Conserved Protein Domain Family
thiE

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PRK00043: thiE 
thiamine-phosphate pyrophosphorylase; Reviewed
Statistics
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PSSM-Id: 234590
View PSSM: PRK00043
Aligned: 311 rows
Threshold Bit Score: 151.874
Threshold Setting Gi: 153002954
Created: 9-Dec-2010
Updated: 17-Jan-2013
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
116671328   7 LTDARLYLCTDARTdrgdfadFVDAAYAGGVDIIQLRDKGLEAAEELELLEVLETAARRHGRLWSVNDRADIASLSGAPV 86 
119382795   1 MRLPRFYPIFDSSD-------WLRRALPLGVKLVQIRIKDQPPARLLGELALCQELCREHGAMLVVNDHWQAAIDLGCDF 73 
49475282    1 MKLDPFYPIVDNAD-------WVERLVPLGIKLIQLRMKNENLKTIREHIKRAKNICDKLGAQLIINDHWTIAIDEKCHF 73 
121602509   1 MKLDPFYLIVDNAD-------WIERCVPLGIKLVQLRIKNKDTELIRHHIKRAKNICDQFGAQFIVNDYWEIAIDEKCDF 73 
49474045    1 MKLDPFYLIVDNAD-------WVERLVPLGVKLIQLRMKNENPKIISQHIKRAKNICDKLGTQLIINDHWTIAIDEKCNF 73 
163867970   1 MKLDPFYLIVDNAD-------WVERLVPLGVKLIQLRMKDEDFQTISQHIKRAKNICDHWGAQLIINDHWRMAIDEKCHF 73 
110678113   1 MTLPRFYPIFDDVA-------WLRRMLPLGVKFVQLRIKDQPQDVLRAQLTEGRDLCRAHGALLVVNDHWQLAIDLGCDW 73 
56694976    1 MTLDRFYPIFDHTD-------WLRRMLPLGVKLVQLRIKDQSDPVIRAEIDTARDLCRAHGAVLVINDYWQAAIDAGCDW 73 
99078624    1 MTLDRFYPIFDDAN-------WLQRMLPLGVKLVQLRIKDQPIDVVQQQITRSRGLCRQHGAVLVVNDYWQLAIELGCDW 73 
294085540   1 MTLDRFYPIFDSCD-------WLRRMLPLGVKLVQLRIKDAPLDIVRREIVEAKALCDAHGAVLVVNDYWHIAIDAGCDW 73 
116671328  87 LHVGQKDLPLASARKFLGGEAVIGLSTHSHGQIDAAiaasrgAGGLDYFCVGPVWATPTKPGRAA----VGLELVRYAAE 162
119382795  74 IHLGQEDLDEADIPAIRKAGLRLGISTHDHAELDRAl-----ALRPDYVALGPVWPTILKKMKWEqqglDRVREWRRLVG 148
49475282   74 IHLGQEDLRNADLPAIRKNAIRFGLSTHDEHELDIAr-----SVDPDYIALGPIYPTILKEMKWMpqglEKIKQWRKQIG 148
121602509  74 IHLGQEDLNNADIPAIRKNGIKFGLSTHDEYELDIAl-----SFCPEYIALGPIYPTILKKMKWPpqglEKIKQWKKLIG 148
49474045   74 IHLGQEDLSNADLPAIRKNGIRFGLSTHDEHELDIAl-----SVHPNYIALGPIYPTILKEMKWMpqglEKIKKWKKRIG 148
163867970  74 IHLGQEDLRNADLHAIRKNNIRFGVSTHDEHELDIAl-----SVHPDYIALGPIYPTILKKMKWQpqglEKIKQWRKRIG 148
110678113  74 VHLGQEDLDAADVAAIRSAGLKLGISTHDKAELVRAl-----ALKPDYVALGPIYPTILKKMKWHqqgvEKLSEWKDRVG 148
56694976   74 LHLGQEDLDQADLPAIRKAGLRLGVSTHDDDELERVl-----GMDPDYVALGPVYPTILKQMKWHqqglPRVTEWKARVG 148
99078624   74 VHLGQEDLDDADLKAIRAAGLKLGVSTHDEDELDRVl-----ALSPEYVALGPVYPTILKHMKWHeqglPRVREWKTRIG 148
294085540  74 VHLGQEDMDNADLNAIRRAGIRLGFSTHDDDELERAl-----GFAPDYLALGPVYPTILKKMKWHqqglPRVTEWKARIG 148
116671328 163 aagkttakttggaagptvdgprLPWFAIGGIDLGNVEQVAAAGAERIVVVRAITEADDPAAAARSLLAALDAGA 236
119382795 149 a---------------------TPLVAIGGVTPERALEAFTAGADVASAVTDITLNPDPEGRIREWLRVAA--- 198
49475282  149 a---------------------LPLIGIGGLTPERAIGVLKAGANSAAVVTDILLHKKPEKRVRQWIKVTQAWR 201
121602509 149 p---------------------LPLVGIGGLTPERAINVLQVGANSAAAITDIILHKKPKERVQQWIKVTQKWR 201
49474045  149 a---------------------LPLIGIGGLTPERATDVLKAGANSAAVVTDIILHKKPRERVQQWIKVTKAWR 201
163867970 149 a---------------------LPFVGIGGLNPERAMDVLKAGTNSAAVVTDIILHKKPEERVKQWLKVTQPWR 201
110678113 149 d---------------------IPLVAIGGMSTDRAAAAFDAGADVVSAVTDIALHDDPESRVREWLEVCG--- 198
56694976  149 s---------------------IPLVGIGGMSVERAPGVLGAGADIVSVVTDITLNADPEARVHQWIEVTR--- 198
99078624  149 s---------------------IPLVGIGGMSVERAPGVFEAGADIVSVVTDITLNSDPEARVRQWVEATR--- 198
294085540 149 a---------------------IPLVGIGGMRVDRAAGVFESGADIISVVTDITLHDDPEARVKSWLEVTR--- 198
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