Conserved Protein Domain Family
beta_Kdo_transferase

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cd16436: beta_Kdo_transferase 
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase
KpsC and KpsS are retaining beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferases. They are part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria.
Statistics
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PSSM-Id: 319744
View PSSM: cd16436
Aligned: 4 rows
Threshold Bit Score: 262.866
Threshold Setting Gi: 502593445
Created: 29-Mar-2013
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9977665    91 VVCFGDTrpyhviakrianenqASFWAFEEGYf----------rPYYITLEKDGVNAFSPLPRRADFFLEQfpklaqqey 160
gi 502593445  82 VFLFGDCrpihkaaidsarargVPVWVFEEGYl----------rPDFITLEPGGVNGYSRMPREPELFRHLgralppppe 151
gi 1170705   367 CVVWGVKgeqqwra--eaqrksLPLWRMEDGFlrssglgsdllpPLSLVLDKRGIYYDATRPSDLEVLLNHsqltlaqqm 444
gi 493811194  44 ILGWGLResgqraq-awalragVDVLRIEDGFlrsvslgvlgdaALSIVIDDLGIYYDASRPSRLEMLVKDaatlqddha 122
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9977665   161 kaptpvhggftpmaknairyyielfrnlrkypdyihhrapnaghylkpwslsilkrlnyyiediqiakrveagkygKFFI 240
gi 502593445 152 pasvgstflrhafytaryglalargkrhfphyr--hhrsydprthtlgwlrggvmkpiharreqalmpafegemakRYFL 229
gi 1170705   445 raeklrqrlves--------------------------------------------klskynlgadfslpaeakdkKIIL 480
gi 493811194 123 desrikadhamsli----------------------------------------vrhglskynhapdfvppddwhdDAVL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9977665   241 VPLQVFNDsqvrihcdfpsvrsFLLHVLSSFAEhapadtNIIIKHHPmdrgfidywrdikrfikehpelKGRVIYVHDVP 320
gi 502593445 230 VPLQVHADyqilehspfltvdeMITHVIDSFVAhapddtILVFKHHPldrgnrdygrs-ialrsqalglERRVLAVHDLH 308
gi 1170705   481 VPGQVEDDasiktg---tvsikSNLELLRTVRErnp-haYIIYKPHPdvlvgnrkg-----nipteliaELADYQALDAD 551
gi 493811194 163 IIDQTSGDvavrlg---gadasSFRTMLAAALAenp-gkPVWIKTHPdvmcgkksg----ylvdetfsdPRVRLLPADVS 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 9977665   321 LPVFLRhglgMVTINSTSGLSGLIHNMPVKVLGRAYYDIPGItdqntlaefwnhptppdkelfhayrmyhlnvtqINGNF 400
gi 502593445 309 LPTLLKhargVVTVNSTVGLSAVHHGVPVKVLGNAIYDIAGLtargslaqfwtehpeperelyqgfanylrwtsqHNGNF 388
gi 1170705   552 IIQCIQradeVHTMTSLSGFEALLHGKQVHCYGLPFYAGWGLtvdehhcprreq---------kltiadliyqtlIVYPT 622
gi 493811194 235 SPSLLKrvgkVYAVSSQMGFEALLCGKPVVTFGLPWYAGWGLtddrhvdapvvaar-----rgnatlhqlfgaayLQYCR 309

                 .
gi 9977665   401 Y 401
gi 502593445 389 Y 389
gi 1170705   623 Y 623
gi 493811194 310 Y 310
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