Conserved Protein Domain Family
Dcm

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COG0270: Dcm 
Site-specific DNA-cytosine methylase [Replication, recombination and repair]
Statistics
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PSSM-Id: 223348
View PSSM: COG0270
Aligned: 63 rows
Threshold Bit Score: 142.956
Threshold Setting Gi: 15838375
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
13477024  23 LDNRMTIVLFAGMGGGC-DGLEDAG----FHVHVAINHDPVAVAVHEKRHQH----TRHLRCDVFEADPRKVTGGr-GVR 92  Mesorhizobium loti
16127856   4 NGQRRFLEFFAGGGMAR-LGLGADW-----ACAFANDFDPVKAATYRANFADa--gKHFQEGDVFALSAERLP----DAD 71  Caulobacter crescen...
17545588   2 GAYYNEIDPYAAAWLRNlIAAGHIApg-dVDERDIQDVRPEDLRGYKQHHFFa--gVGVWSLALRRAGWPD------DRL 72  Ralstonia solanacearum
15901190   1 --MIWVLDLFAGIGGFR-MGMEAQG----HECLGFCEIDKFARKSYKSIFQTe---GEIEFHDIRDVSDDEFKKLrgKVD 70  Streptococcus pneum...
730347     4 TKRLRVLELYSGIGGMH-YALNLANi--pADIVCAIDINPQANEIYNLNHG-----KLAKHMDISTLTAKDFDAF--DCK 73  fission yeast
15675067   1 ---MKFLDLFAGIGGFR-LGLINQC----HECIGFCEIDKFARQSYKAIYETe---GEIEFHDIRQVTDQDFRQLrgQVD 69  Streptococcus pyoge...
15838375  14 AAPLLYGSVCSGIEAVS-LAWQPLG----LEAAWFAEIEPFPSAVLAHRYP-----RVPNLGDMTAIARQVRAGtvpAPD 83  Xylella fastidiosa ...
17233286   1 --MKSVLSLFSGIGGLChHGIAAAGlshkFQVKQFVEISPYSQSQLRHEQPq----TPIH-SDITTYNCHRG-----QFD 68  Nostoc sp. PCC 7120
17233385   1 --MKSILSLFSGIGGLChHGIAAAGlshkFQVKQFVEISPYSQSRLRHEQPq----TPIH-SDITTYHCHRG-----QFD 68  Nostoc sp. PCC 7120
13476615   5 PEHIDILSLCTGGAGLD-LGVELAIp--sARTVCMVEREAFAVAHLVSAMEQgllhPAPIWSDARTFDGRAWRG---CVD 78  Mesorhizobium loti
13477024  93 ALHASPDCTHFSVAKGSKPVSKRRRSL--AWVICRWAGTVRP------ETITMENVQEITTWgpliakrdpatgrvlrld 164 Mesorhizobium loti
16127856  72 LAWASSPCQDFSLAGARAGLAGGRSSA--FFGFWSLMRSLSAegr-apSVIVIENVVGLLTSh----------------- 131 Caulobacter crescen...
17545588  73 VWTGSCPCQPFSQAGKGLAFADERHLW---PAWYHLISECRP------AVVLGEQVASNNADt----------------- 126 Ralstonia solanacearum
15901190  71 VICGGFPCQAFSIAGRRlgFEDTRGTL--FFEIARAAKQIQPr------FLFLENVKGLLNHd----------------- 125 Streptococcus pneum...
730347    74 LWTMSPSCQPFTRIGNRKDILDPRSQA--FLNILNVLPHVNNl----pEYILIENVQGFEES------------------ 129 fission yeast
15675067  70 IICGGFSLVKHFHS--QadDWDLRALG--ELSSLRLLERPNR-------------------------------------- 107 Streptococcus pyoge...
15838375  84 ILVGGTPCQSFSVAGSRRGLDDPRGALslAYELANAIDQIRHqdrrspATLVWENVPGVLNDrsna-------------- 149 Xylella fastidiosa ...
17233286  69 IVCGGFPCAGTSNSGNRQGLTDPR-----------------P------AIALIENPTGLLYR------------------ 107 Nostoc sp. PCC 7120
17233385  69 IVAGGLPCQGTSNAGNRQGLDDPRSAL--WAEQFRIIESDRP------AIALIENPTGLLYR------------------ 122 Nostoc sp. PCC 7120
13476615  79 GLVGGIPCQPHSLAGKRLGEGDERD----LWSTARRIIVQSGc-----WFVLIENVGGMLSS------------------ 131 Mesorhizobium loti
13477024 165 gsvagkgervpvqeqwlipdpahKGRIWRAWLKHLRGLGYS-------------FEYRVLVCADYGVPTIRKRFFGVAQA 231 Mesorhizobium loti
16127856 132 -----------------------gGADFTALCQALHEEGYR--------------FGALEIDAGAFVPQSRPRVFVVATR 174 Caulobacter crescen...
