1G6N,1HW5


Conserved Protein Domain Family
Crp

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COG0664: Crp (this model, PSSM-Id:223736 is obsolete and has been replaced by 440428)
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cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
linked to 3D-structure
Statistics
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PSSM-Id: 223736
Aligned: 178 rows
Threshold Bit Score: 57.9191
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1G6N_B     1 MVLGKPQ----------------------TDPTLEWFL-SHCHIHKYPSK---------STLIHQGEKAET--------- 39  Escherichia coli
15806020  17 YRPGAVIly------------------pgKSDMLYRVSsGLVRVHTMDDDg-------nGLTLRYVKPGEYf-------- 63  Deinococcus radiodu...
19173420  53 ENGTLTKlqlnske---------gdrkgfDEEWRASRRsGVYSERITPETf-------rLNYYPKDEETIRf-------- 108 Encephalitozoon cun...
15599898  17 RLQGIPHrlleg------------lapsgPALELERSDdLERELPADQVFl-------vESGLLHALVDERp-------- 69  Pseudomonas aerugin...
16263031  23 TREKAEQvmrrg------------pwlasMTEPFRTELlRHAHLQKFAPD---------QVVYRHGDAVGG--------- 72  Sinorhizobium meliloti
15639979  96 VNRKDPNflsvstrqefeahasqvvrivdRNRHFLSSRsLVHQAHGHEQGnficdtdsfEITFYASLISSYlyntnrine 175 Treponema pallidum
15642558   7 AYLKQHGf--------------------sDAECAQLQS--VAQPLELPTR---------HVLVAQGETTPF--------- 46  Vibrio cholerae
13488119   1 ----------------------------mSECRMLFIPaNALRKLVVELPn-------fALCLLQGLAAKGr-------- 37  Mesorhizobium loti
13471969  10 PQYRNELlr------------------fmPADDLALLA-PHMQRCALPVR---------MMLVTPNIPIEA--------- 52  Mesorhizobium loti
16330881   6 PIKLNQLlg------------------llPVEAYKRLA-PHLKKVVYKTG---------TVLYEPNEVMEF--------- 48  Synechocystis sp. P...
1G6N_B    40 -LYYIVKGSVAVLIKDEE--GKEMILS------YLNQGDFIGELGLFE-Eg--qERSAWVRAKTA-CEVAEISYKKFRQ- 105 Escherichia coli
15806020  64 -GEEALAGVNRAYFAEAVtdSAIDVINp----aLMSAEDNLVVTTHLVrTleraYESIYRLVGKRlRARIAGELLELKD- 137 Deinococcus radiodu...
19173420 109 -LSSILVSDIPFGFLNPE--QKTRLIEste-liEIKRGTFVMHEGEIGsQmyivASGEFEVTKGG-TLLRKLTKGCFFG- 182 Encephalitozoon cun...
15599898  70 -LFYLQEGDLLGLRRGLElpACRHANE------EPIRLLPYSRDALLQhIhadqERQELLLQYLIgQTALLGDALAHLK- 141 Pseudomonas aerugin...
16263031  73 -MYGLVAGSLTINSAPPD--AASRLIH------LGMPGAWTGEGPFLTgQ----PRRVELRALGG-AWMMHVPLDALEQ- 137 Sinorhizobium meliloti
15639979 176 lERTSFEGAMMELLLNALehGNCGISYdektewLEQRKDIFDLIALRKqD----PRISAKKIYISyDITLQRTRITIRDe 251 Treponema pallidum
15642558  47 -AYWVLAGLCHACYLTEE--GKSFSKEf-----YWEQDWAIGFESLLReQ----ASPFMLETLSP-VQLMGVPIEVLREw 113 Vibrio cholerae
13488119  38 -CYSAMAQMLGTRSVIER--LAQFLMN---------LGSLHGVRDGK-------AIVINAKVTHDqIAAMVGSTRQWVT- 97  Mesorhizobium loti
13471969  53 -VYFIEQGIGSVVASTAS--GHDAEIG------FIGFEGMTGSALVMGdD-----RAAHACFVQLeGEAIRIDAAPFNA- 117 Mesorhizobium loti
16330881  49 -AYFPNTAMISVVSIMED--GSTTEIG------LIGNEGMVGLPIILGgK-----QTTSQVIVQVqGEAWKLSAHILLR- 113 Synechocystis sp. P...
