Conserved Protein Domain Family
RING-HC_prokRING

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cd16528: RING-HC_prokRING 
RING finger, HC subclass, found in prokaryotic RING finger family proteins
The family corresponds to a group of uncharacterized prokaryotic C3HC4-type RING-HC finger containing proteins. The RING finger is fused to an N-terminal alpha-helical domain, ROT/Trove-like repeats, and a C-terminal TerD domain, suggesting a possible role in an RNA-processing complex.
Statistics
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PSSM-Id: 319442
View PSSM: cd16528
Aligned: 5 rows
Threshold Bit Score: 62.1138
Threshold Setting Gi: 115534279
Created: 31-Mar-2013
Updated: 18-Aug-2016
Structure
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Aligned Rows:
 
Zn binding siteRING-HC finger
Feature 1:Zn binding site [ion binding site]
Evidence:
  • Comment:Based on the structural evidence that Homo sapiens MSL2 (4B7Y) binds two Zn2+ ions through its RING-HC finger.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
Feature 1          #  #               # #  #  #        #  # 
gi 123374064 105 QPCIHCGa----qGTVRALSPCAHLVCERCYDGSDYsACPICH 143
gi 737391420 115 QPCLHCSk----vGTTHVLNPCRHVVCDACFDGSNHsACPICE 153
gi 639191831 114 QPCLFCGh----hDTVHVLNPCQHIVCDHCFDGSNYsACPVCE 152
gi 270508558 135 QPCVLCGk----aGAVHAVSPCAHLVCHACWDGSDFaGCPICH 173
gi 115534279   7 VLCIKCSlvfdekTRRPCTGTCNHSICEQCFDQKHSpSCPICN 49

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