Conserved Protein Domain Family
Myosin_IXb_RA
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cd01779: Myosin_IXb_RA (this model, PSSM-Id:176374 is obsolete and has been replaced by 340477)
ubitquitin-like domain of Myosin_IXb_RA
Myosin_IXb_RA RasGTP binding domain from guanine nucleotide exchange factors. In some proteins the domain acts as a RasGTP effector (AF6, canoe and RalGDS, for example), but in other cases it may not bind to RasGTP at all.
Links
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Statistics
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PSSM-Id: 176374
Aligned: 4 rows
Threshold Bit Score: 203.56
Created: 2-Aug-2004
Updated: 17-Jan-2013
Structure
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Aligned Rows:
Download Cn3D
 
putative Ras
Feature 1:putative Ras interaction site [polypeptide binding site]
Evidence:
  • Comment:interacts with the switch I and switch II regions of Ras
  • Citation:PMID 9628477
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                 # #            ## ##   ##       #  ##                                
NP_004136    7 GSSGRREQAAYHLHIYPQlstteSQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLVEVKESGGEEWVLDANDSPVH 86   human
Q63358       7 GSSGRRRPATFHLHIYPQlpsagSQTSCRVTATKDSTTSDVIRDVVASLHLDGSKHYVLVEVKESGGEEWVLDASDSPVH 86   Norway rat
CAG08020    24 GSPNNHDSRSYLLQIYPRlv-aqPTSCCNLRVHKDATAASVISDVAAVLGLDPARMYVLAEVKESGGEEWVLEPGDLPAQ 102  Tetraodon nigrov...
XP_413711    7 GGRRRFEDSEYTLHIYPGsi-aeGTIYCPITARKTSTAAEVIDSLINKLQLEKTKCYVLAEVKEFGGEEWILNPTDCPVQ 85   chicken

Feature 1                                
NP_004136   87 RVLLWPRRAQDEHPQEDGYYFLLQER 112  human
Q63358      87 RVLLWPRRAQKEHPREDGYYFLLQER 112  Norway rat
CAG08020   103 RFLLWPRKAQEQHPQSLGFYFLLQER 128  Tetraodon nigroviridis
XP_413711   86 RMMLWPRMALENRTSGEDYRFLLREK 111  chicken

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