Conserved Protein Domain Family
RRM1_RBM19
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cd12564: RRM1_RBM19 (this model, PSSM-Id:241008 is obsolete and has been replaced by 409980)
RNA recognition motif 1 in RNA-binding protein 19 (RBM19) and similar proteins
This subgroup corresponds to the RRM1 of RBM19, also termed RNA-binding domain-1 (RBD-1), a nucleolar protein conserved in eukaryotes. It is involved in ribosome biogenesis by processing rRNA. In addition, it is essential for preimplantation development. RBM19 has a unique domain organization containing 6 conserved RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains).
Links
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Statistics
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PSSM-Id: 241008
Aligned: 12 rows
Threshold Bit Score: 120.876
Created: 19-Sep-2011
Updated: 1-Feb-2013
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9Y4C8         2 SRLIVKNLPngMKEERFRQLFAa-fGTLTDCSLKFTkdgkFRKFGFIGFKSEEEAQKAQKHFNkSFIDTSRITVEFC 77   human
AAH90711       2 SRLIVKNLPngMKEDRFRKMFAd-fGTLTDCALKFTkdgkFRKFGFVGFKTEEDAQKALKHFNkSFVDTSRVTVELC 77   zebrafish
NP_001034357   2 SRLIVKNLPngMKEDRFRKLFAa-fGTLTDCCLKFTkdgkFRKFGFIGYKSEDEAQAALNHFNrSFIDTSRVTVELC 77   chicken
NP_001088073   2 SRLIVKNLPngIKEDRFRELFAa-fGTLTDCSLKYTkdgkFRKFGFIGFVSEEEAKAALGHFNkSYIDTSRVSVELC 77   African clawed frog
EFX87687       2 TRIIVKNLPpsVSAQKLKETFSq-kGQVTDVQLKYDkdgkFRHFGFVGFKNDDEADSALSYFNnTFVGSCKIQVERC 77   common water flea
XP_002612017   2 SRLIVKNLPpsITEHKFQSMFEa-vGTVTDCKLKYSkngqFRHFGFVGFRSHQEAEKAVQQFHnSFLNTVRIQVEFC 77   Florida lancelet
AAM29657       2 SRIIVKQLPkhITEDKLRQIFGa-qGTITDLQLKYTpdgkFRQFCFVGYSTEEEAQSAIRHFDnTCIQTSRVRVESC 77   fruit fly
XP_002115714   2 SRLVVKNLPcnISEDRLRALFSe-fGELTDVQLKFTedkiFRRFAFIGYRHKCDASTAQKFFNnSYIDTSKIEIEPC 77   Trichoplax adhaerens
XP_002154579   2 SRLIVKNLPkdVKKESVKELFEsqgGEITDLKLCFTkegiFRKFAFVGYKTDTEALAALKFLNnTFMGTSKIHLEIC 78   green hydra
XP_002735981   2 SRIIVKNLPkgMKEEKFKNLFSe-rGEITDVQLKYTkdgiFRRFGFIGYKTATQAKSSMKHFNgTFIDTSKISVQIA 77   Saccoglossus kowa...
NP_502432      3 TRLIVKNLPstCTEQQLRKFFEk-yGQISDASLKYTkegkFRGFAFVGFLDEGSASNALAKSNqTFFNSKKLTVEEC 78   nematode
XP_002128145   2 SRLIVKNLPskINEEKLKKEFEp-yGTITDVKLMFSksgkFRRFAFVGYQFTENADKAKSKLDkSLILNQKISVETC 77   Ciona intestinalis
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