Conserved Protein Domain Family
TBX

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pfam12598: TBX (this model, PSSM-Id:204975 is obsolete and has been replaced by 403708)
T-box transcription factor
This domain family is found in eukaryotes, and is typically between 77 and 89 amino acids in length. The family is found in association with pfam00907. There are two completely conserved residues (S and P) that may be functionally important. T-box genes encode transcription factors involved in morphogenesis and organogenesis of vertebrates and invertebrates
Statistics
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PSSM-Id: 204975
View PSSM: pfam12598
Aligned: 15 rows
Threshold Bit Score: 62.1179
Threshold Setting Gi: 342187140
Created: 28-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q1PHR0 315 NEASKHTDqaEVstSSIKQYSEPRVGHVREPPVvlSPLKSVSAEANSTTRIEEEIDVDVesNDRDDEEETAANElklria 394 Saccoglossus kowalevskii
Q4VA43 303 RVFEERHK--KE--TSDESSSEQAAFNCFAQAS--SPAVSIVGTSNLKDLCPSEAESDAeaESKEEHGPEACDA------ 370 house mouse
Q9PUM1 308 RSYDEHQK--KDngSSDESSSEQTAYKCFAQTS--SPTAPAVGTSTLKGVPPSDGDSDE--ESRDEGGPDTGES------ 375 African clawed frog
O73718 305 RVYDERQK--KEnpTSDESSNEQTAFKCFAQSS--CPAVPAVGTSSFKDLCPGEVDRDX--DSXDDXXLEXSEW------ 372 chicken
Q9PVX2 173 RVYEDHQK--KDtaTSDDSSSEQPSYKCFAQPS--SPAISTVGTSTQKALCHSEEESDA--DSKDDPILETQES------ 240 Japanese firebelly newt
O73717 295 RMYEEPCKpdRDggESDAXSCEPSAVR--DXLX--SPVGPLPSPLRLKG------------SGREEK-PGADSD------ 351 chicken
Q6PCL0 295 RMYEEQCKadRDgaESDASSCDPAPGR--DSLH--SPLSAAPSPLRLHR------------TNREEK-FGADSD------ 351 African clawed frog
Q9PVX4 182 RMYEDHCRpdRDgaESDASSCEPALGR--DILN--SPLSAEPSPLRLSR------------SIRDEK-SCVDSD------ 238 Japanese firebelly newt
Q7ZTU9 294 RMYEDQCKvdRDgaDSDASSSEPTTGR--DAGH--SP-GPVSSPLRFNR------------GSRDDK-TCTDSE------ 349 zebrafish
Q60707 305 RLYEEHCKpeRDgaESDASSCDPPPAR--EPPP--SP-SAAPSPLRLHR------------ARAEEKPGAADSD------ 361 house mouse
Q1PHR0 395 alEEAKDAMGEKDGDENSSADEE 417 Saccoglossus kowalevskii
Q4VA43 371 --AKISTTTAEEPGRDKGSPATR 391 house mouse
Q9PUM1 376 --TKISTTTSEDCRELASPPRAP 396 African clawed frog
O73718 373 --GKISTTTXTHPWXQPAXGRQR 393 chicken
Q9PVX2 241 --SKISTTTREEPRERTNPAKGH 261 Japanese firebelly newt
O73717 352 --AEVEKVSEERPVGG-SPGRED 371 chicken
Q6PCL0 352 --QE-LDRREVRSARGHSPVGHR 371 African clawed frog
Q9PVX4 239 --QEDLDKPEDRSVGSHSPEGEA 259 Japanese firebelly newt
Q7ZTU9 350 --HE-MDHQNDRCGGSSSPAPEP 369 zebrafish
Q60707 362 --PEPERTGEERSAAPLGRSPSR 382 house mouse
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