Conserved Protein Domain Family
DMSOR_beta_like

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cd16372: DMSOR_beta_like 
uncharacterized subfamily of DMSO Reductase beta subunit family
This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.
Statistics
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PSSM-Id: 319894
View PSSM: cd16372
Aligned: 14 rows
Threshold Bit Score: 152.49
Threshold Setting Gi: 344329578
Created: 19-Jan-2016
Updated: 18-Aug-2016
Structure
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Aligned Rows:
 
Fe-S cluster
Feature 1:Fe-S cluster binding site [ion binding site]
Evidence:
  • Comment:predicted based on similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
Feature 1          #      #### ##   #   #         # #             #  ####  #   ##  ##       #    
gi 599129005   2 KKINIKSEYCVNCqQCENVCSNLWFKEINk-EKSCIRILNen---dgIKITVCSQCGECIDICPVQAIYRDAnGVVRINK 77
gi 931546240   2 KVLVFNPERCDGCgICEETCSKTWFKEPDr-HKSAIRISEltdqpghYAANNCNQCGECMDVCPTLALQRDKrGIVRISK 80
gi 941497633   2 KVLVWDEKKCIGCgTCEKVCSQTWFKDENr-EKSRIKILKte---sgFSANICNQCGECINVCPVEALSRNAkGIVILNE 77
gi 973116964   2 KRLVKDERLCIGCgACEEKCSTTYFKVNNr-EKSRIKVEKme---hwSRLTICTQCGVCAEVCPTLALKKDIpGVVRLNK 77
gi 493631438   2 KLLKTYAEKCVRCgACMAACSKAYFKEDDp-SLSRIRVTDvg---smPNINVCNQCGTCIEVCPTQALERDKnGVVQLRK 77
gi 471936355   8 KVLKFYPEKCNGClECERACSMIHFKTKNggEQSAIRIFKkg---ngYQMHVCDHRGLCLDMCPVGALTRKKnGIVWLDK 84
gi 524642095   2 RRLEKDESLCIGChQCEEACSKAFYKVSDp-MKSCIRITDked--gsHHIAVCTQCGKCSEVCNTGVITEDArGVYRLNK 78
gi 780913870   2 KFLDKNEELCTKChLCEEVCAAAINKSDDr-EKSAIRIDDek---diGIINVCNQCGECIEVCSEQAIFKAKnGVILINK 77
gi 260540017   3 KLKVTKGAKCMAClECVRACSTSFYKEFDp-DKSCIQIIEkn---dvAKPMVCVQCGKCAKACPEGAITQNAkGVYMINK 78
gi 167729679   2 KVLKTFPDKCITChNCESACSKLYFKEDNa-EKSCIVINEev---ypPEMIVCNQCGNCIDICPTLALTINTqGVVMLNK 77
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
Feature 1             ####   ### ##         # #####  #   #    #    
gi 599129005  78 KdCVGCFMCVGFCPEGAMFMHpd-yiEPFKCVACGQCVKVCPTGTIEIID 126
gi 931546240  81 RlCVGCLSCVGFCPIVAMRAHae-htVPFKCVACGTCVKECPRDALSIED 129
gi 941497633  78 KtCVGCLSCVGFCPTQSMFQTtg-ivTPFKCISCGACVKTCPTGALSLED 126
gi 973116964  78 KeCVGCFICVGFCPEDAMMQHdd-ylEPFKCISCGLCTEVCPTGAIKIRE 126
gi 493631438  78 DkCTSCMMCVGYCPTASMFFNaakqsQPFKCIACGLCAKACPTGALEIIG 127
gi 471936355  85 NiCIGCQACVGFCPIGAMKKSda-riEPFKCISCGACVRACAENALELVE 133
gi 524642095  79 KeCAGCLMCVGFCPENVMVQCdd-ylEPSKCTACGLCVKACPTGAIRLVE 127
gi 780913870  78 SkCIGCLICVGYCPSLSMIFHed-ipAPFKCIACGKCTDECPSGAIFLKE 126
gi 260540017  79 KkCTGCGKCVEACPFGVMVKAee-apTSSKCIACGICVKACPADVLEIVE 127
gi 167729679  78 SlCIGCLMCVAACPNNAMRFAkg-vyNPFKCIACGSCPKTCPAEAIELVT 126

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