4HYT,3IXZ


Conserved Protein Domain Family
Na_K_ATPase_bet

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TIGR01107: Na_K_ATPase_bet 
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Sodium Potassium ATPase beta subunit
This model describes the Na+/K+ ATPase beta subunit in eukaryotes. Na+/K+ ATPase(also called Sodium-Potassium pump) is intimately associated with the plasma membrane. It couples the energy released by the hydrolysis of ATP to extrude 3 Na+ ions, with the concomitant uptake of 2K+ ions, against their ionic gradients. [Transport and binding proteins, Cations and iron carrying compounds]
Statistics
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PSSM-Id: 273446
Aligned: 21 rows
Threshold Bit Score: 453.357
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4HYT_B   1 MARGKAKE----EGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPG 76  pig
P14231   2 VIQKEKKScgqvVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFSLTMWVMLQTVSDHTPKYQDRLATPG 81  house mouse
P13638   2 VIQKEKKScgqvVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMWVMLQTVSDHTPKYQDRLATPG 81  Norway rat
P14415   2 VIQKEKKScgqvVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFPTAMFTLTMWVMLQTVSDHTPKYQDRLATPG 81  human
P54709   1 MTKNEKKSlnqsLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPG 80  human
Q60489   1 MTKSEKKSlnesLAQWKLFLYNPTTREFLGRTAKSWGLILLFYLVFYGFLAALFTFTMWAMLQTLNDEIPKYRDQIPSPG 80  domestic guinea pig
Q63377   1 MTKTEKKSfhqsLAEWKLFIYNPTSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWVMLQTLNDEVPKYRDQIPSPG 80  Norway rat
P97370   1 MTKTEKKSfhqsLAEWKLFIYNPSSGEFLGRTSKSWGLILLFYLVFYGFLAALFTFTMWAMLQTLNDEVPKYRDQIPSPG 80  house mouse
P18598   2 AALQEKKScsqrMAEFRQYCWNPDTGQMLGRTPARWVWISLYYAAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPG 81  Norway rat
P50992   2 AALQEKKScsqrMAEFRHYCWNPDTGQMLGRTPARWVWISLYYAGFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPG 81  house mouse
4HYT_B  77 LTQIPQS---QKTEISFRPNDPQSYESYVVSIVRFLEKYKDLAQKDDMIfEDCGNvPSELKERGEYNNERGERKVCRFRL 153 pig
P14231  82 LMIRPKT---ENLDVIVNISDTESWGQHVQKLNKFLEPYNDSIQAQKN--DVCRP-GRYYEQPDNGVLNYP-KRACQFNR 154 house mouse
P13638  82 LMIRPKT---ENLDVIVNISDTESWDQHVQKLNKFLEPYNDSIQAQKN--DVCRP-GRYYEQPDNGVLNYP-KRACQFNR 154 Norway rat
P14415  82 LMIRPKT---ENLDVIVNVSDTESWDQHVQKLNKFLEPYNDSMQAQKN--DVCRP-GRYYEQPDNGVLNYP-KLACQFNR 154 human
P54709  81 LMVFPKPv--TALEYTFSRSDPTSYAGYIEDLKKFLKPY--TLEEQKNL-TVCPD-GALFEQKGP---VY---VACQFPI 148 human
Q60489  81 LMVFPKPv--TALEYTFSVSDPSSYEGYIKDLKKFLKSY--SLDEQKNL-NKCTD-GVLFEQTGP---VY---AACQFPD 148 domestic guinea pig
Q63377  81 LMVFPKPp--TALDYTYSMSDPHTYKKFVEDLKNFLKPY--SVEEQKNL-TDCPG-GALFHQEGP---DY---SACQFPV 148 Norway rat
P97370  81 LMVFPKPq--TALEYTFSMSEPQTYKKLVEDLESFLKPY--SVEEQKNL-TSCPD-GAPFIQHGP---DY---RACQFPV 148 house mouse
P18598  82 VTLRPDVygeRGLQISYNISENSSWAGLTHTLHSFLAGYTPASQQDSIN---CSS--EKYFFQETFSAPNHTKFSCKFTA 156 Norway rat
P50992  82 VTLRPDVygeRGLKISYNVSENSSWAGLTHTLHSFLAGYTPASQQDSIN---CTS--EKYFFQESFAAPNHTKFSCKFTA 156 house mouse
4HYT_B 154 EWLGNCSGLNDE-TYGYKDGKPCVIIKLNRVLGFKPKPpknesletypvmkyNPYVLPVHCTGKRD----EDKEKVGTME 228 pig
P14231 155 TQLGDCSGIGDPtHYGYSTGQPCVFIKMNRVINFYAGA---------------NQSMNVTCVGKRD----EDAENLGHFV 215 house mouse
P13638 155 TQLGNCSGIGDPtHYGYSTGQPCVFIKMNRVINFYAGA---------------NQSMNVTCVGKKD----EDAENLGHFI 215 Norway rat
P14415 155 TQLGNCSGIGDStHYGYSTGQPCVFIKMNRVINFYAGA---------------NQSMNVTCAGKRD----EDAENLGNFV 215 human
P54709 149 SLLQACSGMNDP-DFGYSQGNPCILVKMNRIIGLKP-----------------EGVPRIDCVSK--------NEDIPNVA 202 human
Q60489 149 SLLEACSGTDDP-DFGYSQGQPCVLVKMNRIIGLKP-----------------EGSPRIDCISK--------DENTAMVS 202 domestic guinea pig
Q63377 149 SLLQECSGVNDS-NFGYSKGQPCVLVKMNRIIELVP-----------------DGAPYITCITK--------EENIANIV 202 Norway rat
P97370 149 SLLEECSGVTDA-NFGYSKGQPCILVKMNRIIDLIP-----------------DGYPQISCLPK--------EEN-ATIA 201 house mouse
P18598 157 DMLQNCSGLVDP-SFGFEEGKPCFIIKMNRIVKFLPS---------------NNTAPRVDCTFQDDpqkpRKDIEPLQVQ 220 Norway rat
P50992 157 DMLQNCSGLADP-SFGFEEGKPCFIIKMNRIVKFLPS---------------NNTAPRVDCTFQDDpqkpRKDTEPLQVE 220 house mouse
4HYT_B 229 YFGLGGypGFPLQYYPYYGKLLQPKYLQPLMAVQ--FTNLTMDTEIRIECKAYG-ENIGYS-EKDRFQGRFDVKIEVKS 303 pig
P14231 216 MFPANG--SIDLMYFPYYGKKFHVNYTQPLVAVK--FLNVTPNVEVNVECRINa-ANIATDdERDKFAGRVAFKLRINK 289 house mouse
P13638 216 MFPANG--NIDLMYFPYYGKKFHVNYTQPLVAVK--FLNVTPNVEVNVECRINa-ANIATDdERDKFAARVAFKLRINK 289 Norway rat
P14415 216 MFPANG--NIDLMYFPYYGKKFHVNYTQPLVAVK--FLNVTPNVEVNVECRINa-ANIATDdERDKFAGRVAFKLRINK 289 human
P54709 203 VYPHNG--MIDLKYFPYYGKKLHVGYLQPLVAVQvsFAPNNTGKEVTVECKIDGsANLKSQdDRDKFLGRVMFKITARA 279 human
Q60489 203 TYPNQG--VIDLKYFPYYGKKLHVGYLQPLVAVQvsFGSNSTKKEVTVECKIEGsKNLRNEdDRDKFLGRVAFKITARA 279 domestic guinea pig
Q63377 203 TYPDDG--LIDLKYFPYYGKKRHVGYRQPLVAVQviFGADATKKEVTIECQIDGtRNLKNKnERDKFLGRVSFKVIAHA 279 Norway rat
P97370 202 TYPEFG--VLDLKYFPYYGKKRHVGYRQPLVAVQvkFDSGLNKKEVTVECHIAGtRNLKNKnERDKFLGRVSFKVTARA 278 house mouse
P18598 221 YYPPNG--TFSLHYFPYYGKKAQPHYSNPLVAAK--FLNVPKNTQVLIVCKIMA-DHVTFDnPHDPYEGKVEFKLTIQK 294 Norway rat
P50992 221 YYPPNG--TFSLHYFPYYGKKAQPHYSNPLVAAK--LLNVPKNMQVSIVCKILA-DHVTFNnPHDPYEGKVEFKLTIQK 294 house mouse
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