Conserved Protein Domain Family
7tmA_GPR150

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cd15198: 7tmA_GPR150 
G protein-coupled receptor 150, member of the class A family of seven-transmembrane G protein-coupled receptors
GPR150 is an orphan receptor closely related to the oxytocin and vasopressin receptors. Its endogenous ligand is not known. These receptors share a significant amino acid sequence similarity, suggesting that they have a common evolutionary origin.
Statistics
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PSSM-Id: 320326
View PSSM: cd15198
Aligned: 4 rows
Threshold Bit Score: 360.277
Threshold Setting Gi: 54037146
Created: 16-Dec-2013
Updated: 26-Jul-2017
Structure
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Aligned Rows:
  next features
Feature 1:putative peptide ligand binding pocket [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                                                       #  ##            
gi 229282330  63 HSRVIALGVLFAAGLCGNLCVCNWMRVHRKkk------sRHNTFVLNLTVADLLVTLITVLSQIIWELMed-aWMAGDVG 135
gi 54037146   43 RVRLVFLGVILVVAVAGNTTVLCRLCGGGGpwag-pkrrKMDFLLVQLALADLYACGGTALSQLAWELLgeprAATGDLA 121
gi 443705389  31 STRLIMLYVTVLIGMIGGVLVFVWLFYNRRrk------sRVNALILHVALGDMLVICWACIFQIIWEHVdr-qWMAGEVA 103
gi 54037145   50 RIHLVFLGIILVAAVAGNTTVLCRLCGGSSgpwpgpkrrKMDFLLVQLAAADLYASGGTALSQLAWELLgdprPALGDLA 129
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        ###### ##  #                                       # #####                      
gi 229282330 136 CRVVKFGQVFAIIASSNMIVLLALDRHNVIIKPfssrWRPWKITAVGWVVSLLLAAPQAYVFrevqd------------- 202
gi 54037146  122 CRFLQLLQASGRGASAHLVVLIALERRRAVRLPhgrpLPARALAALGWLLALLLALPPAFVVrgdspsplpppppptslq 201
gi 443705389 104 CRLLKWLQGIALMASNNLLVVLSIDRHQAIRAPlkqpFRVWKMALLGWSSAFVFSSPQLYIFhvhfvddp---------- 173
gi 54037145  130 CRLSHLLQASGRGASAHLVALIALERQLAVRIPqgpqLPARALAALSWLLALLLALPPTFVVrwdappss---------- 199
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                   #  ### ### ##                                        
gi 229282330 203 ---------edgvPLCRSIFssqpaWHLQIYIIYGATVVFVIPFCILSYTYTRVLAKVWiraragsprelarqadgskkl 273
gi 54037146  202 pgappaarawpgeRRCHGIFaplprWHLQVYAFYEAVAGFVAPVTVLGVACGHLLSVWWrhrpqapaaaapw-------- 273
gi 443705389 174 ------esrfanhTLCEGIFrdmpeYHRQAYLTYVGVLTFYVPLVIIAVCYIRIFLKIAekanqstgqkkvek------k 241
gi 54037145  200 -----tanawpgkHCCRGIFaplprWHLQVYALYEAIVGFAAPVALLGFSCGHLLCVWWqrgsqapvarmpw-------- 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1                                           #  ## ##  #           ## ###  #  ##          
gi 229282330 274 krqvscvaqagnlLPRAKVKTLKMTLVIIMAFVLCGLPYFIVEIKVafgg---msqlDVDVYAVLGVFAVANSAVNPFVF 350
gi 54037146  274 -saspgrapapsaLPRAKVQSLKMSLLLALLFVGCELPYFAARLAAawssgpagdweGEGLSAALRVVAMANSALNPFVY 352
gi 443705389 242 pgklhltsttntsLPKAKIKTLKMTVVIVSSFIICSLPYHILEMIYsfgs---hddvPKKVASILGAMAVANSATNPFVF 318
gi 54037145  267 -spsmaraslpsaLPQAKVQSLKMSLALALLFVGCDLPYFAARLAAawsskpagdweRESLVAAMRVLEVANSAINPLIY 345
                        330
                 ....*....|.
Feature 1                   
gi 229282330 351 LFFNstNKFVH 361
gi 54037146  353 LFFQagDCRLR 363
gi 443705389 319 LVFNvnWACLR 329
gi 54037145  346 LFFQagDCRLW 356

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