Conserved Protein Domain Family
MtMvhB_like

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cd10549: MtMvhB_like 
Uncharacterized polyferredoxin-like protein
This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.
Statistics
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PSSM-Id: 319871
View PSSM: cd10549
Aligned: 77 rows
Threshold Bit Score: 81.6744
Threshold Setting Gi: 41018397
Created: 15-Jan-2016
Updated: 18-Aug-2016
Structure
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Aligned Rows:
 
Fe-S cluster
Feature 1:Fe-S cluster binding site [ion binding site]
Evidence:
  • Comment:predicted based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        #      #### ##   #   #       # #                #  ####  #   ##  ##             
gi 311224916  56 LILDEDKCVLCGMCSSICPYDAldlqIDKKSIKDIpeyptliksseIDEEKCIYCKsCEIVCPqGAITITrelper---- 131
gi 123920     33 PEQNPQQCIGCAACVNACPSNA----LTVETDLATgel-----aweFNLGHCIFCGrCEEVCPtAAIKLSqeyel----- 98
gi 524397125 135 PGKCNFGCLGFGSCVKMCPFHA----ISMSENGLPv----------IDYGKCSGCGiCARQCPqMVLYITsastkihlkc 200
gi 226904332 135 PGQCNFGCFGCGACVDACSFGA----LAMGENGLPq----------FDYDKCVGCGaCASTCPqFLIEMMka-------- 192
gi 524773543 135 RKLCDWGCLGMGSCTDACPTHA----IDVRDGGYAv----------IEQSKCIGCGkCIKACPkHLIERIp--------- 191
gi 526258981 135 SKSCQAGCLGLGSCVKACAFDA----IHVTEGGTAe----------VDPEKCVGCGaCVKACPrAVIDLKp--------- 191
gi 514048056 133 PKECAYACIGLGDCMRVCSFGA----ISMNNGIAS-----------IDPNVCVACGnCEKACPrSAIRLIpaetk----- 192
gi 257796893 133 DKACSWGCLGLGTCVKNCPFDA----MYMQDNGLPg----------VDPVKCTGCGkCVEICPrDIPKLTpesqsta--c 196
gi 41017307  139 GPIFIADCVGCGMCVPECPVDA----ITLDKVGGVi---------eIDEDTCIKCGvCAQTCPwNAVYISgrkpek---- 201
gi 289184533 146 PGACDFGCLGLGDCAAACPFDA----IRVIDNLAV-----------IRSDMCKGCKkCVSVCPqKIIKMFpr-------- 202
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                #                         ####   ### ##                      # #####    
gi 311224916 132 -selvtGEIEIDKDk----------------CIFCGVCEEMCPAAAIEIEwkeptsid-pstandirVDEKKCVYCM--I 191
gi 123920     99 --avwkKEDFLQQSrf--------------aLCNCRVCNRPFAVQKEIDYaiallkhngdsraenhrESFETCPECKrqK 162
gi 524397125 201 nnrdkgKAAMVDCSv---------------sCISCGMCAKVCPVQAITMRedang--------slpvIDHSKCIECG--L 255
gi 226904332 193 -----sNKVLVQCNnrekgkaa--mtdcgvsCISCGLCAKNCPKQAITMEdgvng--------sipvIDYDKCVGCG--L 255
gi 524773543 192 ------KSAVVYIAckncvkgkdvrtfckngCLGCGLCAKLCPQGAITMKdnl------------pvIDYSKCNGCK--T 251
gi 526258981 192 ------LSAVIRVAcnskdtlkavkdvcqvgCMTCRLCEKTCPVKAIIMEnnl------------pvVDKEKCVKCM--A 251
gi 514048056 193 -vlvlcRNKDIGRVaraa---------cmkaCIGCGRCVKECKYGAIAVEdgy------------arIDPEKCTRCG--A 248
gi 257796893 197 lccshdMGKVVKSVcs-------------agCIGCSKCKKECPEEAITMDnfl------------avVDPAKCTGCG--A 249
gi 41017307  202 -rakeiKKFELDEDa----------------CIGCNTCVEACPGDFIVPRtsn-----------ltvELPAICTACG--L 251
gi 289184533 203 ----eeKKATVYCNnqdkgpta--rkacktaCIACGACVRSCPQKAIEIVdnh------------avIDITKCTGCM--T 262
                        170
                 ....*....|....
Feature 1        #   #     #   
gi 311224916 192 CKRVCPv-nAIKVI 204
gi 123920    163 CLVPSD---RIELT 173
gi 524397125 256 CVQKCPrhcLHKLD 269
gi 226904332 256 CVQKCPrkcLVKIT 269
gi 524773543 252 CAAKCPs-kCIKVF 264
gi 526258981 252 CVKKCPt-nALIAY 264
gi 514048056 249 CAKVCPcgcIIDYS 262
gi 257796893 250 CIEVCPt-gVMRSL 262
gi 41017307  252 CEQLCPv-dAIDLE 264
gi 289184533 263 CVNKCPt-sAILPQ 275

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