1G96,1YVB,1RN7,1EQK


Conserved Protein Domain Family
CY

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smart00043: CY 
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Cystatin-like domain
Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.
Statistics
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PSSM-Id: 214484
Aligned: 57 rows
Threshold Bit Score: 56.6677
Threshold Setting Gi: 4504489
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1G96_A      8 RLVGGPMDasVEE-EGVRRALDFAVGEYNKA--S-ND--MYHsrALQVVRARK-QIVAGVNYFLDVELG----------- 69  human
O08677    140 pCIGCVHAisTDS-PDLEPVLKHSIEHFNNN--T-DH--SHLftLRKVKSAHR-QVVAGLNFDITYTIV----------- 201 house mouse
AAA42251  262 NCRGCPREipVDS-PELKEALGHSIAQLNAQ--H-NH--IFYfkIDTVKKATS-QVVAGVIYVIEFIAR----------- 323 Norway rat
AAA41489  140 LCVGCFQPipMDS-SDLKPVLKHAVEHSNNN--T-KHthLFAlrEVKSAH--S-QVVAGMNYKIIYSIV----------- 201 Norway rat
NP_786968 262 LCAGCPKPipVDS-PDLEEPLSHSIAKLNAE--H-DG--AFYfkIDTVKKATV-QVVAGLKYSIVFIAR----------- 323 cattle
NP_786968 140 eCLGCVHPisTKS-PDLEPVLRYAIQYFNNN--T-SH--SHLfdLKEVKRAQR-QVVSGWNYEVNYSIA----------- 201 cattle
CAA05210   22 gtglGFRElaCDD-PEAEQVALLAVDYLNNHllQ-GF--KQVlnQIDKVKVWSrQRPFGVVYEMEVDTL----------- 86  house mouse
P29695     18 lssqvrgDleCDD-KEAKNWADDAVRYINEHklH-GH--KQAlnVIKNICVVP-WNGDLVAVFLELNLL----------- 81  habu
P31727     21 QCVGCPSEvkGDKlKQSEETLNKSLSKLAAG--D-GP--TYKl--VKINSATT-QVVSGSKDVINADLK----------- 81  Sarcophaga peregrina
NP_036850  31 RGMEIFEKnfIDK-NKLKDVYDVFKYLYNTH--SaDT--YLSn-IKNESFTMN-IWGFGEIEMVKTKCRkidsdfykcsf 103 Norway rat
1G96_A     70 ----------------------RTTCTKtq--pNL-DNCpfhdqphlkrkafcsfqIYAVPWQGTMTLSKSTCQ 118 human
O08677    202 ----------------------QTNCSKerfpsLH-GDCvalpngd---dgecrgnLF-MDINNKIANFSQSCT 248 house mouse
AAA42251  324 ----------------------ETNCSKqskteLT-ADCetkhlgq---slncnanVYMRPWENK-VVPTVRCQ 370 Norway rat
AAA41489  202 ----------------------QTNCSKedfpsLR-EDCvplpygd----hgectghTHVDIHNTIAGFSQSCD 248 Norway rat
NP_786968 324 ----------------------ETTCSKgsneeLT-KSCeinihgq---ilhcdanVYVVPWEEK-VYPTVNCQ 370 cattle
NP_786968 202 ----------------------QTNCSKeefsfLT-PDCkslssgd---tgectdkA-HVDVKLRISSFSQKCD 248 cattle
CAA05210   87 ----------------------ETTCHAld-ptPL-ANCsvrqltehavegdcdfhILKQDGQ--FRVMHTQCH 134 house mouse
P29695     82 ----------------------ETECHVld--pTPvEKCtvrqqhnhavemdcdakIMFNV-ETFKRDVFVKCH 130 habu
P31727     82 ----------------------DENDKtktc----------------------ditIWSQPWLENGIEVTFNCp 111 Sarcophaga peregrina
NP_036850 104 qrefynlkrtpgetmyyislpgSVRCRKll--sKL-DNCpfeeqteqlkreicyfvVYPDYIEQNIHAVRFDCY 174 Norway rat
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