Conserved Protein Domain Family
Tas

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COG0667: Tas 
Predicted oxidoreductase (related to aryl-alcohol dehydrogenase) [General function prediction only]
Statistics
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PSSM-Id: 223739
View PSSM: COG0667
Aligned: 153 rows
Threshold Bit Score: 50.0187
Threshold Setting Gi: 13488412
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16127892  52 MEYAKLGR-SDVMVSRCCLGTMTWGSqnTEAEAHE--QMDYALSRGVNFWDTAELYASPpnpetqgLTETYIGSWLRKTG 128
gi 5902702    1 ------------------------MGs--MNKEQAfeLLDAFYEAGGNCIDTANSYQNE-------ESEIWIGEWMKSRK 47
gi 1175960   24 SAGIRVSp-LILGGMSIGDAWSEILGs--MSKERAfeLLDAFYEAGGNFIDTANNYQNE-------QSEAWIGEWMVSRK 93
gi 1175961      --------------------------------------------------------------------------------
gi 1352946    1 ---------------------------------------------------------------------------MASRK 5
gi 1176577   24 TAGIRVSp-LILGGASIGDAWSGFMGs--MNKEQAfeLLDAFYEAGGNCIDTANSYQNE-------ESEIWIGEWMASRK 93
gi 6324408      --------------------------------------------------------------------------------
gi 16799950   6 VQGRKNGKqIEIACSNLVMGAGDFLR--ADNMDFAgpILDQYFEMGGNIFDTARHYR---------HSEKAIGTWMKARG 74
gi 13488551   1 MKQVFVEa-IGSKVSSIGFGCASLGSr--IGARQGieTLERAYEAGVTWYDVAPSYGDG-------MAESIWG-EFASRK 69
gi 13475622   1 MKMVFVEa-IGSKVSSIGFGCASLGSr--IGARQGieTLERAYEAGVTWYDVAPSYGDG-------MAESIWG-EFASRK 69
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16127892 129 kRSEIVLASKVAGQGAafgglpWLRKDg-------aVTRQTKAQIDEAVEGSLRRLGTDYLDLYQLHWPDRrvrvfggqt 201
gi 5902702   48 lRDQIVIATKFTGDY-------KKYEVgggksanycGNHKHSLHVSVRDSLRKLQT--DWIDILYVHWWDYmssie---- 114
gi 1175960   94 lRDQIVIATKFTTDY-------KKYDVgggksanycGNHKRSLHVSVRDSLRKLQT--DWIDILYVHWWDYmssie---- 160
gi 1175961      --------------------------------------------------------------------------------
gi 1352946    6 lRDQIVIATKFTTDY-------KGYDVgkgksanfcGNHKRSLHVSVRDSLRKLQT--DWIDILYVHWWDYmssie---- 72
gi 1176577   94 lRDQIVIATKFTGDY-------KKYEVgggksanycGNHKRSLHVSVRDSLRKLQT--DWIDILYIHWWDYmssie---- 160
gi 6324408      --------------------------------------------------------------------------------
gi 16799950  75 nRDSVIIQTKGGHPVR-------EASD---------VPRVTAEAIHEDISVSLDTLQTDHVELFALHRDNP--------- 129
gi 13488551  70 r-DRVCVCTKVGMRP-------PNTPTamrllkplsRMAIAVVPALKQYASRVRPTPFKVPLSAELIRSSVeeslg---- 137
gi 13475622  70 r-DRVCVCTKVGMRP-------PKTSAtmrllkplsRIAVATVPALKQNASRVRPAPFKVPLSAELIRSSVeeslg---- 137
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16127892 202 ykdyslefER-FGDILLALDAHVKKGAIRHVGVSNEFPWGVMRFLSESdtrglPRIASIQNAYHLAN--R-TFEYG---- 273
gi 5902702  115 -------evmdSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKT------PFSIYQGKWNVLN--R-DFERD---- 174
gi 1175960  161 -------evmdSLHILVQQARSSIW-----------VC------------------------------------------ 180
gi 1175961      --------------------------------------------------------------------------------
gi 1352946   73 -------evmdSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKT------PFSIYQGKWNVLN--R-DFERD---- 132
gi 1176577  161 -------evmdSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSHGKT------PFSVYQGKWNVLN--R-DFERD---- 220
gi 6324408      --------------------------------------------------------------------------------
gi 16799950 130 --------EVeVGEIMEAMHQEVEEGRVYAIGLSNWELPRIIEANEYAvshglTPLSFNSPNFSLAKvnRpRWENCvsan 201
gi 13488551 138 -------rlrtDYVDVLALHRATAEELVRED--IIRAVERVVQDGKAR------AISVAGDLEAGMT--A-LKESL---- 195
gi 13475622 138 -------rlrtDYVDVLALHRPTAEELVRED--IIRAVERVVQDGKAR------AISVAGHLDAGMT--A-LKESL---- 195
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16127892 274 --LAEIAMREQVGLLAYSPLAQGQLTGKYLDgalPAGSRKAL---YNRMQRYEGPGAIEAFRNYVDLA-RAHGLDPAQLA 347
gi 5902702  175 --IIPMARHFGMALAPWDVMGGGRFQSKKAM---EERKKNGEglrTVSGTSKQTDKEVKISEALAKVAeEHGTESVTAIA 249
gi 1175960  181 -----LIRLPGLFLRQITTLN---LMVKPLL---ASIKVNGTc------------------------------------- 212
gi 1175961    1 -----MARHFGMALAPWDVMGGGRFQSKKAM---EERRKNGEgirSFVGASEQTDAEIKISEALAKVAeEHGTESVTAIA 72
gi 1352946  133 --IIPMARHFGMALAPWDVMGGGRFQSKKAV---EERKKKGEglrTFFGTSEQTDMEVKISEALLKVAeEHGTESVTAIA 207
gi 1176577  221 --IIPMARHFGMALAPWDVMGGGRFQSKKAM---EERKKNGEglrTFVGGPEQTELEVKISEALTKIAeEHGTESVTAIA 295
gi 6324408    1 -----MARHFGMALAPWDVMGGGRFQSKKAM---EERRKNGEcirSFVGASEQTDAEIKISEALAKVAeEHGTESVTAIA 72
gi 16799950 202 etMIHWHKKTGLPLFSWSSQAGGFFSGRFSK-----EDRSDT----EMVEVYYSEANWERFSRAKQLA-KQKGCTPIQIS 271
gi 13488551 196 --PYRLVQIANTPLKPNLAKLKARAHRHRTF---VTHGTFSGldrIVAKFNTRKEILAALGDLGYRGSpN---EVAIAFL 267
gi 13475622 196 --PYRFVQIANTPLEPNLAKLKARAHRHRTF---VTHGTFSGldrIVAKFNTRKEILAALGDLGYHGSpK---EVAIAFL 267
                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16127892 348 LKFCDARPFVTATIIGATSMDQLKINIDAFDIA-WTDAL---EKAVDAIHLRHPNPCP 401
gi 5902702  250 IAYVRSKAKNVFPLVGGRKIEHLKQNIEALSIKlTPEQIeylESIIPFDVGFPTNFIG 307
gi 1175960      ----------------------------------------------------------
gi 1175961   73 IAYVRSKAKNVFPLVGGRKIEHLKQNIEALSIKlTPEQIkylESIIPFDVGFPTNFIG 130
gi 1352946  208 IAYVRSKAKHVFPLVGGRKIEHLKQNIEALSIKlTPEQIkylESIVPFDVGFPTNFIG 265
gi 1176577  296 IAYVRSKAKNVFPLIGGRKIEHLKQNIEALSIKlTPEQIeylESIVPFDVGFPKSLIG 353
gi 6324408   73 IAYVRSKAKNVFPSVEGGKIEDLKENIKALSIDlTPDNIkylENVVPFDIGFPNTFIV 130
gi 16799950 272 LAYVLTQSFPTAAVIGPENAAELKSSVLAAEIT-LTQAE---VDWLDLKA-------- 317
gi 13488551 268 ADYAFATNSAGVTLVSMFKKEHLDFNLRRLKSDpTPEHLnavAAALDMGVTDRSTGEP 325
gi 13475622 268 ADYAFATNSAGVTLVSMFKKEHLDFNLRRLKSDpPPERLnavAAALDLDVKD------ 319
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