731672 75 RIPHVVKLNSSKPKDELTSVQNKKLKTADGNNTpv---tkGVLLHESIHSVEDAYGKlp----edALAFLKENSAeiVPH 147 baker's yeast 20090911 1 -MYRTIRVPPEKGEEIREKAVAGNFLDPARKIRki---qtSTGTFLEIPVTEAAGEIvg------dFPVIKQEKPefLEK 70 Methanosarcina acet... 3025176 -------------------------------------------------------------------------------- Methanocaldococcus ... 20094376 1 -------------------------------------------------------------------MLSREEFA----R 9 Methanopyrus kandle... 15679211 -------------------------------------------------------------------------------- Methanothermobacter... 14521471 1 ------------------------------------------------------------------------MRTqvIKP 8 Pyrococcus abyssi 14590661 1 ------------------------------------------------------------------------MRTqgIKP 8 Pyrococcus horikoshii 1351597 6 VQKSEAKYWKDVVQNKNKFLKNIGIISGPKLVDtysnqfeADFLKKCVLIPTSYNKEdlpkdildCPRIYLIEEEvkSVQ 85 fission yeast 13541905 2 PTSLACVIEAPMANEIIRRLMIEDLIRKDLKIK-------KIENEIFIPVKDGTNLQq-------CRIVYSDFDE---RH 64 Thermoplasma volcanium 15791245 1 MRSLAVVVPKPDSQRAIDGLEDEGVYDDRRKVRe------HDADHVELPVTAEPDAVp-------FERAIAQADP---DP 64 Halobacterium sp. N...
731672 148 EYV---LDYDFWKAEEILRAVLPEqFleeVPTGFTITGHIAHLNLRTE-FKP-FDSLIGQVILDKNNKIECVVDKVSS-- 220 baker's yeast 20090911 71 TC-----SLKEYLSGTLTEAEMKH-I---PS-GWHILGDIIIVSIPET-LES-KKIQIAEALLSMYPKCRSVVRDFG--- 135 Methanosarcina acet... 3025176 1 -------------------------M---GI-KYQKIGDVVIV--KKE-LS---EDEIREIVKRTKC-KAILLYTTQ--- 41 Methanocaldococcus ... 20094376 10 R-------LEEELP-----DVADS-----VPHRWQELGDVVVIRLFDE-RAWaYRREVGRILREVTG-ARSVVALRR--- 67 Methanopyrus kandle... 15679211 1 ---------------------MKT-M---K---WARIGDIIVLN---------READDPEALLEMEG-VRSVIRVEG--- 39 Methanothermobacter... 14521471 9 R-------IREILSRELPPDLLAL-L---PK-RWVKLGDILLLPLRPE-LEP-YKYRIAEVYAKVLG-VKTVLRKGH--- 70 Pyrococcus abyssi 14590661 9 R-------IREILSKELPEELVKL-L---PK-RWVRIGDVLLLPLRPE-LEP-YKHRIAEVYAEVLG-VKTVLRKGH--- 70 Pyrococcus horikoshii 1351597 86 TDEklqIKVLRYVSQILHTTVSEEqYp--VPSRFVIYPPLALLSLNSFgTKEwHLFFQSYANVDVKAGLFDIFAREWNvs 163 fission yeast 13541905 65 Y-----ENIKQTMASFIKRNGGDErS---LPDKWIKLGDAIFVK--EL-ID----QTTFEAFERFMG-VRRAYLYES--- 125 Thermoplasma volcanium 15791245 65 RAP----DLGDRLRERGWSAAERE-R---APSSWAVLGSVILADFTDC-PRP---GEVGAALLELHREADTVLDRGDG-- 130 Halobacterium sp. N...
731672 221 ---------IATQFRTFP-MKVIAGKSDSLVVEQKESn---CTFKFDFSK-----------VYWNSRLHTEHERLVKQYF 276 baker's yeast 20090911 136 ---------IEGKFRQPK-RELLLGSG-AETIHKEHG----CFFKQDVTK-----------VMYSKGNLEERKRMSKLGQ 189 Methanosarcina acet... 3025176 42 ---------ITGEFRTPH-VKILYGKE-TETIHKEYG----CLFKLDVAK-----------IMWSQGNIEERKRMAFISN 95 Methanocaldococcus ... 20094376 68 ---------VSGTFREPV-GEVVAGDRNAETVHRELG----IRFKLDPTR-----------VMFARGNLEERRRLLESDL 122 Methanopyrus kandle... 15679211 40 ---------IHGPLRRPR-VRVLAGSG-TETVHKENG----CLFRIDLSR-----------VMWSRGNINERARIPSLVE 93 Methanothermobacter... 14521471 71 ---------IYGETRKPD-YEILYGND-TITVHVENG----IKYKLDVAK-----------IMFSPANVKERVRMAKVAK 124 Pyrococcus abyssi 14590661 71 ---------IHGETRKPD-YELLYGSD-TVTVHVENG----IKYKLDVAK-----------IMFSPANVKERVRMAKVAK 124 Pyrococcus horikoshii 1351597 164 hiainepipVGDVMRRPLsLKPLYGDFGVLIDGNPSEqdfqKAFWVSCRQngiyqtwaplyTMFSRGNSIEKARVLNFSY 243 fission yeast 13541905 126 ---------VRGVERIPV-VRHLYGLR-GEIRHVEDG----LTYFFDPEK-----------IMFSAGNTNERTRIREMKL 179 Thermoplasma volcanium 15791245 131 ---------VAGEHRTPD-VSVVAGDGDTETVHVEHG----TRYALDLAA-----------VMFSPGNKAERARMGDATG 185 Halobacterium sp. N...
