2KJZ,3RHE,3SK1


Conserved Protein Domain Family
EhpR_like
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cd07261: EhpR_like 
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phenazine resistance protein, EhpR
Phenazine resistance protein (EhpR) in Enterobacter agglomerans confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. EhpR is evolutionarily related to glyoxalase I and type I extradiol dioxygenases.
Links
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Statistics
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PSSM-Id: 319922
Aligned: 7 rows
Threshold Bit Score: 171.815
Created: 23-Feb-2009
Updated: 18-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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dimer interface
Conserved site includes 44 residues -Click on image for an interactive view with Cn3D
Feature 1:dimer interface [polypeptide binding site]
Evidence:
  • Structure:2KJZ: Agrobacterium tumefaciens putative glyoxylase family protein forms a homodimer, contacts at 4A
    - View structure with Cn3D
  • Structure:3SK1: Pantoea agglomerans Phenazine Resistance Protein Ehpr forms a homodimer, contacts at 4A
    - View structure with Cn3D
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1     #####            #####   #   ##    # ## ##  #          #  #########       ##  ##
2KJZ_A     28 FTILYVdNPPASTQFYKALLGVDPVEssPTFSLFVLANGmKLGLWSRhtvepkasVTGGGGELAFRVENDAQVDETFAGW 107 Agrobacterium tume...
3RHE_A      9 LVLFYVkNPAKSEEFYKNLLDTQPIEssPTFAXFVXKTGlRLGLWAQeeiepkahQTGGGXELSFQVNSNEXVDEIHRQW 88  Legionella pneumop...
3SK1_A     16 LQLVYVsNVERSTDFYRFIFKKEPVFvtPRYVAFPSSGDaLFAIWSGgee--pvaEIPRFSEIGIMLPTGEDVDKLFNEW 93  Pantoea agglomerans
EEA93928    6 SVILYVdDVEKSTEFYTDVLQSGPIErfQEFSLFSLGEDvTLGLQSAegidpkpqPSFGGFELSLSDVSREEVDQVYALW 85  Pseudovibrio sp. J...
YP_854533   6 FTILYVaNPARSTLFYRELFGRPPVEesPTFAMFVFESGaRLALWSSatvepavtQTAGAMELAFALPNDTAVDRQSAEW 85  Aeromonas hydrophi...
NP_798116   6 SFVLYVeNIHVSQTFYSRLFDCEVTLlsPTFASMPLSHSvKLTLKQSdaltpismVKGGGAELSLSVADGHQLELVYNKW 85  Vibrio parahaemoly...
NP_384332   6 LIVLYVmDPPASVEFYRKLLGKEPTAtfPTFSSFEMQDGfVLGLWARekvqpqpiGDGSRAEVAFMVKGEEAVRARYEEW 85  Sinorhizobium meli...

Feature 1               ##  # # #  # #       # ### 
2KJZ_A    108 KASG---VAMLQQPAKMEFGYTFTAADPDSHRLRVYA 141 Agrobacterium tumefaciens str. C58
3RHE_A     89 SDKE---ISIIQPPTQXDFGYTFVGVDPDEHRLRIFC 122 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
3SK1_A     94 TKQKshqIIVIKEPYTDVFGRTFLISDPDGHIIRVCP 130 Pantoea agglomerans
EEA93928   86 KEKG---IPILMEPVDLDFGYTFVATDPDGHRLRVCA 119 Pseudovibrio sp. JE062
YP_854533  86 QARG---LTLIQAPTRMEFGYTCMALDPDGHRLRLYC 119 Aeromonas hydrophila subsp. hydrophila ATCC 7966
NP_798116  86 KEMG---VDFIQPPMTSVYGLNFVATDPDKHRIRVFI 119 Vibrio parahaemolyticus RIMD 2210633
NP_384332  86 RAMG---LPIAQELTRMDFGPTFVALDPDGHRLRVCL 119 Sinorhizobium meliloti 1021

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