1N7D,1NPE,1NPE


Conserved Protein Domain Family
LY

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smart00135: LY 
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Low-density lipoprotein-receptor YWTD domain
Type "B" repeats in low-density lipoprotein (LDL) receptor that plays a central role in mammalian cholesterol metabolism. Also present in a variety of molecules similar to gp300/megalin.
Statistics
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PSSM-Id: 214531
View PSSM: smart00135
Aligned: 189 rows
Threshold Bit Score: 29.8773
Threshold Setting Gi: 6978797
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1N7D_A        398 YTSLIPnLRNVVA-LDTEVASNRIYWSDLSqrMICSTQLDRAHG 440  human
Q92673        780 EQLPLTgLRAAVA-LDFDYEHNCLYWSDLAldVIQRLCLNGSTG 822  human
Q04901        880 QRLYGR-YDQTPIgLTYDCTNKMYYWSSVVkrAIYSAELEGDGS 922  Halocynthia roretzi
Q14112       1134 KTLLSL-HGSIIVgIDYDCRERMVYWTDVAgrTISRAGLELGAE 1176 human
Q93791       1309 KQLIVI-PHHIPVgIDFDCKEEKIVWSDMSghSIRTSSLNGTEH 1351 Caenorhabditis elegans
XP_001155886  839 FLHVPA-KVIIG--LAFDCVDKMVYWTDITepSIGRASLHGGEP 879  chimpanzee
NP_004516    3219 YSLILEgLDNVVA-LDFDRVEKRLYWIDTQrqVIERMFLNKTNK 3261 human
NP_034243      74 QQLVVDaGISAD--MDIHYKKERLYWVDVErqVLLRVFLNGTGL 115  house mouse
XP_003310495   67 EQLVVDaGVSVI--MDFHYNEKRIYWVDLErqLLQRVFLNGSRQ 108  chimpanzee
EDL82180      151 SRVLLS-SLKRPAnILVDPTERLIFWSSVVtgNLHRADLGGMDV 193  Norway rat
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