1BP1


Conserved Protein Domain Family
BPI1

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smart00328: BPI1 
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BPI/LBP/CETP N-terminal domain
Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) N-terminal domain
Statistics
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PSSM-Id: 214622
Aligned: 18 rows
Threshold Bit Score: 125.968
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1BP1_A         8 RISQKGLDYASQQGTAA---LQKELKRIKIPDYSDSFKIKHl--------------GKGHYSFYSMDIREFQLPS---SQ 67  human
Q18869        50 RILPRGLAYLNHLAANL---LADQLPRLILPDVEHILPSNQ---------------GIIYISKVHLSRFRRAEHH---QL 108 Caenorhabditis ...
O17781        66 RLNSRAFQYASTLVGGI---LNTEIKKARIPPISQCIPMVQ-----------------GCVNIYNLYVSRYRCPQr-vVL 124 Caenorhabditis ...
O17768        42 riMPNGLAYLREVGMKV---INEQILKLQLPNIREPIEN-------------------GEVSIYNLQMSKYWAPQe-yAL 98  Caenorhabditis ...
Q17151         1 ---QEALDYGSRIAPDV---LRKVLNKASFENLEDKE-------------------GPVSYKFSKISLEQSEIES---AN 52  Biomphalaria gl...
Q17738        19 RVTPTGTQYVASVVAAA---FSSHFADIKPPKERKDHQLTT----------------ISTVTLRRLMLETLQLDKq-lVT 78  Caenorhabditis ...
Q05701        30 RIDKDELGKAIQNSLVGgpiLQNVLGTVTSVNQGLLGAGGLlgggg------llsyGGLFSLVEELSGLKIEELT---LP 100 Norway rat
Q05704       171 GGLLGTGGILANEGILA---GQGGLLGGGGLLGDGG----LlggggvlgvlgeggiLSTVQGITGLRIVELTLPR---VS 240 Norway rat
XP_002826500  31 RITKPALLVLNQETAKV---IQTAFQRASYPDITGEKAMMLl--------------GQVKYGLHNIQISHLSIAS---SQ 90  Sumatran orangutan
NP_509863     21 RVNEFGLHEAANFTRQW---LSMAGPHMKMPEIR------Qs--------------FYNSFAGGEMTVTNITIKRfvpPL 77  nematode
1BP1_A        68 ISMVPNVg-LKFSISNANIKISGKWKAQKRF-------LKMSGNFDLSIEGMSISADLKLGSNPtsg--kpTITCSSCSS 137 human
Q18869       109 NSTAPNK--ISWTMQNMDIGLLGDLSGSVNIvv----pLNLTGQVEILAQGLTFHLESSIEKGKng---saKVTSLSCLA 179 Caenorhabditis ...
O17781       125 YPAPPNR--IVLQVQNVDLGVTGNLGGQIVVll----pIALSGIVQLNIHQATITVQLAIERGPrg----pYVRLLSCDM 194 Caenorhabditis ...
O17768        99 DMSEPST--FAWSMSKMHLRAAGDFQATLNSpll-lptVPITGHFEALLGHISLYITVNMERNAng---apQVRSTGCRS 172 Caenorhabditis ...
Q17151        53 FSFDPSIngIRASIQRLSAFVRLDYESSIDM-------SITKMEHSGSVDIPSGCRCGPESCRErds-vrrAKPNLECKA 124 Biomphalaria gl...
Q17738        79 TTTSDGL--LRITVQNISVSSSAVLSGELRE-------IKLQDNVTFRTANLRIDTAIRIMKNAgg---npALKMESCKI 146 Caenorhabditis ...