731672 277 QpGQVVCDVFAGVGPFAVPAGKKDVI--VLANDLNPESYKYLKENIALNKVAKT-------VKSFNMDGADFIRQSpqll 347 baker's yeast 20090911 190 --GEIVVDMFAGIGYFSIPMAVHAHPekIISIEINPESFAYLNENIRLNQVEDI-------ITPIQGDCAEAAPE----- 255 Methanosarcina acet... 3025176 96 E-NEVVVDMFAGIGYFTIPLAKYSKPklVYAIEKNPTAYHYLCENIKLNKLNN--------VIPILADNRDVELK----- 161 Methanocaldococcus ... 20094376 123 E-GKLVFDMFAGIGYFTLPAALAGAE--VIAAELNPVACRYLVENARLNGVEGR-------VRVFLGDCREVARFV---- 188 Methanopyrus kandle... 15679211 94 E-GETVVDMFAGIGYFSIPVAVHSDPgrVYSVELNPDSFELLKSNITLNRVEGI-------IEPILGDCREVAPE----- 160 Methanothermobacter... 14521471 125 P-NELVVDMFAGIGHLSLPIAVYGKAr-VIAIEKDPYTFKFLLENIQLNKVQDR-------MSAYNMDNRDFPGE----- 190 Pyrococcus abyssi 14590661 125 P-DELVVDMFAGIGHLSLPIAVYGKAk-VIAIEKDPYTFKFLVENIHLNKVEDR-------MSAYNMDNRDFPGE----- 190 Pyrococcus horikoshii 1351597 244 IkDEIIADLYAGIGYFTFSYVKAGASt-VFCWEINPWSVEALRRAALKNGWSIYvvrngenYEFKVGTHRIVVFLEsnvy 322 fission yeast 13541905 180 D-GMTVLDMFAGIGYFTLPAVKYGHAehTDACDINPEAIKFLKKNLSANGISKS-------VKPICGDARIACPI----- 246 Thermoplasma volcanium 15791245 186 P-GERVLDMFAGVGYFALPMARAGAT--VTAVEKNPTAFRFLAENAQLNDVAET-------LDTILGDCREVDAP----- 250 Halobacterium sp. N...
731672 348 q---qwiqdEEGGKITIPLPLkkrhr-sqqhnDQQPPQPRTKELIIP--SHISHYVMNLPDSAISFLgNFRGIFAAHTKG 421 baker's yeast 20090911 256 ---------GEADRVIMGYVG-----------TTHHYLEPGIKALKKs-GGILHYHETVPENLFRTR-PEERIKKAARCL 313 Methanosarcina acet... 3025176 162 ---------DVADRVIMGYVH-----------KTHKFLDKTFEFLKD--RGVIHYHETVAEKIMYER-PIERLKFYAEKN 218 Methanocaldococcus ... 20094376 189 ---------RAADRVLMGYLK-----------GTLKFLPYACRAVRD--GGVLVVHEVFQKRWGEDR-VAREVLNALPDG 245 Methanopyrus kandle... 15679211 161 ---------LDADRVIMGYVG-----------RTHHFLDAAMECVRD--GGVIHYHETAPEAIRFSR-PLRRIERAA--H 215 Methanothermobacter... 14521471 191 ---------NIADRILMGYVV-----------KTAEFIPKALSIAKD--EAIIHYHNTVPEKLMPEE-PFATFKKIAREH 247 Pyrococcus abyssi 14590661 191 ---------NIADRILMGYVV-----------RTHEFIPKALSIAKD--GAIIHYHNTVPEKLMPRE-PFETFKRITKEY 247 Pyrococcus horikoshii 1351597 323 aaerfskmnISARHINLGMLP-----------SSEKSWSTATSILKResHSFIHVHENVKDEDIET--YSSEVNSCFSKM 389 fission yeast 13541905 247 ---------KAYDLIIMGNFK-----------S-IEYLPAALIRSKAg-TKIILHHLVSQERLS--K-FIYDLENYCISL 301 Thermoplasma volcanium 15791245 251 -----------ADRIVMGYYDalgggpvgdaaSTPGYLDAALDNLVS--GGVLHAHSAVPEAELWER-PLSRLRAGCQRA 316 Halobacterium sp. N...
731672 422 ATdtiQMPWVHVHCFEKYPPGdqvtedELHARVHARIIA 460 baker's yeast 20090911 314 GK---KVEVLAIRRIKKYSPG------VLHVVVDARIFE 343 Methanosarcina acetivorans C2A 3025176 219 GY---KLIDYEVRKIKKYAPG------VWHVVVDAKFER 248 Methanocaldococcus jannaschii 20094376 246 -F---EGEVLEVRRVKSFSPA------LDHYAVELRVRR 274 Methanopyrus kandleri AV19 15679211 216 PR---RVSLLDKRVIKKYSPG------VWHVVLDVRIH- 244 Methanothermobacter thermautotrophicus str. Delta H 14521471 248 GY---EAEKINELRIKRYAPG------VWHVVVDIKVFK 277 Pyrococcus abyssi 14590661 248 GY---DVEKLNELKIKRYAPG------VWHVVLDLRVFK 277 Pyrococcus horikoshii 1351597 390 LA---KNTVCVTNCVKSFSPR------VSHIVYDIETV- 418 fission yeast 13541905 302 GY---FTSIQEWHIVKSYSPK------MFHVATTLEILK 331 Thermoplasma volcanium 15791245 317 GRp--APTVLDTRRVKSHSEG------VFHVVIDARVP- 346 Halobacterium sp. NRC-1
Jiyao W et al.(2023). "The conserved domain database in 2023.",