Conserved Protein Domain Family
rad18
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TIGR00599: rad18 
DNA repair protein rad18
All proteins in this family for which functions are known are involved in nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 273165
Aligned: 4 rows
Threshold Bit Score: 473.721
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P10862     1 MDH--QITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEF 78  Saccharomyces cerev...
CAA90033   1 MEPtfDIPDSTDWLDTPLTLLAPFETSLRCQVCKDFFDNPVITSCSHTFCSLCIRRCLSTEGKCPTCRSSDQELKLRRNW 80  Aspergillus nidulans
P33288     5 GDEafNVPDSTDWLGTPLACLMPVEQAFRCHVCKDFYDSPMLTSCNHTFCSLCIRRCLSVDSKCPLCRATDQESKLRGNW 84  Neurospora crassa O...
CAA21300   1 MNEl-DATDPSDWNQTKIPSLKGLDSSLRCLICHEYFRAPLITSCSHTFCSFCIRDYLREHPMCPACRAPEQESRLRKNT 79  fission yeast

P10862    79 LVSEIIQSYTSLRSSLLDALRIPKPTPVpENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDIL 158 Saccharomyces cerev...
CAA90033  81 VVQELVEGFKNARPSILQLARMAQTGTD-DSGDLAAEEPASKKRKIEPNAIVGTDGLPEEGIRTRSQSRGASRQPQATPV 159 Aspergillus nidulans
P33288    85 ALREAVEAFKNSRKVLLEFARTPPTIQA-ILPDQAGPSSPSKRKATEMEGPKEEDPESKRPRRSTRSTRARAAELTAAIL 163 Neurospora crassa O...
CAA21300  80 ILEEILESFKVIRPTLFEFLKVENVPK----PVLQAPET-----VIAQDSASG-DEEWEDDLAS-NSSPASIAKKTS--R 146 fission yeast

P10862   159 PLSSKpskRNFAMFRserikkksKpnEQMAQCPICQQFYPLKALEKTHLDeCLTLqslgkkpkISTTFPTESNpHNKSSS 238 Saccharomyces cerev...
CAA90033 160 QVIDD---GNDEDYM--------P--DGLVPCPVCGRRMKEEAVFRHLDS-CTGT--------AEELKPAAYR-SLAPGP 216 Aspergillus nidulans
P33288   164 QEEQDttpSADPDYVd------qPpdDGLVACPICLTRMKEQQVDRHLDTsCPGSpq-----aASKRRPIPAQ-TPQPST 231 Neurospora crassa O...
CAA21300 147 ----D----SKKRKR-----------EDLVHCPACSNLVPHNQINQHLDS-CLNSps----spSSSSSPYKNKdNSKSNS 202 fission yeast

P10862   239 RFKVrtpevdKSSCGetshvdkylnsmmsAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSN 318 Saccharomyces cerev...
CAA90033 217 RKSF------LAATG--------------KPPERLPVINYSLLKDTVLRKKLKDLGIPNWGPRALLQRRHTEWLNLWNAN 276 Aspergillus nidulans
P33288   232 FPSFnt--rlTSQTNq-------------KPPERLPALAYSMLRDTALRKKLSELGLSTHGSRQLLEKRHKEWITLWNAN 296 Neurospora crassa O...
CAA21300 203 LLSFkt--ddDSITKrrlrsfnsadelplKDRVRLPKLTYALLSESKIRSKLSEMGLPTDGHKQLLQRRHAKWVTLYNSN 280 fission yeast

P10862   319 fCDSLEPVDEAELKRQLLSWDVSHNktpqnsSNKggisklmiMKSNGKSSSYRKllenfknDKFNRKGWMVMFRKDFARL 398 Saccharomyces cerev...
CAA90033 277 -CDSRTPKPKRELLRELDVWERTQG------GNS--------VTPTDPTNAVMN-------KDFNTEEWSANYDTDFKAL 334 Aspergillus nidulans
P33288   297 -CDSSRPKKRSELLRDLDEWERTVGnpgtaaGGGggqqglglMARAQATGAQIKd------KEFDGKAWATRYGGSFGDL 369 Neurospora crassa O...
CAA21300 281 -LDQKQPVSKRNLIRQLIDWERVQS--------------------KS-IGVEKE--------KLGGGDWEKAYAEDFADL 330 fission yeast

P10862   399 IREAK---MKIKTGSSDsSGS 416 Saccharomyces cerevisiae S288c
CAA90033 335 IANARkknDAVIRSTIP-NAS 354 Aspergillus nidulans
P33288   370 IKQAR---QGIKRQTLDgNGE 387 Neurospora crassa OR74A
CAA21300 331 INRAK------Q-STTNkNDS 344 fission yeast
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