1B4R,1CTN,1EDQ


Conserved Protein Domain Family
PKD

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cd00146: PKD 
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polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Statistics
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PSSM-Id: 238084
View PSSM: cd00146
Aligned: 70 rows
Threshold Bit Score: 32.4686
Threshold Setting Gi: 2128879
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1B4R_A     1 XTLVgphgpLAs--gQLAAFHIAApl-----pvTATRWDFgdgsaevdAAg-pAASHRYvlpGRYHVTAVLAlga--gsA 70   human
1730587 1297 LRVEpa-acIPt--qPDARLTAYVtgn---pahYLFDWTFgdgssnttVRgcpTVTHNFtrsGTFPLALVLSsrv--nrA 1368 human
2627436 1262 LTAEss-spTElhsaTTVRAHLSSgn------nITWTFSMgdgk-sytLSe-pTVSHKYakdGRFTVNITAMna---vsS 1329 Takifugu rubripes
7305389 1209 LTVYls-psVEq--gAPMVVSASVesg----dnITWTFDMgdg--tvfTGpeaTVQHVYlraQNFTVTVEAAnp---agH 1276 house mouse
1730587 1468 VTSIkvngsLGlelqQPYLFSAVGrg-----rpASYLWDLgdg---gwLEg-pEVTHAYnstGDFTVRVAGWnev--srS 1536 human
1730587 1215 LSVDms-laVEq--gAPVVVSAAVqtg----dnITWTFDMgdg--tvlSGpeaTVEHVYlraQNCTVTVGAGspaghlaR 1285 human
3183107  229 EVAAgdggsFVrnrpVAFNVRLHDpshylrdadISYSWDFgdqsgtliSRs-pTVTHTYlqaGSFAARLVLQaaiplssC 307  chicken
2498795   66 QALDgrnkrFLrkqpLTFALQLHDpsgylagadLSYTWDFgdstgtliSRa-lTVTHTYlesGPVTAQVVLQaa----iP 140  cow
2498646  248 RNSSde-tfLKdl-pIMFDVLIHDpshflnystINYKWSFgdnt-glfVStnhTVNHTYvlnGTFSLNLTVKaaa-pgpC 323  human
6093865  249 ISDSifikdSPi--tFDVKIHDPSyyln--dsaISYKWNFgdgs-glfVEsgaTTSHTFslqGNFTLNLTVQai----iP 319  Japanese quail
1B4R_A    71 LL-GTDVQV 78   human
1730587 1369 HY-FTSICV 1376 human
2627436 1330 GWtIIPVEV 1338 Takifugu rubripes
7305389 1277 LSqSLHVQV 1285 house mouse
1730587 1537 EA-WLNVTV 1544 human
1730587 1286 SL-HVLVFV 1293 human
3183107  308 GT-SAPPVV 315  chicken
2498795  141 LTsCGSSPV 149  cow
2498646  324 PP-PPPPPR 331  human
6093865  320 VP-CKPVTP 327  Japanese quail
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