20089605 124 DLEKGGFVLPGELVGTTEEFKSGAGTTVI--GGDIYSTATGNVLIDRKSRVVSVKPNTL-------------TPNILKVG 188 Methanosarcina acet... 11497822 1 ----MRFVMPGDRIGSAEEYVKGEGVYEE--GGELFAAVAGKLII--KDRVAKVESISP-------------IPEIVKG- 58 Archaeoglobus fulgidus 14600717 7 GVVEKGKVMPGDVLATIEEFLPGEGVYVDpvKGFIRAAAPGVAYLDMSRRIAYVKPHKK--------------PQTPGPG 72 Aeropyrum pernix 20093500 4 YVEPGKFVLPGDKITVAEAFYPGPGTYED--GGVVRAAITGRVEVDLEEREVRVEPYVD-------------TPPKLKRG 68 Methanopyrus kandle... 15679318 2 KVKSGDMVFPGDFLAVSEEVLPSEGTYDE--DGKIKSLVVGEVSRDDRNKSIKVISKLN-------------TPPTLKRG 66 Methanothermobacter... 14520270 10 TIKNGDFVLPGDYLGVIEEYLPGEGVIVE--DGNLYSARAGWVKINKDKVEISLEPASS-------------VPPIPKKG 74 Pyrococcus abyssi 18313005 1 --MKKTIVTPGELVAYAEEFETKGAVLAV--DHKYHASALSVATYDEKSHVAVVKPVRG--------------SAYPQPG 62 Pyrobaculum aerophilum 14589998 10 TIKDGDFVLPGDYLGVIEEYLPGDGVIAE--DGNLYSTRAGWVRINKDKIEISLEPASK-------------VPPVPKKG 74 Pyrococcus horikoshii 19076010 1 ----MNLVLPGQVVARGAP--NGEGTVKR--GDYIISTRTGIFDPEKNSVTYPRKVEET--------------AVLPNVG 58 fission yeast 15897237 1 MRTQGELTLPGEELAVIEEFMTGDGTYEQ--NGIVRAAVVGKIFYDMLNRKSNVLGFKKi------------IFQHLKKA 66 Sulfolobus solfatar... 13541908 1 MQDDKKVAFPGDMIATTEEYLPGKNTEEK--NGEIIAVKFGQIIRDDINLLISVDTQKK-------------EFTLKKG- 64 Thermoplasma volcanium 16081977 1 MEGDKKVAFPGDIIATTEEYLPGRNTEEK--NGEIVATKFGNIVRDDINLMISVDTGKK-------------EFFLRKG- 64 Thermoplasma acidop... 1730832 58 ATLVGTVRCEEEKKTDQEEEREGTDQSTEe-EKSVDASPNDVTRRTVKNILVSVLPGTEkgrktnkyanndfANNLPKEG 136 baker's yeast
20089605 189 DIVYGKITDVRESGAMVEVAGIEGKEn--------------REIVNTRPGDIHVSNVRDSYVKRLS-------------- 240 Methanosarcina acet... 11497822 59 DVVLGRVVDLRNSIALIEVSSKKG-En--------------RGPSNRGIGILHVSNVDEGYVKEIS-------------- 109 Archaeoglobus fulgidus 14600717 73 SEVAALVTGVRGDLVVAEVYGVVRLSpkp---------awlYELPSPYSAAIPISQIADEYIKNIE-------------- 129 Aeropyrum pernix 20093500 69 ASVIGRVQSVKEQVVLVKICFVDDRTd--------------REPPTSGVGGIHISKVRDAYVEDLA-------------- 120 Methanopyrus kandle... 15679318 67 SRVIGEVIDVRGQRALVRIHSIKGNR---------------RALATYFVGGVHVSQARKGYLSKLT-------------- 117 Methanothermobacter... 14520270 75 DIVYARVIDVKQQAVLLRMIKIEGQEn--------------REIATSKLAGIHISQVKDGFVEDLR-------------- 126 Pyrococcus abyssi 18313005 63 AVVYCQVTGKGRRAYQLRCFAVEEGK---------------------NAADLKYPVSGVLPYFFSD-------------- 107 Pyrobaculum aerophilum 14589998 75 DIVYARVLEVKQQAVLLKMIKIEGQEg-------------nREIATSKLAGIHISQVKDGFVEDLR-------------- 127 Pyrococcus horikoshii 19076010 59 SIVLARVSRINARQATVNISVVDDVC-----------------TKDEFQGVIHVQDIRATEKNKVKv------------- 108 fission yeast 15897237 67 KYVIGIVNSIKEDSALVSIVGIEE-----------------RGLASPISAYLHISQISNKKINNVT-------------- 115 Sulfolobus solfatar... 13541908 65 DIVYGQVVKGEQHRYIVRIVGAFQKG---------------LG---LREIDEEMQLSLGIARRPQS-------------- 112 Thermoplasma volcanium 16081977 65 DVVYGQVIKNDAHRYIVRVVGVFQRG---------------TG---LKEVDEEMQLSFGMSRRPQS-------------- 112 Thermoplasma acidop... 1730832 137 DIVLTRVTRLSLQRANVEILAVEDKPspidsgigsngsgivAAGGGSGAATFSVSQASSDLGETFRgiirsqdvrstdrd 216 baker's yeast
20089605 241 -----DEFRPSDIVKARVIDV---DRMRLTTSEDSLGVVKAYCSNCRGELVL--EGKKLKCPVCNMTETRKISTEYGKGI 310 Methanosarcina acet... 11497822 110 -----EAVGYLDILKARVIG----DNLRLSTKEEEMGVLRALCSNCKTEMVR--EGDILKCPECGRVEKRKISTDYGKGE 178 Archaeoglobus fulgidus 14600717 130 -----DYYRMGDWILAKIVSRt--PPFTLSTVEPRYGVVYAICSRCGAVMEFq-SERSMKCPKCGNVEKRKVSIHAKSRH 201 Aeropyrum pernix 20093500 121 -----DEFQPGDIVRARVVSTk--MPVQLSTVGKEYGVVLAYCTRCRSELEKv-KGRTLRCPVCGHTETRKVAAGYLREA 192 Methanopyrus kandle... 15679318 118 -----DAFRIGDIVEARVTKImglDGIDLQTSGRDLGVIKAMCTRCRHFMEVn-GRDEVRCPNCENREKRKLSVNYEG-- 189 Methanothermobacter... 14520270 127 -----NEFKIGDIVRARVIADe-kSPIQLTTKDPDLGVVYALCSKCRTPLVR--KGNQLVCPRCGNVETRKISTLYRKVK 198 Pyrococcus abyssi 18313005 108 -----GDIGIGDYLRAKVVSTy-gPPIVVSIRGPTYGVILSRCPKCGAVLKR--RGMMLYCPNCGAEVKRKIAVGHYAT- 178 Pyrobaculum aerophilum 14589998 128 -----NEFKVGDIVRARVIADe-kSPIQLTTKDPDLGVVYALCSKCRTPLVR--KGNQLVCPKCGNVETRKISNLYRKVK 199 Pyrococcus horikoshii 19076010 109 ----qNSFRPGDIVRALVISLgdgSSYFLTTARNDLGVIFAQSSETGEQMFP--VDYQHMQTKSGYTEMRKCAKPILDE- 181 fission yeast 15897237 116 -----DAIKIGDVIKAKLLSYt--FPLALTIKMKDLGVIYARCSRCGYLLIKq-DENNLKCQRCGNIEQRKIGSYMVKKG 187 Sulfolobus solfatar... 13541908 113 -----DFIAIGDLIRGYVIRTg--DFPEISINGNHYGVISAVCLRCRQPLVK--RGITLYCENCQRTEIRKMADDYGNVD 183 Thermoplasma volcanium 16081977 113 -----DFVAVGDLIRGYVVRTg--DMPEISINGNHYGVISAVCSRCRQPLVK--KNITLYCENCQRTEIRKIADDYGSVD 183 Thermoplasma acidop... 1730832 217 rvkviECFKPGDIVRAQVLSLgdgTNYYLTTARNDLGVVFARAANGAGGLMYatDWQMMTSPVTGATEKRKCAKPF---- 292 baker's yeast
20089605 311 R 311 Methanosarcina acetivorans C2A 11497822 179 W 179 Archaeoglobus fulgidus 14600717 202 L 202 Aeropyrum pernix 20093500 193 E 193 Methanopyrus kandleri AV19 15679318 - Methanothermobacter thermautotrophicus str. Delta H 14520270 199 L 199 Pyrococcus abyssi 18313005 - Pyrobaculum aerophilum 14589998 200 I 200 Pyrococcus horikoshii 19076010 - fission yeast 15897237 188 G 188 Sulfolobus solfataricus 13541908 184 I 184 Thermoplasma volcanium 16081977 184 I 184 Thermoplasma acidophilum 1730832 - baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",