1GGU,1L9M,1X3Z


Conserved Protein Domain Family
TGc

?
smart00460: TGc 
Transglutaminase/protease-like homologues
Transglutaminases are enzymes that establish covalent links between proteins. A subset of transglutaminase homologues appear to catalyse the reverse reaction, the hydrolysis of peptide bonds. Proteins with this domain are both extracellular and intracellular, and it is likely that the eukaryotic intracellular proteins are involved in signalling events.
Statistics
?
PSSM-Id: 214673
View PSSM: smart00460
Aligned: 47 rows
Threshold Bit Score: 36.2067
Threshold Setting Gi: 11497698
Created: 13-Jul-2011
Updated: 16-Jan-2013
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1GGU_B       293 ENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQmdifleedgnvnskltkdSVWNYHCWNEAWM--Trp 370
gi 4049518   155 LLDSRKGRCGEWANCFTFLCRALGSRARWIWN--------------------------------AEDHVWTEVYS--Nk- 199
gi 2650741   108 IAYFKVGGCGELARLFCEAAKRAGFEARVVSDL-------------------------------GYDHAWVEVKI--N-- 152
gi 74676322  183 LLETRKGRCGEWCNLFTLILKSFGLDVRYVWN--------------------------------REDHVWCEYFS--Nf- 227
gi 81345627  157 CLDGGFGICGNHQYLFLELMHRLGLEARSVGFWYIDPNAN-----------------------SRASHAAAEVLV--D-- 209
gi 259145127 516 ILYRKHCTPYELTWLFKKLANSLGITCEIVIGFLKTPSAINW--------------------EFKYNHCWLRILV--N-- 571
gi 19114473  528 VISEGQGTPFEVALLVKEMLQALDLWCEVIEGYLKSPDDIYYTR------------------DININHAWNVVTF--D-- 585
gi 16329385  190 VLARGETICSGYSNLYQALAKELGLDVVIIEGFAKGGDVIVGD-------------------DPDVNHAWNGVKI--D-- 246
1X3Z_A       176 LLETRKGRCGEWCNLFTLILKSFGLDVRYVWN--------------------------------REDHVWCEYFS--Nf- 220
gi 8347617   179 LLQTRTGRCGEWANCFGLLLAALNLESRFIY--------------------------------DTTDHVWNEVYLlaE-- 224
                         90
                 ....*....|....*.
1GGU_B       371 dlpvgfGGWQAVDSTP 386
gi 4049518   200 -----qQRWVHVDSGE 210
gi 2650741   153 ------NSWVVADPTV 162
gi 74676322  228 -----lNRWVHVDSCE 238
gi 81345627  210 ------KKWRYVDITW 219
gi 259145127 572 ------KEWRFIDVIL 581
gi 19114473  586 ------NEVRLIDASF 595
gi 16329385  247 ------GQWYLLDTTW 256
1X3Z_A       221 -----lNRWVHVDSCe 231
gi 8347617   225 ------QRWCHVDPCe 234
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap