16127643 8 GILVTLVTGIPVLLQLLKg-HPRGLIICFLAEMWERFSYYGMRAILIFYLTQHFL--------FDPKAASGHYGSYTALV 78 Caulobacter crescen... 15894038 4 RQTNDITINETLQNKKFKtkHPPGLYMLFFTEMWERFSYYGMRALLVLYLTTKFVqgg---lgVSDATATSLYGTFTSLV 80 Clostridium acetobu... 19553802 1 --------------------------------MWERFSFYGMQALLVYYLYFDVAagg---lgLDQTQATGLVGVYGALL 45 Corynebacterium glu... 19554244 17 PHLGSEVAETHREKKFFG--QPWGLANLFGVEMWERFSFYGMQSILAFYLYYSVTdgg---lgMNQTAALSIVGAYGGFV 91 Corynebacterium glu... 19074905 1 -------------MTIMN---GTTLFLIICNEFCERFCFYGLKSLLFSFTRSEYG--------FTIKESTVNLHFFISMS 56 Encephalitozoon cun... 19858877 1 -----MQNLNKTEKTFFG--QPRGLLTLFQTEFWERFSYYGMRAILVYYLYALTTadna-glgLPKAQAMAIVSIYGALV 72 Lactococcus lactis ... 15793245 1 ---MSRHPARTGEKTFFG--HPFQLSTLFHIELWERFSFYGMQGILLIYLYYTADkgg---lgIDKTLAGGIVGAYSGSV 72 Neisseria meningiti... 15677949 1 ---MSRHPAPTGEKTFFG--HPFQLSTLFHIELWERFSFYGMQGILLIYLYYTADkgg---lgIDKTLAGGIVGAYSGSV 72 Neisseria meningiti... 15926404 4 QNSHGNQIQDIPQTGFFG--HPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTdng---lgIDKTTAMSIMSVYGSLI 78 Staphylococcus aure... 19113209 63 YPSPTEEELATLPRVCGT--IPWKAFIIIIVELCERFAYYGLTVPFQNYMQFGPKdatpgalnLGESGADGLSNFFTFWC 140 fission yeast
16127643 79 YLVPLIGGFLADKWLGTRKAVAFGAVLLVAGHLAMAIEGkpavqtltyqgatyefqaegrgqnreaklvvdgkayevaat 158 Caulobacter crescen... 15894038 81 YLTPIAGGYISDRYLGQRKAITIGGIIMAIGQLTLFSSQs---------------------------------------- 120 Clostridium acetobu... 19553802 46 YLCCWAGGWVSDRVLGAEKTLLGGAISVTIGHLVLAGLG----------------------------------------- 84 Corynebacterium glu... 19554244 92 YMTSLVASFIADRVLGSERTLFYSAIIVMLGHIALALIP----------------------------------------- 130 Corynebacterium glu... 19074905 57 YLFTLFGGLLSDMFLGRYSTIVLLSSLYLTGTSLLTYCSi---------------------------------------- 96 Encephalitozoon cun... 19858877 73 YLSTIVGGWVADRLLGASRTIFLGGILITLGHIALATP------------------------------------------ 110 Lactococcus lactis ... 15793245 73 YLSTILGAWFADRVWGAEKTLFLSGIVVMLGHIVLAAA------------------------------------------ 110 Neisseria meningiti... 15677949 73 YLSTILGAWFADRVWGAEKTLFLSGIVVMLGHIVLAAA------------------------------------------ 110 Neisseria meningiti... 15926404 79 YMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLP------------------------------------------ 116 Staphylococcus aure... 19113209 141 YVTPVGAALIADQFLGRYNTIVCSAVIYFIGILILTCTAipsv------------------------------------- 183 fission yeast
16127643 159 kvgdfeikglpanaplpavlpkadykldVAGrdplyLNIFWFSLSLII-LGVGFLKP------NISTIVGQLYPQGDPR- 230 Caulobacter crescen... 15894038 121 ---------------------------mTAL-----YNGTFTSLVYLTpIAGGYISDrylgqrKAITIGGIIMAIGQLTl 168 Clostridium acetobu... 19553802 85 ------------------------------G-----KIGLAIGLGCIA-IGSGFVKT------AAITVLGSRHGEQEGDa 122 Corynebacterium glu... 19554244 131 ------------------------------G-----YTGLSIGLVLIG-LGSGGVKT------AAQVVLGQLYSRTDTR- 167 Corynebacterium glu... 19074905 97 ----------------------------VSG-----SPGLMVGSLLMIaVGTGGIKP------CVAAFGGDQFGPDDAQd 137 Encephalitozoon cun... 19858877 111 -----------------------------FG-----LSSLFVALFLII-LGTGMLKP------NISNMVGHLYSKDDSR- 148 Lactococcus lactis ... 15793245 111 -----------------------------PG-----LYGLLIGLIFIA-LGSGGVKS------TASSMVGALYEQDEMRp 149 Neisseria meningiti... 15677949 111 -----------------------------PG-----LYGLLIGLIFIA-LGSGGVKS------TASSMVGALYEQDEMRp 149 Neisseria meningiti... 15926404 117 -----------------------------FA-----LIGLFTSMFFII-IGSGLMKP------NISNIVGRLYPENDRR- 154 Staphylococcus aure... 19113209 184 -------------------------idaGKS-----MGGFVVSLIIIG-LGTGGIKS------NVSPLMAEQLPKIPPYv 226 fission yeast
16127643 231 -RDPGFTLYYYGIN---LG-SFWASILCGLLGVNVG------WWAGFGLAGVGMLAGFIVFVLGKPWLDGKAEPPEPKVL 299 Caulobacter crescen... 15894038 169 fSSQSMTALYIGLFlliIGnGFFKPNISTLVGHLYPdgd-krRDSAFTIFYMGINLGSFFAPLICGTLAETVMATTKAGQ 247 Clostridium acetobu... 19553802 123 kADPAFQLFYLGIN---VG-ALLGPLLTGWLSSRYS------FEMGFGAAAVLMIGGLGIYAALRKPMLQSFPLEVKKAL 192 Corynebacterium glu... 19554244 168 -RDAGFSIFYMGVN---LG-GLFGPLITNALWGWGG------FHWGFGIAAVGMALGLIQYVAMRKTTIGAAGHTVPNPL 236 Corynebacterium glu... 19074905 138 -LRRFFDFFYFAIN---IG-SMVSMVLTPTMSSVGClgkqscYPLAFGTSSTLLGASILLFIIGKRFYVIKPVRKEQFSR 212 Encephalitozoon cun... 19858877 149 -RDTGFNIFVVGIN---MG-SLIAPLIVGTVGQGVN------YHLGFSLAAIGMIFALFAYWYGRLRHFPEIGREPSNPM 217 Lactococcus lactis ... 15793245 150 lRDAGFSIFYIAIN---IG-GFLGPLLTGLLQENIG------FHYGFGAAAVGMAFGLWRYSLGR-KNLPHP--TVPHPL 216 Neisseria meningiti... 15677949 150 lRDAGFSIFYIAIN---IG-GFLGPLLTGLLQENIG------FHYGFGAAAVGMAFGLWRYSLGR-KNLPHP--TVPHPL 216 Neisseria meningiti... 15926404 155 -MDAGFVIFYMSVN---MG-ALLSPIILQHFVNVKN------FHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPL 223 Staphylococcus aure... 19113209 227 -KTKKNGSKVIVDP---VV-TTSRAYMIFYWSINVG------SLSVLATTSLESTKGFVYAYLLPLCVFVIPLIILAVSK 295 fission yeast
16127643 300 keKVAGPINRELAIYGLSLVGLv------gIFFLVQFNAIVGVALNIGILASLGYIG-FFMFTKCAkEERERLALAVFLI 372 Caulobacter crescen... 15894038 248 iiHYGFRYGFLVAGVGMIIGQI--------IFNSLSNKFLGDIGKVPVTKIKTGTNAeNKNRPLTR-QEKNRTIVICILA 318 Clostridium acetobu... 19553802 193 lrAQNPAEKHVISTAFAAVAVLcgvllyllLTETVSADQLAGALLLVTIGAALWLIIqPLRHPQVSsEEKRKVLAFIPIF 272 Corynebacterium glu... 19554244 237 --PKNEYARWIIGAVVVVAAVVal-----iATGIIKLEWLSNITAAIALIAAIALLAqMYVSPLTTaAEKSRLLGFIPMF 309 Corynebacterium glu... 19074905 213 --TFHSLVQNLKELFRRQSRDS----------ERKTQGTLKTVSEAACISHEE--------------DDKEKTLKILRIL 266 Encephalitozoon cun... 19858877 218 --DSKARRNFLITLTIVVIVAIigffllyqASPANFINNFINVLSIIGIVVPIIYFVmMFTSKKVEsDERRKLTAYIPLF 295 Lactococcus lactis ... 15793245 217 --SKGQGK-TAAAVGIALIAAlat----aiKTGLVNLDNFSGILLSTVILAVIVYFTrLLTNPRVSsDNKRHIIAYIPLF 289 Neisseria meningiti... 15677949 217 --SKGQGK-TAAAVGIALIAAlat----aiKTGLVNLDNFSGILLSTVILAVIAYFArLLTNPRVSsDNKRHIIAYIPLF 289 Neisseria meningiti... 15926404 224 --TPAEKKKYGLIIGSVVLAIVliiv-igaLTNSLSFNLVSNTVLVLGIALPIIYFTlIIRSKDVTdTERSRVKAFIPLF 300 Staphylococcus aure... 19113209 296 --RFYKHTPPSGSIFVRVGQV----------FFLAAQNKFNLEKTKPSCTTTVGRVTlKDQWDDLFiDELKRALRACKTF 363 fission yeast
16127643 373 FGAVVFWTLFEQAGSSLSLFAATNVQLDlvreplrlfsgavtlatpdqlakagidaasTFWvdTSFNAPQTQALNAGWIL 452 Caulobacter crescen... 15894038 319 AFVIIFWTGYEQAGSSFTLYTQNFLNRN-------------------------------VGs-FEVPVSWFQSLNPLFIL 366 Clostridium acetobu... 19553802 273 VCSTAFWAVQAQTYGVLAVYSQERVDRM-------------------------------VGd-FEIPAAWSQSLNPFFIL 320 Corynebacterium glu... 19554244 310 IGGVLFFAIFQTQFTVLAVYSDTRLDRN------------------------------FFG--IDLPPGLINSFNPIFII 357 Corynebacterium glu... 19074905 267 GPAAFFWMLSDQQSSSWVEQGTKMETHQs-----------------------------ILGygMDILPSQMQAFNAVFIL 317 Encephalitozoon cun... 19858877 296 LSAIVFWAIEEQSSTIIAVWGESRSNLDp----------------------------tWFGitFHIDPSWYQLLNPLFIV 347 Lactococcus lactis ... 15793245 290 LTICMFWAVWFQIYTVATVYFDETVNRTi-----------------------------GS---FTVPVAWKDSMQSLWVI 337 Neisseria meningiti... 15677949 290 LTICMFWAVWFQIYTVATVYFDETVNRTi-----------------------------GS---FTVPVAWKDSMQSLWVI 337 Neisseria meningiti... 15926404 301 ILGMVFWAIQEQGSNVLNIYGIEHSDMKl----------------------------nLFGwkTNFGEAIFQSINPLFIL 352 Staphylococcus aure... 19113209 364 LFYPIYWVCYGQMTNNLISQAGQMQTGN-------------------------------------VSNDLFQAFDSIALI 406 fission yeast
16127643 453 IFAPVFAAVWTFLGARG---KDPNPVIKFGLALIQVGAGFLLLQWGSTFADG-----------AFKLPLIFLVLMYMLHT 518 Caulobacter crescen... 15894038 367 ILGIPMSKLWLKLASSKn--GDLSIPTKMALGLILLGLGFLLMVGAVMQRGGnst------dtAIKASMLWMVGAYFFHT 438 Clostridium acetobu... 19553802 321 ALS-IPISLWFM--RGS---RAPRVKIGISIGVIIAGSGLLVLIPF---VG------------MPLAPVWVLPLSVFLIS 379 Corynebacterium glu... 19554244 358 IFSGIFATLWTK--LGA---KQWSTAVKFGVANIVIGCALFFFLPF--AGGa-----------ENSTPMALIIWVYFLFT 419 Corynebacterium glu... 19074905 318 LFIPLFSKMIYPLMGLAg--VFSSPEEKMGFGIALASLSFFCSGYLEYRIGLpa-------paGQRLSIMWQLPQYVLMT 388 Encephalitozoon cun... 19858877 348 LLSPIFVRLWNK--LGE---RQPSTIVKFGLGLMLTGISYLIMTLPGLLNGt-----------SGRASALWLVLMFAVQM 411 Lactococcus lactis ... 