Conserved Protein Domain Family
RRM_MCM3A_like
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cd12443: RRM_MCM3A_like 
RNA recognition motif (RRM) found in 80 kDa MCM3-associated protein (Map80) and similar proteins
This subfamily corresponds to the RRM of Map80, also termed germinal center-associated nuclear protein (GANP), involved in the nuclear localization pathway of MCM3, a protein necessary for the initiation of DNA replication and also involves in controls that ensure DNA replication is initiated once per cell cycle. Map80 contains one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Links
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Statistics
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PSSM-Id: 409877
Aligned: 13 rows
Threshold Bit Score: 104.709
Created: 1-Jun-2012
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O60318        435 TAIQCKNIPDyLNDRTILENHFGKIAKVQRIFTRrsKKLAVVHFFDHaSAALARKKGKsl---hkDMAIFWHRKK 506  human
XP_002413521  177 TTVLCNGLPAeLNDREALLEHFGQFGRVARITCNprKGCATVRFEDHqSAELAKKRGArisdrcaPLQIFWCSKR 251  black-legged tick
XP_002130399  277 NQLVCTGIPReSNDKDQLRRHFSRFGNVIRVQTNvnKNSASVKFSTNeEAAKAKMKGKnlf--gkAIHIYFGTKS 349  Ciona intestinalis
XP_002592293  424 TTLRCSDVPKmCNDKEFLRRHFSKFGKVVRVNPNrdKNTALISFADHkSASEAKKKGRllqkntrPITIFWGSGK 498  Florida lancelet
XP_001620418  262 KGLVIREIPEaFNKNPWLKRFYSRFGEVAKIICYprKKSASVIFKTHaAAEQAKRKGTvllpgtaPVSIFWKQDK 336  starlet sea anemone
AAT68037      482 TVIQSKNIPSiLNRKDLLMQHFGHFGKVLRVYSSlrKNLAIVHFQDHtSAAKAKKKGKlfq--rnEIQIFWQRKK 554  zebrafish
XP_007907316   27 TAIQCKNIPEhINSKELVKQHFSLFGKVQRVYCYptRSLAIVHFSDHaSAARAKRKGKklr-egvEMEIFWQRKK 100  elephant shark
KQL61144       13 TAIQCKNVPDyLNDRTVLEKHFGQFAKVRRVMTRrnKKMAIIHFFDHaSAALARKKAKel---hkDIVTFWQKKK 84   blue-fronted amazon
XP_005997746  632 TALQCKNIPLrLNQKEIIRKHFQRYGKVQKVYCRphKNLAIVHFCDHaSARKAKRRGKkls--geEIMIFWHKKK 704  coelacanth
XP_013415982  581 VAIVCKNVPKiFNKREALRGHFQKYGPVSKVFVNpnRNQATIHFKNHeGAALAKRKGKylrkdlePLQIFWSSYS 655  Lingula anatina
EKC32540      560 VALICKNVPPrFNNSQKLRQHFSKFGEVARVFPKpeRGMATIHFKTHeSALEAKKKGAvimkgekRMELFWSSYS 634  Pacific oyster
XP_022236380   72 TSIICKGISEeINKKQILQEHFSKFGKVRRITCGpqKNYAVIYFYDHeSAKAAREKGSliksgypPLEIFWSAVQ 146  Atlantic horseshoe...
XP_023217238  274 TSIVCKGIPKeLNNKDFLSNHFSQYGQVKKINCNhkKEYAVVRFCDHeSAANAKKNGAlispqigSVEIFWAQQS 348  bark scorpion
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