Conserved Protein Domain Family
RRM_MCM3A_like
?
cd12443: RRM_MCM3A_like (this model, PSSM-Id:240889 is obsolete and has been replaced by 409877)
RNA recognition motif in 80 kDa MCM3-associated protein (Map80) and similar proteins
This subfamily corresponds to the RRM of Map80, also termed germinal center-associated nuclear protein (GANP), involved in the nuclear localization pathway of MCM3, a protein necessary for the initiation of DNA replication and also involves in controls that ensure DNA replication is initiated once per cell cycle. Map80 contains one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain).
Links
?
Statistics
?
PSSM-Id: 240889
Aligned: 8 rows
Threshold Bit Score: 102.846
Created: 1-Jun-2012
Updated: 1-Feb-2013
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
O60318        435 TAIQCKNIPDyLNDRTILENHFGKIAKVQRIFTRrsKKLAVVHFFDHaSAALARKKGKsl---hkDMAIFWHRKK 506  human
XP_002413521  177 TTVLCNGLPAeLNDREALLEHFGQFGRVARITCNprKGCATVRFEDHqSAELAKKRGArisdrcaPLQIFWCSKR 251  black-legged tick
XP_002130399  277 NQLVCTGIPReSNDKDQLRRHFSRFGNVIRVQTNvnKNSASVKFSTNeEAAKAKMKGKnlf--gkAIHIYFGTKS 349  Ciona intestinalis
XP_002592293  424 TTLRCSDVPKmCNDKEFLRRHFSKFGKVVRVNPNrdKNTALISFADHkSASEAKKKGRllqkntrPITIFWGSGK 498  Florida lancelet
XP_001620418  262 KGLVIREIPEaFNKNPWLKRFYSRFGEVAKIICYprKKSASVIFKTHaAAEQAKRKGTvllpgtaPVSIFWKQDK 336  starlet sea anemone
AAT68037      482 TVIQSKNIPSiLNRKDLLMQHFGHFGKVLRVYSSlrKNLAIVHFQDHtSAAKAKKKGKlfq--rnEIQIFWQRKK 554  zebrafish
XP_002932075  776 TSIHVTNLPNhLNQKQYLEKFFKKAGKVQRMYCKpaRKIAVIHFNNHtAAANAKKMAKkl---hsDVCIFYYKKK 847  western clawed frog
XP_421891     252 TAIQCKNVPDyLNDRTVLEKHFGQFVKVRRVMTRrnKKTAVVHFFDHaSAALAKKKAKel---hkDIVTFWQKKK 323  chicken
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap