Conserved Protein Domain Family
beta_Kdo_transferase_KpsS_like

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cd16438: beta_Kdo_transferase_KpsS_like 
beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS like
KpsS is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. It is part of the ATP-binding cassette transporter dependent capsular polysaccharides (CPSs) synthesis pathway, one of two CPS synthesis pathways present in Escherichia coli. The poly-Kdo linker is thought to be the common feature of CPSs synthesized via this pathway. CPSs are high-molecular-mass cell-surface polysaccharides that are important virulence factors for many pathogenic bacteria.
Statistics
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PSSM-Id: 319746
View PSSM: cd16438
Aligned: 33 rows
Threshold Bit Score: 254.83
Threshold Setting Gi: 502593445
Created: 22-Mar-2016
Updated: 18-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502593445  82 VFLFGDCRPIHKaaidSARARGVPVWVFEEGYlrPDFITLEPGGVNGYSRMPREPELFRHLgralppppepasvgstflr 161
gi 651523485 113 ICLFNGYHWIDQitkhLADKKGLKTYYFEDGLfrPFTITCDPKGINANSSVPEDPTFYDSLeinedrlsrylykpqfvqy 192
gi 760082296  98 VGVWGGQSVDARavraAAAALDIPCVLFETGLl-PDSTTADARGVNAEASVPADPRFYEAYrcnaelperctpr------ 170
gi 489416213 130 IVWGAGYIPKTIs--yYAKKHQKKLIVMENGYfrPYTLMIDANGVNAENSVPRERAFYEQYpieqdkyikylnrpyfakv 207
gi 808679225  64 VCVWNGTLVPLAaatrVARILGRKTLFFENGCl-PGTTTVDAKGVNYANSLVGKSRSFYDAvqiqteklrqlyetrpair 142
gi 692177960 119 VGVWNGQKLPSSsiaeAAKVLGKEVVYFENGLl-PNSTTCDWSGVNCRNSLPKEGEFYRQFnsakslprtlvsrap---- 193
gi 94428150  107 ICIWNGHRLPEMavkaAARGLDIKIFYFENGLi-PNTTVMDSSGVNAFSSLPKDPNFYLEYakqstdkvdclenkslvar 185
gi 947878568 113 VCLFNGYHWIDQvtkvIAHKRELDVIYFEDGLfrPYTITCDPKGINEMSSIPRSASFYDAIeldekrlkkhlftpesdhl 192
gi 517059263 115 LVMQNDTRWQHSlaiyLANKLDIDYLVFELGLfrPNTITIDSKGVNYNNSVPRKKEFYQNVdidnrfnykeldtdisefk 194
gi 489416635 113 ICTFNGYHWLDQmaqlLARKYRLQMHYFEEGLfrPYTITHDLNGINAEASIPRQPGFYQNIevdqnrlnhylfqpenpsl 192
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502593445 162 hafytaryglalargkrhfphyrhhrsydprthtlgwlrggvmkpiharreqalmpafegemakRYFLVPLQVHADYQIL 241
gi 651523485 193 rkgikesllkvasvkaismmg---sflrihpsfyahitlwqaskyfihkkifqyrspdkvdipkDYLFLPFQVSRDTQIL 269
gi 760082296 171 ----------------------------------------------------klpegtpeplpsRYVFVPFQVALDSQVL 198
gi 489416213 208 ddelsl---------------------------------lykegtviqendittseaklnlemsDYVFVPFQLETDSQII 254
gi 808679225 143 alkt--------------------------------------kwyqkftknkkqgqtedvqlpaKYIFVPFQVHDDTQVL 184
gi 692177960 194 -------------------------------------------------vskkqkgvdaealpeQYIFVPFQVETDSQII 224
gi 94428150  186 ----------------------------------------------kphksrkklrfseadlnkRYVFVPFQVNFDSQVI 219