17545588 127 --------------------------WIDLVQDDMEAVGHA-------------FGAVPFPAAGVGAPHIRDRLYWVAYA 167 Ralstonia solanacearum
15901190 126 -----------------------KGRTFTTILTTLDELGFD-------------VEWQVLNSKDFGVPKNRERVFIIGHS 169 Streptococcus pneum...
730347   130 -------------------------KAAEECRKVLRNCGYN-------------LIEGILSPNQFNIPNSRSRWYGLARl 171 fission yeast
15675067     --------------------------------------------------------------------------------     Streptococcus pyoge...
15838375 150 --------------------fghFLGALAGESRALQPPGDRwahagcvsgprrrIAWRVLDAQYFGVAQRRKRVFLVASG 209 Xylella fastidiosa ...
17233286 108 --------------------------GLDQIICDLDSIGy-------------mGGWNCISAQQVGLPHERKRIFII--- 145 Nostoc sp. PCC 7120
17233385 123 --------------------------GLEQIICDLDSIGy-------------mGEWNCISAQQVGLPHQRKRIFII--- 160 Nostoc sp. PCC 7120
13476615 132 -------------------------GGAERVWRDLRRLGFE-------------VEGGLFTAKEVGASHERERFFLLGVA 173 Mesorhizobium loti
13477024 232 DGrpivwpvrthaprkdakrlglkpwvgahtIIDWSLPVKsifgrkKPLAEATLRRTARGVMRyvvdaakpfivpithag 311 Mesorhizobium loti
16127856 175 NPpgd-----------------------lvgSSAFHTRAVreaaarLPADLQASWVWWGAPSPpa--------------- 216 Caulobacter crescen...
17545588 168 DGs---------------------------rSRRYSRAVR------RAKAEINREGSEDG-------------------- 194 Ralstonia solanacearum
15901190 170 RKkgtrllfpfrregqatnsetlkalgnlnpSRSGMSGKVyyseglAPTLVRGKGEGFKVAIPcmtp------------- 236 Streptococcus pneum...
730347   172 -------------------------------NFKGEWSID------DVFQFSEVAQKEGEVKRi---------------- 198 fission yeast
15675067     --------------------------------------------------------------------------------     Streptococcus pyoge...
15838375 210 GDdldpaevlferagllgdscagrapwqeaaHDAGPGAEAagacagLAGFAGLKQPYGKVTTTfgfsggigpvdvaaclm 289 Xylella fastidiosa ...
17233286     --------------------------------------------------------------------------------     Nostoc sp. PCC 7120
17233385     --------------------------------------------------------------------------------     Nostoc sp. PCC 7120
13476615 174 DAgrlcle-----------------rwrtagDLVVAASARkiqgqkRQRHGPAAGNGGEVVADag--------------- 221 Mesorhizobium loti
13477024 312 ddrvhdaaeplrtlttahrGEMSVVAPALIRTDQHSAAARngvhsvdepintlhtSSGLAVLGATVVGAGGRAAQSAPRD 391 Mesorhizobium loti
16127856 217 ------------------rNTDLASMLEPDDRAVWNPPERtaall------almaPSHRAAVEARRAGRERAVGAVFRRM 272 Caulobacter crescen...
17545588     --------------------------------------------------------------------------------     Ralstonia solanacearum
15901190 237 ---------------drldKRQNGRRFKENQEPMFTLNTQdrygi------vvvgDLPTSFKETGRVYGSEGLSPTLTTM 295 Streptococcus pneum...
730347   199 -------------------RDYLEIERDWSSYMVLESVLN---------------KWGHQFDIVKPDSSSCCCFTRGYTH 244 fission yeast
15675067     --------------------------------------------------------------------------------     Streptococcus pyoge...
15838375 290 aagpkhdirtetfmvqsvaGSIAHTLDTANNGKGSSEDGTgkgvp------iiafTAQGSGADATLDLTPTLRAGGHRNS 363 Xylella fastidiosa ...
