Conserved Protein Domain Family
hnRNP-R-Q

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TIGR01648: hnRNP-R-Q 
heterogeneous nuclear ribonucleoprotein R, Q family
Sequences in this subfamily include the human heterogeneous nuclear ribonucleoproteins (hnRNP) R, Q, and APOBEC-1 complementation factor (aka APOBEC-1 stimulating protein). These proteins contain three RNA recognition domains (rrm: pfam00076) and a somewhat variable C-terminal domain.
Statistics
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PSSM-Id: 273732
Aligned: 3 rows
Threshold Bit Score: 627.798
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAH13481  11 NSDPTVGsstkvpEGVAGAPNEAALLALIERTGYTMVQENGQRKYGGPPPG--WEGPHPQRGCEVFVGKIPRDVYEDELV 88  house mouse
CAB94755   2 ESNHKSG------DGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELI 73  human
O43390   106 RQREKQGsk--vqESTKG-PDEAKIKALLERTGYTLDVTTGQRKYGGPPPDsvYSGVQPGIGTEVFVGKIPRDLYEDELV 182 human
AAH13481  89 PVFETVGRIYELRLMMD-FDGKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKRGEI 167 house mouse
CAB94755  74 PLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 152 human
O43390   183 PLFEKAGPIWDLRLMMDpLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNKTKENI 262 human
AAH13481 168 LEEIAKVTEGVLNVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMQTVKI 247 house mouse
CAB94755 153 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKI 232 human
O43390   263 LEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKV 342 human
AAH13481 248 LYVRNLMIETTEETIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRY 327 house mouse
CAB94755 233 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRY 312 human
O43390   343 LFVRNLATTVTEEILEKSFSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKK----- 415 human
AAH13481 328 QKAAKGGGGSAEAVAQ-QPSYVYSCDPYTLAYYGYPYNALIG--PNRDYFVKTGSIRGRGRGAAGN-R-TPGPRGSYL-- 400 house mouse
CAB94755 313 TRGTGGRGTMLQGEYTySLGQVYDPTTTYLGAPVFYAPQTYAaiPSLHFPATKGHLSNRAIIRAPSvRgAAGVRGLGG-- 390 human
O43390   416 -------RKERQAARQ---------ASRSTAYEDYYYHPP---------PRMPPPIRGRGRGGG---R---GGYGYPPdy 464 human
AAH13481 401 GGYSAGRGIYSR--YHEGKGKQQEKGYELVPNLEISPVNPVAIKP-GTVAIPAIGAQYSMfQAAPAP------KIIEDGK 471 house mouse
CAB94755 391 RGYLAYTGLGRG--YQVKGDKREDKLYDILPGMELTPMNPVTLKPqGIKLAPQILEEICQkNNWGQPvyqlhsAIGQDQR 468 human
O43390   465 YGYEDYYDDYYGydYHDYRGGYEDPYYGYDDG------YAVRGRGgGRGGRGAPPPPRGR--GAPPP----------RGR 526 human
AAH13481 472 IHTMEHMISPIAVQPDPATaAAAAAAAAAAAVIPAVSTPPPFQGRPITpVYTVAPNvQRIPTAGIYGASYVPFAAP-ATA 550 house mouse
CAB94755 469 QLFLYKITIPALASQNPAI-HPFTPPKLSAFVDEAKTYAAEYTLQTLG-IPTDGGD-GTMATAAAAATAFPGYAVPnATA 545 human
O43390   527 ----------AGYSQRGAP---LGPPRGS---RGGRGGPAQ-QQRGRG-SRGSRGN--RGGNVGGKRKA-DGYNQPdSKR 585 human
AAH13481 551 TIAtLQKN-AAAAV-------YGGYAGYIPQAFPAA-LQVPIHDVYQ-TY 590 house mouse
CAB94755 546 PVS-AAQLkQAVTL-------GQDLAAYTTYEVYPTfAVTARGDGYG-TF 586 human
O43390   586 RQTnNQQNwGSQPIaqqplqqGGDYSGNYG---YNN----DNQEFYQdTY 628 human
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