15793245 338 LFSGLMAAMWTK--MGR---KQPKTPLKFAMAVFVTGASFLGFVPF-ISAG------------TP-MPIAVFALIVLAIT 398 Neisseria meningiti... 15677949 338 LFSGLMAAMWTK--MGR---KQPKTPLKFAMAVFVTGASFLGFVPF-ISSG------------TP-MPIAVFALIVLAIT 398 Neisseria meningiti... 15926404 353 LLAPIISLLWQK--LGT---KQPSLPVKFAIGTFLAGASYILIGIVGYASG------------SSNFSVNWVILSYIICV 415 Staphylococcus aure... 19113209 407 IFIPICDNIIYPLLRKYnipFKPILRITLGFMFATASMIYAAVLQAKIYQRGpcyanftdtcvSNDISVWIQIPAYVLIA 486 fission yeast
16127643 519 TGELCMSPVGLSQMTKLSPASVVSFMMAVWFLAVAIAQWVGGKIAGLAATetvggqvLDPGAALAASLKVFNIIGLVAVA 598 Caulobacter crescen... 15894038 439 IGELCLSPVGLSMVSSLAPAKFASLLMGVWMLSNFVANKLAGIVAG--------------YTETLGHLQIFGGIAVIAIL 504 Clostridium acetobu... 19553802 380 LGELFIGPGGMAATAHHAPRIFATRFSALYFLTLAIGMSIAGNVSK-----------FYDPTNHTSELRYFAVFGISIIV 448 Corynebacterium glu... 19554244 420 IAELLLSPVGNSLATKVAPEAFQSRMFAVWLMAVSMGTSLSGTLGG-----------YYDPTDAGSEKVFFITVGVAAIV 488 Corynebacterium glu... 19074905 389 AGEIMLNVTGMEYMYTEAPEPMKSLVSSMWLLTVTAGNLLVMVLTFLDP--------VALFSSRAHDMWSFVAYGTAGLL 460 Encephalitozoon cun... 19858877 412 AGELLVSPVGLSVSTKLAPVAFQSQMMAMWFLADSTSQAINAQITP--------------LFKAATEVHFFAITGIIGII 477 Lactococcus lactis ... 15793245 399 IGELMISPIALSISTKIAPPLFKTQMVALNFLAFSLGFTLGGVLFEK-------------GYQAGDEIGFYRLLFYIGAA 465 Neisseria meningiti... 15677949 399 IGELMISPIALSISTKIAPPLFKTQMVALNFLAFSLGFTLGGVLFEK-------------GYQAGDEIGFYRLLFYIGAA 465 Neisseria meningiti... 15926404 416 IGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVK--------------LIEPLGQTNYFIFLGVVAII 481 Staphylococcus aure... 19113209 487 FSEIFASITGLEFAFTKAPPSMKSIITALFLFTNAFGAILSICISSTAVNpkltwmyTGIAVTAFIAGIMFWVCFHHYDA 566 fission yeast
16127643 599 IGIGFLLLSPVLKKWSHGAD 618 Caulobacter crescentus CB15 15894038 505 IGLVLLALNKKLEKMME--- 521 Clostridium acetobutylicum 19553802 449 IGVGSLMVAKKVG------- 461 Corynebacterium glutamicum ATCC 13032 19554244 489 LGAIVIAAKGWVLKKFIDVR 508 Corynebacterium glutamicum ATCC 13032 19074905 461 ASRCMFQASKAAKRNRK--- 477 Encephalitozoon cuniculi 19858877 478 VGIILLIVKKPILKLMGDVR 497 Lactococcus lactis subsp. lactis 15793245 466 TGFLLLLLVPKLNKMLEGTD 485 Neisseria meningitidis Z2491 15677949 466 TGFLLLLLVPKLNKMLEGTD 485 Neisseria meningitidis MC58 15926404 482 VTTIVLAFSPLIIKAMKGIR 501 Staphylococcus aureus subsp. aureus N315 19113209 567 MEDEQNQLEFKRNDALTKKD 586 fission yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",