17233286 146 -------------------------------------------------------AYPNGLFNSQQPTPWTNQIRNH--- 167 Nostoc sp. PCC 7120
17233385 161 -------------------------------------------------------AYSNGLFNQVVPAPWSNQIGNH--- 182 Nostoc sp. PCC 7120
13476615 222 ------------------rARRPEGTEDVRRRQYQLAGGGq--------------DLEHSKGLRWREGWAETGVRGGRNA 269 Mesorhizobium loti
13477024 392 MLeplgtttgkedrvlvAATLVDTAHGEgmgrgvsewslddPLRTVGasggkavvaasliqsgygeregqaprvldleep 471 Mesorhizobium loti
16127856 273 RGg-------------eQRAEVRFDGLA-------------GCLRTPrg------------------------------- 295 Caulobacter crescen...
17545588     --------------------------------------------------------------------------------     Ralstonia solanacearum
15901190 296 QGg-------------dKIPKILIPEPI-------------QFLKVReatkkgy-------------------------- 323 Streptococcus pneum...
730347   245 LVq-------------gAGSILQMSDHE-------------NTHEQF--------------------------------- 265 fission yeast
15675067     --------------------------------------------------------------------------------     Streptococcus pyoge...
15838375 364 HAnagvvpaiafaqnnrGEVRFESGHGQ-------------VACTVLsngkpgygvpmvacvslrgreqgl-aaelggtv 429 Xylella fastidiosa ...
17233286 168 -----------------------IEEVR-------------LSLETR--------------------------------- 178 Nostoc sp. PCC 7120
17233385 183 -----------------------ITQVR-------------LSLETR--------------------------------- 193 Nostoc sp. PCC 7120
13476615 270 IGg-------------aDTAMAHAAIER-------------VGPVSIr-------------------------------- 291 Mesorhizobium loti
13477024 472 agtqvggskaalmaaFMAQHNTGEPGRSAEdplstivtlgstqgVVAATLGNLHGTnadgrpivePLATICAGgshahli 551 Mesorhizobium loti
16127856 296 -------------gsSRQTLLVIDGGEVRSr------------lISPREAARLMGL---------PDSYQLPK------- 334 Caulobacter crescen...
17545588     --------------------------------------------------------------------------------     Ralstonia solanacearum
15901190 324 ---------aqaeigDSINLERPSSQYRRGr------------vGKGIANTLTTSG---------QMGVVVASy------ 367 Streptococcus pneum...
730347   266 -------------------ERNRMALQLRY--------------FTAREVARLMGF---------PESLEWSKsn----- 298 fission yeast
15675067     --------------------------------------------------------------------------------     Streptococcus pyoge...
15838375 430 agalrisgggadkpyVLAPDFEAHFRYDWNdpgpgdwshwrvrrLMPVECERLQGM---------PDDYTLIPyrg---- 496 Xylella fastidiosa ...
17233286 179 ------------------SYQPGISKVASR--------------ISIGVAKNIPGN---------YDARRAYGl------ 211 Nostoc sp. PCC 7120
17233385 194 ------------------SYQPGISKVASR--------------IPIGVAKNIPGN---------YDARRAYGl------ 226 Nostoc sp. PCC 7120
13476615 292 --------------sRRQVKADTHADRPGLfp----------pgPTDIEAWRNVLGrap---qlePAVRRMADgv----- 339 Mesorhizobium loti
13477024 552 lgflqhyfgsgkQDDDVRQPLGAlt--gKARYGLVEVMVKGVRHYIDDIG 599 Mesorhizobium loti
16127856 335 ------------SQTAGLQVMGD-----GVAVPVVRWLAETLLVPLVDSK 367 Caulobacter crescentus CB15
17545588     --------------------------------------------------     Ralstonia solanacearum
15901190 368 -----------eGEDKQVYQVAGvlidgQFYRLRIRRITPKECFRLHGFP 406 Streptococcus pneumoniae TIGR4
730347   299 -----------vTEKCMYRLLGN-----SINVKVVSYLISLLLEPLNF-- 330 fission yeast
15675067     --------------------------------------------------     Streptococcus pyogenes M1 GAS
15838375 497 ---------kpaADAPRYKAIGN-----SMAVPCMAWLGQRLVQYLHKTG 532 Xylella fastidiosa 9a5c
17233286 212 ------------SCSPRQAAVAW-----KRIDYLCSLLFEKEAS------ 238 Nostoc sp. PCC 7120
17233385 227 ------------SCSPRQAAVAW-----KRIDYLCSLLSYQEAS------ 253 Nostoc sp. PCC 7120
13476615 340 -----------aARVDRLRMLGN-----GVVSLEAAYALRTLATRLAGQG 373 Mesorhizobium loti
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