Q05701       101 TVSIKL---LPGVGVQLSLHTKVSLHGSGP----------LVGLLQLAAEVNVSSKVALGMSPRgt----pILILKRCNT 163 Norway rat
Q05704       241 VRLLPG---VGVYLS-LYTRVAINGKSLIGF-------------LDIAVEVN-ITAKVRLTMDRtg---ypRLVIERCDT 299 Norway rat
XP_002826500  91 VELVEAKs-IDVSIQNVSVVFKGTLKYGYTT-------AWWLGIDQSIDFEIDSAIDLQINTQLtcdsgrvRTDAPDCYL 162 Sumatran orangutan
NP_509863     78 IRFRPSDh-SFLYMSTLSGYAQVSAEWAVESqflhmlkIPLEGQIHAQMTGLISEIAMQITQDN-------EVEVHHCVA 149 nematode
1BP1_A       138 HINSVHVHIS--Ks-KVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSKLQPY---FQTLPVMTKId--------sVA 203 human
Q18869       180 TIRDVTVTNHngG--LFGLAVSVFKQGVSDNVRHMLQTIICKKVRKYIDEDANEK---LAEAQTSSKLad-------aLE 247 Caenorhabditis ...
O17781       195 QIGYADAYIEngGl-VGDIVNSQFRSQISNQVRQMIPGQVCGQLPTIINEKINSK---LGALPQTVALqq-------mIS 263 Caenorhabditis ...
O17768       173 AIGYVDLNVRntGv-ITDFFINAFKAFLIGNFKPQVEQKMCKMIESIIDRDMNIL---LSNMPLKIRInen-----nlDI 243 Caenorhabditis ...
Q17151       125 SIKDSEFNFS--Si-VVHWMYSTMSKVLPNKVREWTEERLCRVITDYIDNKMPET---IKEVKLSAEMd---------EF 189 Biomphalaria gl...
Q17738       147 VTQGIKLVT---Kp-MDPRNGKSLADAIANDANTMFSDLICSKIDHIVSNRVNQR---FALLSSRISLe--------dSK 211 Caenorhabditis ...
Q05701       164 LLGHISLTS--------GLLPTPIFGLVEQTLCKVLPGLLCPVVDSVLSVVNELLgatLSLVPLGPLGsveftlatlpLI 235 Norway rat
Q05704       300 LLGGIKVKL------LRGLLPNLVDNLVNRVLANVLPDLLCPIVD-VVLGLVNDQ---LGLVDSLVPLg--------iLG 361 Norway rat
XP_002826500 163 SFHKLLLHLQ--GerEPGWIKQLFTNFISFTLKLVLKGQICKEI-NVISNIMADF---VQTRAASILSd--------gDI 228 Sumatran orangutan
NP_509863    150 QIRDLRVAFE--Gs-VAADVIHWFRQSITRAIRRTLEEEYCDMMRNHWLPWVEAQ---LYQFPTNLTIs----------H 213 nematode
1BP1_A       204 GINYGLVAPPAT---T-------AETLDVQMKGEFYSENH 233 human
Q18869       248 TNALKMISVGGD---Eksr-idiSSIFDSSLASKFFIDFR 283 Caenorhabditis elegans
O17781       264 LFGGALGLGGGG---G-------GTCPSTCPKQPVFIPST 293 Caenorhabditis elegans
O17768       244 IGETFGVAPRKH---H-------RAGKLSNLNAKNITLTH 273 Caenorhabditis elegans
Q17151       190 KVDYSPVSKVSV---S-------QQSLKPDTGVKFQWKSD 219 Biomphalaria glabrata
Q17738       212 NFDIVKIIMQAE------------ERLKRLVRQNMLRSNK 239 Caenorhabditis elegans
Q05701       236 SNQYIELDINPI---VksiagdvIDFPKPRLPVKMPPKED 272 Norway rat
Q05704       362 SVQYTFSSLPLV---T-------GEFLELDLNTLVGEAGG 391 Norway rat
XP_002826500 229 GVDISLTGDPVI---T-------ASYLESHHKGHFIYKNv 258 Sumatran orangutan
NP_509863    214 NPDVTLIQTMQSiamT-------QHHVDVRMRSDLIWDDE 246 nematode
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