1G6N_B   106 ----------LIQv-----nPDILMRLSAQMARRLQVTSEKVGNL--------------AFLDVTGRIAQTLLNLAKQPD 156 Escherichia coli
15806020 138 ----------TALatqldsgETMIYATHDELAAAVGSVRETVTKVvg----------elSREGVHQRRLRQDHPQGRARP 197 Deinococcus radiodu...
19173420 183 ----------EIAllhniprTATVKAVTDGKVWVVEQTSFSGIRM--------------VDRILNKKIVLEGLREHRVFP 238 Encephalitozoon cun...
15599898 142 ----------QPEvr---paTGFRHFAAGEALIRQGDDADHVFIIie-----------gHAEALVDGQKVGDVQKDEIFG 197 Pseudomonas aerugin...
16263031 138 ----------MMArd-----pGVSRAIAMNTVFTVDVLLRIIHDL--------------QKRAVGRRIASVLQRASWVGD 188 Sinorhizobium meliloti
15639979 252 gtgfdwksrmASAckp--glHGMGIKMTEIFVKRLSYNDVGNEVTfeidnqenvanlvpSILKNQQVLTFRDAQVVCYQN 329 Treponema pallidum
15642558 114 ----------rSSgh-----pLYQRLLETQLLYKEQKERFMLLYR--------------PEQRYQVMCTQFPDLMAR--- 161 Vibrio cholerae
13488119  98 ----------MMMk-------rFQKEGLVTVTPRHIRIERPHT----------------LMEMVSKRAAG---------- 134 Mesorhizobium loti
13471969 118 ----------ALAas-----pTLRLFLLHFVNTLHTQTGCTALVN--------------ARLKLEERLARWLLMCDDRVP 168 Mesorhizobium loti
16330881 114 ----------EFEqs-----pQLQRILLLYTQARLTQVSQSAACN--------------RQHKIEERLARWLMSVHDCLQ 164 Synechocystis sp. P...
1G6N_B   157 AMTHPD----GM--QIKITRQEIGQIV--GCSRETVGRILKMLEDQNLISAHGKTIVVYGTR 210 Escherichia coli
15806020 198 RHHRGGl-------KLSTLPLTAPTPAv-GVFAARTELPVPGFSCLGTLFFGDGAALCEFRR 251 Deinococcus radiodurans
19173420 239 LFRDEDyervLN--SLSFVYYKKGSRVe-VKSSEFLMSLFDGEVDDGEVRKIKAKEIISKGF 297 Encephalitozoon cuniculi
15599898 198 AMAVFTrekrSA--TVVASEPCTVMVIp-KEQFLGLMQNNPRIAHSLIEGMARRIDLLNREV 256 Pseudomonas aeruginosa PA01
16263031 189 MP-------------IPLSQTDLGIMA--NASRQQVNTAMQRFARAGWVSYTYRSVTVSNSQ 235 Sinorhizobium meliloti
15639979 330 EESSSLfyisSGkfAVYVDNKFMSMLTpsDIFIGEMSFLLNNRRSATIVSVGEGTLVKISKM 391 Treponema pallidum
15642558 162 -----------------LCDHHIAAYL--GITPISLSRIKARLRQDA--------------- 189 Vibrio cholerae
13488119     --------------------------------------------------------------     Mesorhizobium loti
13471969 169 GE------------SLAMTHEFLSIML--GVRRPGVTVALQLLEGRALIRSRRGEIVIRDRA 216 Mesorhizobium loti
16330881 165 VD------------EIPLTQEFVANML--GVRRSGVTIAANSLQQSGMITYRRGKITLLDYD 212 Synechocystis sp. PCC 6803
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