gi 947878568 193 heknesllvvafvkllsmigs----slhihpnyyvhitfwqglkyffkkrtfsrqiedevelpeEYVFLPFQVSRDTQIL 268
gi 517059263 195 rnlivakymlyyrlgdlfa--------qnsienkkiklldyfkrflktyisktsqkprvkelpeNYIFVPFQVANDSQTL 266
gi 489416635 193 ketlggqilkvafvklvsmfg---slcrlnpklydhinfwqalnyfatkvvfkykkedtfewpaEYVVLPFQMVGDTQIL 269
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502593445 242 EHSPfltvdeMITHVIDSFVAHapd------dtILVFKHHPLDRGnrdygrsialrsqalGLERRVLAVHDLHLPTLLKH 315
gi 651523485 270 YNSDki--stMEELLDHVYSAVqtynrennkqmKIVVKEHPEDISrnnyte----lkkryKNVNNVIFLQKYDIKTLIKN 343
gi 760082296 199 LYSPwi--rgMSQLYWLLEGLMrdvp----eplHLVCKPHPSCSEpyrql------rrhaAGHPRLHIVEQHTSEALIRG 266
gi 489416213 255 SHSAyi--keMKELVLYVLTAVlqynqihkkniKIVFKAHPFFKNdgaalqlgaikkiceTYKEHCYFVSNGNTTDFIRD 332
gi 808679225 185 LNSPkv--ktMAELLAYVVPAIerynretndtiKVVVKEHPSDFGrisyd-----avrekYQDSGIIFLRYYSTPQLIKS 257
gi 692177960 225 SNSPwi--kcMGQLYQHLANVIdktd---tphlHIVIKEHPSEAKrhd---------elhNRHPRIVFANQCETQQLIER 290
gi 94428150  220 VNSPvv--nsMHKLYEFVELLLqetp----sdlLFYIKEHPSDSHtys---------elhKKHDRIQFVDENTEELIRNA 284
gi 947878568 269 YHSPhi--kdMRDLLDHTFNAVkainvaegknlHIVVKEHPEDMSrvnydd----lkeryKNEEEVLFVEKFDIHTLIEK 342
gi 517059263 267 VHSEfn--nmMEFATVVIEAVEkynknnpdnrmSIVFKEHPMDVGkvnydk----fhqkySNNKDIIFVKEAQTKELIKD 340
gi 489416635 270 YNSPhi--ktMERLLKRTVKAVtqinreekrniKIIVKEHPEDISrnnysq----lkrryKDNGNVIFVKKFNVHSLIKN 343
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 502593445 316 ArGVVTVNSTVGLSAVHHGVPVKVLGNAIYDIAGLTARG----SLAQFWtehpe----pereLYQGFANYLRWTSQHNGN 387
gi 651523485 344 AkIIVTINSTVGIEALAMSKPVITLGEAFYNIEGIVYRCkdpeFLGDYItkalki--plnidRMKKFIYYLRFFYQIEGS 421
gi 760082296 267 AeGVLTLNSSVGIEGLLLGRPVLCLGEACYAIPGVAERArs-pEAVRAWlsarangiaveapLRRPFLNWLANEYVIPGS 345
gi 489416213 333 SkMVITINSTVGIEALKQYKNVITLGDAFYNIEGIVKHVtp-tELIKDFerlier--kvhkeLIMKFLYYLRFDYFAEIF 409
gi 808679225 258 SaGVITINSSVGIEALVQHKPVITMGNAFYNVPGLTVNAsdpdDLVAALsvvnq---qpddiLIDKFLYYLRYHYLAAGS 334
gi 692177960 291 SqAVLTINSTVGIESLLLGKSVMTMGEACYGIRGVCESIeseaVLLKKLnqldac--hgepeIKNGFLHFLHEHYVIPTA 368
gi 94428150  285 D-AVLTLNSSVGIEASMLGKPVIVLGNACYAIQKLVYVStsfrQVAEILnnleq----pdqkVRQAFFSYLENKYLLPGA 359
gi 947878568 343 AeAVVTINSTVGIEALAKTKRVVTLGDAFYNIEGVVHHArtpgELPETLnkslht--kvnrgRIRKFIYYLRFHYQIEGS 420
gi 517059263 341 SkLIITINSTVGIEALEMGKKVICLGRCFYAIEEIALQSnr-iDLANDIsymlnk--klnrsLINNFLDYIKYEYQFEGN 417
gi 489416635 344 AlAVITINSTVGIEALAQHKRVITLGEALYNIEGITWNCkhpsDLANVLktslne--qvnhaLIDKYLYYLRFHYQIEGT 421

                 ..
gi 502593445 388 FY 389
gi 651523485 422 IN 423
gi 760082296 346 FR 347
gi 489416213 410 YP 411
gi 808679225 335 WR 336
gi 692177960 369 WN 370
gi 94428150  360 WQ 361
gi 947878568 421 LQ 422
gi 517059263 418 EY 419
gi 489416635 422 LN 423
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