHQGQICMTTGRHIVHesLVEEYTAALAAKADSLpVGDPARQdVALGPIIDRRQLERVHGIVEASVaAGAK 349
gi 152994542 272 ASNIAWGAYFHQGQICMASGRILVQesIAEVLTAKIVEKAKHLpVGDPASGkVALGPLINQRQLEKVHAIVQDTIaAGAK 351
gi 28870128  279 ASNAAFGAWLHQGQICMATGLILVHesIVAAFTRKLADKARALtVGNAARGqAALGPLINQRQLQHVHQVVSDSLqAGAQ 358
gi 21229832  289 ASAIAFGAYLHQGQICMATGRVLVQrgVADALTKLLADKARHLpVGDPVSGtVALGPIIGQRQLQRVLDIVDDSIdAGAV 368
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                                        
gi 1175038   353 VLAGGTYqDRYYQATVIMDVKpeMEVFKSEIFGPVAPITVFDsIEEAIELANCSEYGLAASIHTRaLATGLDIAKRLNTG 432
gi 111116450 353 VLAGGTYqDRYYQATVIMDVKpeMEVFKSEIFGPVAPITVFDsIEEAIELANCSEYGLAASIHTRaLATGLDIAKRLNTG 432
gi 91790351  357 VVTGGTYeGLLYRPTVLTEVQpeMPAFTDEIFGPVAPITVFDtDEEAAALVNASAYGLAAAIHSSnISRAMALANRLHTG 436
gi 111019975 353 IRTGGTFdGLFYRPTVLAGVTpaMPAFQEEIFGPVAPVVVVKdEAEAIAVANDTEYGLVAAIQTGsVERGERLADQLRTG 432
gi 78066383  357 VLAGGTRnGLFFEPTVIVGVRpgMAAFDEEIFGPVAPITTFSsDDEAVALANGTDYGLVAAVASAdLAHAQRIADRLHSG 436
gi 68510508  351 LVAGGTYkGLFYRPTVLADVPagAPAYAREVFGPVAPVVKFStLDEAVALATDTEYGLSLGIFTRdVGKGLALAERIPTG 430
gi 126347956 350 VAAGGEIdGACYRATVLTGVTtrMPAWREEIFGPVAPVISFStPEEAARIVNDCEYGLSVGILGD-VGTAMKLADRIDSG 428
gi 152994542 352 LEAGGTHeGPFYAPTVLSNVKpgMRSFDEEIFGPVVNIVTFKhDDEAVTMANNTQYGLAGAVISNdLSRAQNIGAQLHVG 431
gi 28870128  359 LETGGEYeGLFYRPTVLSGVKpgMRAFEEEIFGPVAVVVSFSsDEQAIELANRSEYGLAAAVISPdVGRATALGDRLRCG 438
gi 21229832  369 VEAGATHdGLFYAATVLSNVRpgMRVFDEEVFGPVINITVFDtDEEAAVLANHGEYGLVAGIMSAsVSRAMVLGEQLHTG 448
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
Feature 1                                                       
gi 1175038   433 MVHINDQpINCEPHVPFGGMGASGsGGRFGG-PASIEEFTQSQWISM 478
gi 111116450 433 MVHINDQpINCEPHVPFGGMGASGsGGRFGG-PASIEEFTQSQWISM 478
gi 91790351  437 MIHINDQtVNNEFHVPFGGMGASGnGGRFGG-PANLEEFTQSQWVSV 482
gi 111019975 433 MVHINDQtLNNDAYAPFGGTGASGnGTRFGT-QSSWDEFTQWQWRTS 478
gi 78066383  437 VIHINDQtVLHEVYGPIGGVGASGnGFNHST-LTNADQFSEWQWITT 482
gi 68510508  431 IAHINDQtVGDEANIPFGGLGASGnGARFGGaANSIEAFTESRWITV 477
gi 126347956 429 KVHINEQtVSDEPHAPFGGVKASGtGSRFGGaTANVEAFTETQWVTV 475
gi 152994542 432 LLHINDQtVNDECINPFGGCGASGnGSAVCG-PADWDLYTHWQWVTV 477
gi 28870128  439 MLHINDQtVADECINSFGGRGASGnGSSAGS-PSDWDEYSQWQWVTV 484
gi 21229832  449 LLHINDQtVADEVINPFGGTGASGnGTSVGG-PADWEQYMHWQWLTI 494

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