3EUK,3EUJ,3EUK


Conserved Protein Domain Family
MukF_C

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cd16337: MukF_C 
Click on image for an interactive view with Cn3D
bacterial condensin complex subunit MukF, C-terminal domain
MukF is part of the MukBEF condensin complex that is mainly found in proteobacteria and is involved in chromosome organization and condensation. The complex is believed to serve as a part of the chromosome scaffold rather than a bulk DNA packing protein. MukE and MukF form a stable complex with each other and dynamically associate with MukB, a member of the SMC protein family. MukEF does not bind DNA on its own but modulates MukB-DNA activity. The stoichiometry of the MukEF complex is MukE4F2.
Statistics
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PSSM-Id: 319979
View PSSM: cd16337
Aligned: 22 rows
Threshold Bit Score: 63.4791
Threshold Setting Gi: 501195306
Created: 18-Aug-2016
Updated: 18-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
 
MukF-MukB
Conserved site includes 24 residues -Click on image for an interactive view with Cn3D
Feature 1:MukF-MukB interface [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1        # #  ### #                                             ##  ##  ##  #         ###
3EUK_E        52 LPMALEYESLTdv--qtQIVTAIQAELAHFRNtaqpinlgAVLQEQLARYPq-sRHFDVARIIVDQAVKLgma-sqdHQA 127
3EUK_J        52 LPMALEYESLTdv--qtQIVTAIQAELAHFRNtaqpinlgAVLQEQLARYPq-sRHFDVARIIVDQAVKLgma-sqdHQA 127
gi 145273933  54 LPEELQYESLSdl--hdQIVEHMQGLLIAYREnnrpidlsLVLKEQLENYPl-sHHFDVARIIVDQAVRLgma-nddLSG 129
gi 501195306 343 ARPRADREAAPawvepeRLVADIEALVERALDegaa-tlaEVSSRVLPSLPepvRYAATGRIADAVARRAr-----vRSE 416
gi 522070865 339 VIHDEGDPASIed--fdALKQQVKEWLIDQQKqsgclpsyEHALEQLASQWpmeKLHMVAGWLFSALTEMghq-qsqQHI 415
gi 647295961 356 MPEEVTFEQLTvv--ddTLSQKVSQMLDRHREtgqaidlgRVLKDYLAEHPq-aRHFDLARLVINQAVRMgys-qsdLNA 431
gi 700312861 364 NDDEELVREMPafqlesFAREFVEKVLSDNKPvs----nvSVIRNILSKFPf--NETDRFRLAQCTIKELmkqsdniQDD 437
gi 738890825 362 EDEEQIRETPTfql-eiLAKDIVSKMLNKNKPvs----nvLVVRNVLNNSSl--NKTDRHRLMHCTIKELmrqginyQEQ 434
gi 740349789 347 VPEDVEYEEFQqv--ndVLAAQIGEMLTVHKDqgtpidlgIILKNYLTEHPk-tHHFDLARIVVDQAVRLgys-asdYQA 422
gi 752765518 345 GDPEVILRKTPsdylekLAKGLVARMYESDNEvd----isKVADQILSNEEf--QYKDRHRLLFFIFDELikngdwtRPA 418
                         90       100
                 ....*....|....*....|..
Feature 1         ## #       #####     
3EUK_E       128 VYPVWQPIDd-fSAAVQAHLID 148
3EUK_J       128 VYPVWQPIDd-fSAAVQAHLID 148
gi 145273933 130 IYPDWQAINk-rGAEVQAHVID 150
gi 501195306 417 RERPWAPVLd--RIEIEEWAVD 436
gi 522070865 416 ADSQWHLIIs--EFYAERLSLT 435
gi 647295961 432 IQPDWQAINd-fGAKVQANVID 452
gi 700312861 438 IFPEWVLMDesaNYEIEEQWLI 459
gi 738890825 435 NLPEWVSIDesdLFEIEEQWVI 456
gi 740349789 423 IQPDWQAINe-fGAKVQANVID 443
gi 752765518 419 YHPEWVQLAhdnNVEIEQQWFK 440

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