Conserved Protein Domain Family
dRING_RMD5B

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cd16795: dRING_RMD5B 
Degenerated RING finger found in protein RMD5 homolog B (RMD5B)
RMD5B is one of the vertebrate homologs of yeast Rmd5p. The biological function of RMD5B remains unclear. RMD5B contains a Lissencephaly type-1-like homology motif (LisH), a C-terminal to LisH motif (CTLH) domain, and a degenerated RING finger that is characterized by lacking the second, fifth, and sixth Zn2+ ion-coordinating residues compared with the classic C3H2C3-/C3HC4-type RING fingers.
Statistics
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PSSM-Id: 319709
View PSSM: cd16795
Aligned: 5 rows
Threshold Bit Score: 107.796
Threshold Setting Gi: 465966123
Created: 14-Apr-2015
Updated: 18-Aug-2016
Structure
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Aligned Rows:
Conserved Features/SitesClick to see Conserved Features Help
 
degenerated
Feature 1: degenerated RING finger [structural motif], 8 residue positions
Conserved feature residue pattern:C L C H S A C CClick to see conserved feature residue pattern help
Evidence:
  • Comment:The degenerated RING finger is characterized by lacking the second, fifth, and sixth Zn2+ ion-coordinating residues compared with the classic C3H2C3-/C3HC4-type RING fingers.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
Feature 1          #  #              # #  #  #           #  #   
gi 29840869  336 FACPILRQQTSDSNPPIKLICGHVISRDALNKLingGKLKCPYCPME 382
gi 632948303 335 FACPILRQQATDSNPPMKLICGHVISRDALNKLingGKLKCPYCPME 381
gi 465966123 388 FACPILRQQTTDSNPPIKLICGHVISRDALNKLingGKLKCPYCPME 434
gi 37595352  333 FACPILRQQTSESNPPMKLICGHVISRDALNKLtnaGKLKCPYCPME 379
gi 556965924 335 FACPILRQQTTDSNPPMKLICGHVISRDALNKLniaGKLKCPYCPME 381

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