Conserved Protein Domain Family
KAZAL_SLC21

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cd01330: KAZAL_SLC21 
The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a member of the superfamily of kazal-like proteinase inhibitors and follistatin-like proteins.
Statistics
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PSSM-Id: 238650
View PSSM: cd01330
Aligned: 49 rows
Threshold Bit Score: 63.4773
Threshold Setting Gi: 47205277
Created: 16-Jun-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAC14919  500 LTAPCNAACSCQPEHYs-PVCGS-DGLMYFSLCHAGCpaatet-----nvdgqkVSGAAAYRPCPP 558 human
NP_499267 449 ISSTCNADCHCKMEWN--PVCDRnTGHMYYSACHAGCtgrt----------tidGSSQWSGCGCLT 502 nematode
NP_505689 508 VFDGCRDDCMCEQTPLy-PVCDV-SGSAYYSPCHAGCamgwknysifdntkatvDTLIFENCACVD 571 nematode
NP_509659 466 REQECLEYCNCETVLKf-DGVSY-NGQNFYSPCHAGCtey------------diYSNTWSNCQCAY 517 nematode
NP_508802 441 ALETCSENCHCDSFFN--PVCSEdSKLTFLSPCHAGCadmp---------gikfGASNWTNCGCSK 495 nematode
NP_609570 429 KQPYCSSQCLCTPTAFm-PVCPEnSSVTYFSPCYAGCtkkt----------tinSFQLFEGCSCSG 483 fruit fly
CAF94544  257 PAPSCISNCNCRTASAs-PVCGS-NAVTYLSACFAGC-----------------TRANLSGCWCVS 303 Tetraodon nigroviridis
CAG04193  309 PEAQCFSHCSCFNSTIs-PVCGS-NGLTYLSACFAGCtsr------------nsQAPTGSGCSCVS 360 Tetraodon nigroviridis
XP_413876 188 PYSPCNNNCECQTDSFt-PVCGA-DGVTYLSACFAGC-----------------SSTNLSGCSCLS 234 chicken
EAA43589  407 IKPFCASNCVCEENVPftPVCPIdSRFTYFSPCHAGCqdre----------einNIVIYRNCSCGV 462 Anopheles gambiae str. PEST
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