Conserved Protein Domain Family
YebA

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COG1305: YebA 
Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 224224
View PSSM: COG1305
Aligned: 74 rows
Threshold Bit Score: 43.5039
Threshold Setting Gi: 11499934
Created: 7-Oct-2002
Updated: 23-Jan-2015
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17227599 291 YGFNNQINQNLRGEMKPKVVMRVRSQAEGFWRV-LAFDRYTGKGWDISRNDDv--TTLRRSPWSYQIYLSPPPISGKTRE 367
gi 11499934   1 ---------MQPKKLVIILLILFCTFIIYNFFTiWYYLIIAPVGESEIKKIVeevNSTSGTYQKLEKIAKWEGENIAYIY 71
gi 11499976  13 ISVSLLSSFISSLDFSKTGFEGLIGKGDFGGGN-SAGVQYPQYSTTQGEVFGg--EGSGGGFASLSDSSSTFNPPNVPLF 89
gi 15895675   9 ILVFLFLFPIARGFLFKFSSYDLKRDTENLINSiSFIVAIFIGIRYYKVIFLn--YENSKIYKFIPSEISSILASKPYIL 86
gi 20093743   1 ------------------MSMLNAEPKWFQWVEgCDWAKYLATRDTPIVDWTgelIGENWRANWVRAAKYILYCAPYKGD 62
gi 15597240  60 ILKPSGREMLSRIDRSYAETDSLIVEKAELTQPgGKPVPLDQSQIDTRTAPNpdqGFLRERQTSLAFPNLRVGTRISYTL 139
gi 14520509  25 SSTVSCILLLKSGETKPRKKKKRKRGGESIKMSpKTSKPLKATPKYVLRKFMrvtIKILMAYVALSLVLIAIPHAYKFIW 104
gi 18313054  36 SGFSASPPPAVSVSSGLYFKTYINARGTGGVMY-LRCYVYDVYLSGSWIYEGs--GGSSFGDGVVTVGPGPFKFGGEVNL 112
gi 15606327     --------------------------------------------------------------------------------
gi 16802033 162 RNQFFRWIYSAPNSYWAYGKYRFELKNETGQNLeTNFHYFRDEAGAILDKEK---VIIENSQSYTIEKEDYIGNDPKEFE 238
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17227599 368 VVQ-TYTVVSDLPNLIPAMSYPREVYFPTPMIAVDKegglrap----vglsedLTYTVISDVPYRDRtllgkat--ndyp 440
gi 11499934  72 GINpNFSIPSYHFYWINGELKIRALENSGFNGDPRWiay------------fkVGGCGELARLFCEAak----------- 128
gi 11499976  90 FVEgLNPETNYLRLYTATRYENGKWVEDKGDCSQESi---------------pIARKFKLTPIVELN------------- 141
gi 15895675  87 YFIiIPIFVYIVYKLISVVLNLIARYTFFNIYDVLDriisnksntvkriigavVQVPRAVCYLVTVLfllnava--iinp 164
gi 20093743  63 SVEkVRQAWYGSITLEGHVPDKGAPAKFGEVDWSDK------------------RPDMRYIGLAFDYfd----------- 113
gi 15597240 140 REHfTAKPLSTQFHYILSRPPMPVRDDRFVAEFKAErpifvrse--lmdayriEQSADKKTLKVSLKkpqytn-----yi 212
gi 14520509 105 GDKiTSEVLSKVSSNTTDPKELALRIYSWEQQNFANpyfiq-------penmsLIEKLLAGYGFYYDkqgevhlfrpfni 177
gi 18313054 113 SAPlMGGCVPLATPAVDGLVLGGFKVAAPGARLAADleglyvs----faggllSHIVSYIGEGAAPGr------------ 176
gi 15606327     --------------------------------------------------------------------------------
gi 16802033 239 LTPfIDFVTEKTYPEITKAISDVYQKFYQVDLASFAgdlvsel----dalpslKHKIRHAIDFVQKEiyylynetemdgh 314
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17227599 441 lniKNYYLQIPPEIASKv-----------KQRTEEILANynqk--qvgqSEKALTSSYEKALYLAQYLK-QNYSIPENPl 506
gi 11499934 129 ----rAGFEARVVSDLGy-----------DHAWVEVKINns-------wVVADPTVYWLYVNYPEKYPNwNKLWFNNES- 185
gi 11499976 142 -----RYLPVSKDTKG-------------ILPVGENIER----------CYNAATGTFRINATRSPYYG-FTTAKSFKP- 191
gi 15895675 165 smkINSYLKDSKAYNYLc-----------KRIIIPVTNSsvak--sfpnILDNSFKIVTKTDSLNKVGNaLKNDDNASN- 230
gi 20093743 114 --pVFDFLHVPEDLRRT------------MRRLAELMVG------------LGKVSEREYAESILKDEYmPPRSGEPSR- 166
gi 15597240 213 neaGNAYLRHTPRLELGssldlqdnfgpfAARYNEILAAelpkgaaaavAAVKGKPAREQVAGLMQYIN-DTYRYLGDWr 291
gi 14520509 178 fpvPPQWVLHSKLANCEe----------yAKVFVYLMSQeg-------vKARIVRAPGEDHAWAEYYVEnYKIIFDPSNp 240
gi 18313054 177 --pNDRHLYVPPDLKPTl-----------EGIVANITAGc---------GDARCVAARIKAFLASGFIY-DGTLDAVWPe 233
gi 15606327   1 ------------------------------MNFFRIKRL----------LTMDRRDFLKGASALGLSFTlSSFSFSSR-- 38
gi 16802033 315 epqAAEVTYQTKQGDCKa-----------KTVLLKVILDy--------lEVDSELILVNYGSDVFLPVY-TPSPFNFNHa 374
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17227599 507 gLPYLSEQEDLVEAFlfk----ykGGYPDHFSTVLTVMLRSIGIPAR-------------LVAG---FSAGEFNPFTGMY 566
gi 11499934 186 -WANLIDFSRVVTVLp--------NGSVLDLTSNYTKTYNVTITIDQn------------VEKGi--LKVTTWKGSVERT 242
gi 11499976 192 -TSFMGTASYPDPEIr--------ALAEKITANATSDLEKVKAIESY-------------LKNN---YINTYVERTDVK- 245
gi 15895675 231 -VEDGNSNVIVYYNGvtldegirsNDQINNFARSLTSASKGNLNKAR-------------KLYD---WIGYDIDYDYQKA 293
gi 20093743 167 -SREYEIRNGQYWLP---------GEWCWITLNGTSLYGKVAKSPAQ-------------PFPN---AGEAERKLMNNNP 220
gi 15597240 292 aSERGYVPFSLAEIErn------gYGDCKDLAILLAAMLKAAGIKAEptlvsrgdvvwdlLVPG---MYAPNHAIVRAEV 362
gi 14520509 241 kNPVIVNPKQFGQLKnfsyveaydPANPDHKEDVSDEYIERGRLIVK-------------VVKGnepVSGATVEVLSTYL 307
gi 18313054 234 iPQGVDPVLWFLKEGk--------RGVCIHFASAFVLLARAAGVPAR-------------LVIG---YVSDGPVPTGw-- 287
gi 15606327  39 --KVTFSYDVDLPYK----------GEACPWLPVPINTDYQRVLDLR-------------FEGT---YRRAG-------- 82
gi 16802033 375 iLKVTDDNQVYFIDAtmssdqgflANRQRNSFMYYLEIKPGTELQKQ-------------EPFQ---DRTPSVEEIFRCD 438
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17227599 567 -----------------VVRNTDAYAMTEVYFPKY-----GWFTFDPIPNHPLIPPSVedvqtfs------------vlr 612
gi 11499934 243 vys------------kaVNKSDTVNLALATRIYKFelivpTWYFLEGYGAEVRHIGDSsse------------------- 291
gi 11499976 246 ------------------EFLFKTKRGTAREFAT------AFVLLAQSIGIPARAVFG---------------------- 279
gi 15895675 294 nm--------------vLNNNYNVKSGAIPTFNTR-----KGICFDYSCLYVAMARANni-------------------- 334
gi 20093743 221 m----------------FQAAVRLAYWVATHIPFIgw--fNWFPLAGYCGHLSPMYYEgpaa------------------ 264
gi 15597240 363 dgktwwldptnpvfapgRIMPDIQQRWALVLGADGkv-rrDEIPLEAPGDTLRVTRSEhythdgearvesrvelsnaplm 441
gi 14520509 308 re--------------rFPKRYDAPRYVVVNETGKdg--tTQFKLGPKEYKIMGKKCS---------------------- 349
gi 18313054 288 -----------------ALTAFSPHAWAEYYVEGv-----GWVGVEATPGGAAQAPLGavqlpl---------------d 330
gi 15606327  83 ------------------IYRDKVYGSPTLYA---------EFPRGESKKVLKLEVS----------------------- 112
gi 16802033 439 vkgnea-----evvferKLRGGMANGSREMFKNESnkdivNRYNFAIYSNMTLYKKYEeneid----------------k 497
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17227599 613 qfwqWVAGWLPTPVTGLFNTIFGTLFSWI-G-----------RAITWFITLFTQGWFGVLtgllvGTTTAF 671
gi 11499934 292 -yvkLKVNLYRETEYYFVFVGLLLGISICfLc----------YEVVLIYRKLKEDFGKTR----------- 340
gi 11499976 280 ----YLADPVETNQTIFASDAYVWAEVR--------------FKEGWMEFDPAPEGRGIntttaityidsk 332
gi 15895675 335 ---kVRLVTGEGFNGTSWVSHAWNQVYVPeM-----------GTWINVDTTFAKGGNYFNngsfnIDHRNS 391
gi 20093743 265 pllfPDEGWVCTDHAVLTVALYRAAGIPGyVg----------GELEPFGDHSWTAVRRR------------ 313
gi 15597240 442 qlsvADRQRGRTSTDQDLCRNFAKEGSDCvLerddsqfvlppSYTISARLTDRRALDRLGgeyfyNRQDLA 512
gi 14520509 350 ----FLICWKGESTGKVIAGSTTYAKLELr------------VDYVTTSILCALTIIPTGvlmlvIHKRYV 404
gi 18313054 331 appeTPAAAAPAGPPAPPLEIPSWILAAVaA-----------FVAIPIVLTARRRYITLGvgeefVVGGPA 390
gi 15606327 113 ------VEFSPRRVSLVD----------------------------------------------------- 124
gi 16802033 498 hfnnTSIQIVEDNKEMNEISLVYKATITDpY-----------IVENKKRFLHFWSWGNFIddgaeKHFHKD 557
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