1HYQ_A 1 MVRTITVASGKGGTGKTTITANLgVALAQLGHDV-TIVDADITMANLELILGMEGLPVT--LQNVLAg-EARIDEAIYVG 76 Archaeoglobus fulgidus 15594706 1 -MIIIPVASGKGGVGKSLFSTNI-AICLANEGKSvLLVDLDLGASNLHSMLNIIPKKS---IGTFLKt-RINFSDIIIQS 74 Lyme disease spiroc... 15595071 1 MTKIIPVASGKGGVGKTSFVANV-GYKLSSLGKTvILVDLDLGGSNLHTCLGVKNKGVG--IGSFINkkSKSFSDLVCKT 77 Lyme disease spiroc... 15614999 22 QGKVIAVVSGKGGVGKSNVSLNF-ALTLSRQNQKvALIDLDLGMGNLDILMGLSPSYH---IIDMIKr-ELTIWDIAEQG 96 Bacillus halodurans 732146 30 KAKTLAVISGKGGVGKSNITLNM-ALALQDKGKKvLLIDLDIGMGNIDILIGNSSSAT---IIDVLTd-RKPLLQSLSVG 104 Bacillus subtilis 15895414 23 RPVIITVTSGKGGVGKSNFVVNL-SITLQQMNKKvLIFDADVGMGNDDILLGCISKYS---VFDVIYn-NMKIEDAIVEG 97 Clostridium acetobu... 15643668 12 EPNIISVLSGKGGVGKSVIAVNL-SLALKEKGLRvLLLDADVGFGSVEILLGFMAPKT---LKDFFKs-NVRIEDIVFET 86 Thermotoga maritima 15639839 1 -MQIIPIASGKGGVGKSLLAANL-SIALGQAGKKvVVADLDLGASNLHLALGQKGNKHG--VGTFLMg-ASSFEEIMVPT 75 Treponema pallidum 17229525 1 MSQIIAIHSFRGGTGKSNIIANI-AATMALQGQRvGIIDTDIQSPGIHIIFGLKEEKIQltLNDYLWq-RCDIQDTAYDV 78 Nostoc sp. PCC 7120 17230289 1 MSKIIAIHSFRGGTGKSNLTANL-AVAMALQEKRvAIVDTDLQSPGIHALFGIDKTITGktLNDYLWn-RSCIEDTACDV 78 Nostoc sp. PCC 7120
1HYQ_A 77 P--------------GGVKVVPAGVSLEGLRKANPEKLEDVLTQIMEST-------DILLLDAPAGLERSAVIAIAAAQE 135 Archaeoglobus fulgidus 15594706 75 Gi-------------KNLNFIAGDSDIPELANIAASQKKIIIKNLKSLKy------DYLVIDLGAGTAFNIIDFFLMSKR 135 Lyme disease spiroc... 15595071 78 Sy-------------DKLYLIPGDALYTGTANLPFSIKKKIIESIQKDLi-----aDFIFLDLGSGTSYNTIDFYLASYS 139 Lyme disease spiroc... 15614999 97 P--------------EGITYIAGGSGLSELVELNERQMERFFQQLESLGai----yDYIILDMGAGATAESLRFILSAHE 158 Bacillus halodurans 732146 105 P--------------KGLRYISGGTGLDVMFQLDQRKWTFFANELSHALsq----fDYVLFDMGAGLSKDQLPFILSAED 166 Bacillus subtilis 15895414 98 P--------------FGVKLLPGGSGITKFKDITEDQINAFVKKLASIGn-----fDYIIMDTGAGVNRSVLGFISCCEE 158 Clostridium acetobu... 15643668 87 K--------------YGVDVLSSGIDMEDLILFNLGDRRRFFDEFARLLrk----yDYLVIDFPPGYNENLDQFYIQSDF 148 Thermotoga maritima 15639839 76 Gy-------------PNVYLVPGDSEIPGFAALKVSQRRALTVGLLKTHa------DYVVLDLGAGTHLGVLEFFLLSSR 136 Treponema pallidum 17229525 79 TdtlvtepgnttkvkGSLYLIPSSIKAAEIARILREGYDVVRLNDGFQElirslklDYLLIDTHPGLNEETLVSIGISNV 158 Nostoc sp. PCC 7120 17230289 79 Tshla-------isqGTVFLIPSSINADEIAKILSEGYNVSLLNTGFQRlikelklDYLFIDTHPGLSRETLLCIAISDL 151 Nostoc sp. PCC 7120
1HYQ_A 136 LLLVVNPEISSITDGLKTKIVAERLGTKVLG------------------------------------------------- 166 Archaeoglobus fulgidus 15594706 136 GVIVTTPTVTATMNAYLFLKNIIFRLLSSVFkrgtkgneilrtikqnsidlqrvyipnlllklesedpenyskfnklfrt 215 Lyme disease spiroc... 15595071 140 GVIVTIPETPSILNAYSFLKNALYRLLYLGFpqksperdyignffkdkiegtnlgfkdlvvgielislssslkvkrmmnn 219 Lyme disease spiroc... 15614999 159 IFVVTTPEPTSITDAYAMVKYICKEPIENPEi------------------------------------------------ 190 Bacillus halodurans 732146 167 ILIITTPEPTAIMDAYSAVKHLVLTENKLSMk------------------------------------------------ 198 Bacillus subtilis 15895414 159 LIILTTPEPTSLTDAYSLFKAVVHFKIKSYAk------------------------------------------------ 190 Clostridium acetobu... 15643668 149 LILVTSPEPTSIINTYTLIKLLSVKGITPEEi------------------------------------------------ 180 Thermotoga maritima 15639839 137 GIIVTEPAVSAVLNAYLFLKNVVFKMLCAAFkkgtggsiflenlksdaaavqrmyvpkilaelervdqrgvavlldrmrs 216 Treponema pallidum 17229525 159 LLIILRPDSQDFQGTAVTVDVARKLKAA---------------------------------------------------- 186 Nostoc sp. PCC 7120 17230289 152 LIIILRPDRQDFQGTAVTVNIARQLQVR---------------------------------------------------- 179 Nostoc sp. PCC 7120
1HYQ_A 167 ----VVVNRI--TTLGIEMAKNEIEAILEAK--VIGLIPEDP---EVRRAAAYGKPVVLRSPNSPAARAIVELANYIAGG 235 Archaeoglobus fulgidus 15594706 216 ispfMIFNMLkaPKD-IEKTEKIIKSAKNYLsiNLQSIGAIYkdeIVDQALNSKIPITIYKPTSSTSKSIKKIAKKLIEI 294 Lyme disease spiroc... 15595071 220 fyprVVLNRIe-tSEEIAMCENLINVVKNNIniPIEFIGFVPfakSFREAINNRVPFIDFEKNSKLNKYFEFIAGNLIKS 298 Lyme disease spiroc... 15614999 191 ---lLIVNRAesKREGEQTAANFKRVVSHFLkkDIHSLGYLPqdsHVVKAVKAQAPFVLHAPQAKASMAMGKLVHTYLGH 267 Bacillus halodurans 732146 199 ----VAVNRCrdQKEGLDAFARLSRTIHMFLdvQVQFAGSVSddvIVSKAVVEQVPFFIKSPQAKASRSVRILADALFER 274 Bacillus subtilis 15895414 191 ----VVINRVvdNKEGLETYKKFQSVAKKFLkaDTEFLGSISedsRIVKAVRNQTPFVVENPNCYAAKDIQYIANKLMGT 266 Clostridium acetobu... 15643668 181 ---fLVMNMVrnMKEGRLAADRLKRVVERFVgfTIKNYFVIKedqVVQRSVFLQEPFVRSHSRSQPSLAIYGLREKILKE 257 Thermotoga maritima 15639839 217 frprLVMNMIadPKD-VDKALKIRRSCEQYLniTLEYLGVIYqdtQQNVALSSGLPIVVYKPQSLIAQAVYRIADKILQS 295 Treponema pallidum 17229525 187 ----KILLVLnkALPS-LNFSDLKQQVEQIYdvPVAGILPLA---EDMVQLGSKGLFCLRYSQHTITQIIQEITEQIAGL 258 Nostoc sp. PCC 7120 17230289 180 ----EMMMVIn-kIPNRMNFASLQQKVEKTYnvPVAGILPLS---EDMAQLGSSGIFCLQYPDHPFTQTLQKLADKVS-- 249 Nostoc sp. PCC 7120
1HYQ_A 236 AKKKVPAevkekkkEGALAKMLR-IFRR 262 Archaeoglobus fulgidus 15594706 295 EDLTNDAel---lnEEDLNESYDfVLRE 319 Lyme disease spirochete 15595071 299 PIEGSPYi-----yDDIYDMIKDqSRFI 321 Lyme disease spirochete 15614999 268 RVDRGa--------PSYQSFMKKiRKWF 287 Bacillus halodurans 732146 275 EETRHKEd-----kQTFIEKLSSfLMRR 297 Bacillus subtilis 15895414 267 TTKDNG--------LGIEGLFKKlFKIF 286 Clostridium acetobutylicum 15643668 258 PVQK----------KGFLNKIRQmLGIG 275 Thermotoga maritima 15639839 296 EGEEASSie---dyEGLVERSFAsAEAE 320 Treponema pallidum 17229525 259 VVSH------------------------ 262 Nostoc sp. PCC 7120 17230289 ---------------------------- Nostoc sp. PCC 7120
Jiyao W et al.(2023). "The conserved domain database in 2023.",