5AIM


Conserved Protein Domain Family
Tau138_eWH

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cd16169: Tau138_eWH 
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extended winged-helix domain of tau138 and related proteins
Tau138 is one of three subunits of the tauB subcomplex of yeast transcription factor IIIC. This extended winged-helix domain of tau138 appears to interact with the TPR (tetratricopeptide repeat) array of tauA subunit tau131, and may therefore play a role in linking tauA, tauB, and TFIIIB to regulate the formation of the RNA polymerase III pre-initiation complex.
Links
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Statistics
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PSSM-Id: 320085
View PSSM: cd16169
Aligned: 123 rows
Threshold Bit Score: 60.6753
Threshold Setting Gi: 828222520
Created: 18-Aug-2016
Updated: 18-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5AIM_A          8 SLRSLQRQRAILKVMNtigGVAYlreQFYESVSKYMGSt------tTLDKKTVRGDVDLMVESEk--LGARTEpv----- 74
gi 255729444  743 DSKSELRRNLIIEMTKekgGVAYtssEFLRELDARLGNtt-----tKSDRKTLTRDLARLQESGh--LEVEVVhmqls-- 813
gi 575517673  523 SIKSIKRREALIELIKesgGVVFtsaQLLRSLDRKLDNs------tSTDMKTLVRDIAILVHTGi--VESRDVrtvrs-- 592
gi 459369958  716 DSKGYKRRQVMLDILRedkGVTFtgiDFRRTLDERLGDpn-----nVTDRKTIARDVAKLTESGa--IESEALdvwh--- 785
gi 723186957  707 DVQGESRRDMIVELVEskgGIVIfdaNVTRELDKKLESt------tITDKRTIQRDIEKLQKSGm--IEFELIpstkg-- 776
gi 598064359  545 TIKGTKRRAELLSLIKslgGVAYataSLIKMLDERLSSt------tRTDTKTLARDVSLLVESKd--LETKLFhvmkn-- 614
gi 260951181  567 SVKSMTRRNLLIEIIReegGACFsssVLCRKLDTRMANs------tVTDLKTLARDARHLASEGi--LEIQKAkievg-- 636
gi 831774001  625 TTLYMAREKFVTERIQeqkGVLF---LVLQDQLSKFDD--------KTDQKTLKHLLNEMEKEGk--IKLISLympt--- 688
gi 254565147  574 LTLAYRRRQGILDLLRksdGAALldvSFVHQLDKRISNtt-----aSSDRRTIIRDFEFLTKEGeaiLESFEMecn---- 644
gi 672818052  546 SIALLQRRKVIMTIMEqkrMVEIhatLVAEFHRQKNILfpgdqenvMTDRRTIFRTITVLESEGl--LRVFKIdniplvg 623
                          90       100
                  ....*....|....*....|....*....
5AIM_A         75 ----sGRKIIFL-PTVGEDAIQRYILKEK 98
gi 255729444  814 -gqdvTRSLFYL-TDEGLRPTKEQIDLAR 840
gi 575517673  593 -gqniTRKVLIL-KDENFKPMKEKIEEVQ 619
gi 459369958  786 -agriTKRFLIIsTEENYRPTADRIEEIR 813
gi 723186957  777 -gqpiTRLLIYS-KEERLKPSDDVIEDYR 803
gi 598064359  615 -gqptAKTLLII-TEEGYRPSKEKIEKAK 641
gi 260951181  637 -gqatEKNLMVL-MNPKDRPSEKTLEELK 663
gi 831774001  689 --idnAKNVLFI-MDSKYSVQDQVIKDVI 714
gi 254565147  645 --ngrRKRKLLM-LDLKNKPTPQAIEKAK 670
gi 672818052  624 ggtttKSFCLLPgIQPDSEEVQQFVKDCS 652
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