2ATX,2NTY,1I4D,1LB1,1DOA,3A58,2J1L,1GWN,3Q3J


Conserved Protein Domain Family
RHO
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smart00174: RHO 
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Rho (Ras homology) subfamily of Ras-like small GTPases
Members of this subfamily of Ras-like small GTPases include Cdc42 and Rac, as well as Rho isoforms.
Links
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Statistics
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PSSM-Id: 197554
Aligned: 43 rows
Threshold Bit Score: 240.208
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2ATX_A        21 CVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTV-GGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSV 99  human
XP_002923272  26 IVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEI-DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDI 104 giant panda
EAW60919      10 IVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEI-DKRRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDI 88  human
NP_055285     16 LVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET-EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDI 94  human
NP_031511     20 VVLVGDGGCGKTSLMMVFAKGAFPESYSPTVFERYNATLQM-KGKPVHLQIWDTAGQDDYDRLRPLFYPDANVLLLCFDV 98  house mouse
P33153        78 IVVVGDGGCGKTCLLLAYTQNKFPSIYVPTVFENYVTAVQSpNGKTVELALWDTAGQEEYDRLRPLSYPDVDILLVCFAV 157 Candida albicans
BAA00897      19 IVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFV-DSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSI 97  baker's yeast
AAA34978      10 LVIIGDGACGKTSLLYVFTLGKFPEQYHPTVFENYVTDSRV-DGIKVSLTLWDTAGQEEYERLRPFSYSKADIILIGFAV 88  baker's yeast
2J1L_A        37 VVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQV-KGKPVHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDV 115 human
1GWN_A        31 IVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEI-DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDI 109 house mouse

2ATX_A       100 VNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRd---dPKTLARLNDMKEKPICVEQGQ------------------ 158 human
XP_002923272 105 SRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRt---dVSTLVELSNHRQTPVSYDQGA------------------ 163 giant panda
EAW60919      89 SRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRt---dLATLRELSKQRLIPVTHEQGTv----------------- 148 human
NP_055285     95 SRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRt---dLSTLMELSHQKQAPISYEQGCa----------------- 154 human
NP_031511     99 TNPNSFDNVSNRWYPEVTHFCKGVPIIVVGCKIDLRk---dKVLVNNLRKKRLEPVTYHRGHd----------------- 158 house mouse
P33153       158 DNEVSLENVKDMWFPEVNHYCPGIPIILVGTKSDLL-----SDMNHDASIR----------------------------- 203 Candida albicans
BAA00897      98 DSRDSLENVQNKWVGEITDHCEGVKLVLVALECDLRnneneSNAITPNNIQQDNSVSNDNGNninstsngknlisyeegl 177 baker's yeast
AAA34978      89 DNFESLINARTKWADEALRYCPDAPIVLVGLKKDLRq---eAHFKENAT-DEMVPIEDAKQ------------------- 145 baker's yeast
2J1L_A       116 TSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRk---dKSLVNKLRRNGLEPVTYHRGQ------------------ 174 human
1GWN_A       110 SRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRt---dVSTLVELSNHRQTPVSYDQGA------------------ 168 house mouse

2ATX_A       159 KLAKEIGACCYVECSALTQKG-LKTVFDEAIIAILTP 194 human
XP_002923272 164 NMAKQIGAATYIECSALQSENsVRDIFHVATLACVNK 200 giant panda
EAW60919     149 -LAKQVGAVSYVECSSRSSERsVRDVFHVATVASLGR 184 human
NP_055285    155 -IAKQLGAEIYLEGSAFTSEKsIHSIFRTASMLCLNK 190 human
NP_031511    159 -MARSVGAVAYLECSARLHDN-VEAVFQEAAEVALSS 193 house mouse
P33153       204 -VAKEIGAIGLIFTSAKTMFN-VRTVFNFALNHfqrn 238 Candida albicans
BAA00897     178 AMAKKIGALRYLECSAKLNKG-VNEAFTEAARVALTA 213 baker's yeast
AAA34978     146 -VARAIGAKKYMECSALTGEG-VDDVFEVATRTSLLM 180 baker's yeast
2J1L_A       175 EMARSVGAVAYLECSARLHDN-VHAVFQEAAEVALSs 210 human
1GWN_A       169 NMAKQIGAATYIECSALQSENsVRDIFHVATLACVNK 205 house mouse
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