Conserved Protein Domain Family
cysJ

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TIGR01931: cysJ 
sulfite reductase [NADPH] flavoprotein, alpha-component
This model describes an NADPH-dependent sulfite reductase flavoprotein subunit. Most members of this family are found in Cys biosynthesis gene clusters. The closest homologs below the trusted cutoff are designated as subunits nitrate reductase.
Statistics
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PSSM-Id: 273882
Aligned: 8 rows
Threshold Bit Score: 926.409
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P38038         8 SALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWG--VLNQQP-AALAATPAPAAEMPG----------ITIISASQTGN 74  Escherichia col...
Q8K9D3         8 NIFFPLSLDKIENLEKIKKNCSSIQYAWLSGYFWN--LANQTP-SRLICEKNEFFRKDNee------kiITIISASQTGN 78  Buchnera aphidi...
P57503         8 DPVFPLSSEQLNNLKELERTCTNIQSAWLSGYFWK--IANQTS-NITSFQTNESEKNDp---------vITIISASQTGN 75  Buchnera aphidi...
WP_011073521   8 SLASPLSQSQVDKLKQLTAELNSVQLAWVSGYLAA--TANTSG-SAIQVAASVTEAQAAq--------tVTILYGSQTGN 76  Shewanella onei...
WP_010980903   7 QNTNPPLPPLPPEITQLLSGLDAAQWAWLSGYAWA--KAGNGA-SAGLPALQTALPAAEpf-------sVTVLSASQTGN 76  Neisseria menin...
WP_011066054   5 ETNSPFNKEQSDYLNKLLPTLTESQRIWLSGYLSAkqLADSDTkAQQSTNPILAHEQSLkpvnetklrdVTILYGSETGN 84  Oceanobacillus ...
WP_011052199   8 LPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAG--LAQGHPpRSLAVLPGGQAHPLAqeg-----qrLTVVYGSQTGN 80  Xanthomonas
WP_014906544   8 VMNSPFNQEQAELLNRLLPTLTESQKIWLSGYLSAq-SVSAQEaAGTPAAAVSAEAPAPavs-----keVTVLYGSQTGN 81  Bacillus subtilis
P38038        75 ARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLG 154 Escherichia col...
Q8K9D3        79 ARQLAKRFNKYLKNENKKTNLIDAADYNFKKIKNERFLILIISTQGEGEPPEEALSFYKFIMSKKAPRLENLHYSVFGLG 158 Buchnera aphidi...
P57503        76 AKLLSKRLYEYFNKNNKISRLIDAMDYKFKKIKDEKILILIISTQGEGEPPEEALSFYKFIMSKNAPNLNNLYYSVFGLG 155 Buchnera aphidi...
WP_011073521  77 GRGIAKALAEKAKTQGYSVNLASMGEYNVRQLKQETLLLLVVSTHGEGEAPDDAIELHKFLATKRAPQLNNLHYSVLALG 156 Shewanella onei...
WP_010980903  77 AKSVADKAADSLEAAGIQVSRAELKDYKAKNIAGERRLLLVTSTQGEGEPPKEAVVLHKLLNGKKAPKLDKLQFAVLGLG 156 Neisseria menin...
WP_011066054  85 GETIAKDLGEKVESRDFKVTISSMDNFKAKDLKKVQDIFIITATHGEGDPPENAISFHEFLHGRKAPKLKDVRFSVLSLG 164 Oceanobacillus ...
WP_011052199  81 ARREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYVVISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLG 160 Xanthomonas
WP_014906544  82 AQGLAENAGKQLEQSGFQVTVSSMSDFKPNQLKKVTNLLIVVSTHGEGEPPDNALSFHEFLHGRRAPKLEDLRFSVLALG 161 Bacillus subtilis
P38038       155 DSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKsraPVA--APSQSVAtGAVNEIH--TSP 230 Escherichia col...
Q8K9D3       159 DVSYNLFCQAGKDFDKRFSELGGKSLLHRLDSDIEYESNYIQWSEELLLAIN---KIDvsTCSVFKKnDKKNFID--KLN 233 Buchnera aphidi...
P57503       156 DTSYNLFCQAGKDFDKRFKELGGNSLLDRFDADIEYEDNYNKWSQDLLQSINskeKIYksSVSYIDQ-ENTLILS--KNH 232 Buchnera aphidi...
WP_011073521 157 DSSYEFFCQTGKDFDARLSALGAKALLPLVECDVDYEAAAGQWHADVLTAVKpliQTTanVVALNEInSTSAQVAs-ESE 235 Shewanella onei...
WP_010980903 157 DSSYPNFCQAGKDFDRRFEELGAKRLLERVDADLDFTASANAWTDNIAALLKeeaAKNraTPAPQTTpPAGLQTAp-DGR 235 Neisseria menin...
WP_011066054 165 DQSYEFFCQTGKEFDNRLEELGGDRLYPRVDCDVDFDDLAAEWIDGVLHELSk--AKSahDPELSET-STEIDTE--GPV 239 Oceanobacillus ...
WP_011052199 161 DSSYADFCGIARRIDERLAELGGSRVQPRGEADLDIDSVALPWRAQALTHAReqlKGG--LHSAT---VTPLRSSpaTPV 235 Xanthomonas
WP_014906544 162 DSSYEFFCQTGKEFDQRLEELGGKRISPRVDCDLDYDEPAAEWLEGVLKGLNe--AGGgsAAPAP---AAASQTG--ESS 234 Bacillus subtilis
P38038       231 YSKDAPLVASLSVNQKITGRNSE-----------KDVRHIEIDLGDSGMRYQPGDALGVWYQNDPALVKELVELLWLKGD 299 Escherichia col...
Q8K9D3       234 YTKYKPAVATVLLNQKITGRNST-----------KDVHHIELDITNSNIVYTPGDALGVWYQNSSQLIKQILKLLSIRIS 302 Buchnera aphidi...
P57503       233 YTKKNPAEGIILTNQKITGRNSK-----------KDVHHIEIDISNLNIKYSPGDALGVWYKNDSNLVKNILELLSINIS 301 Buchnera aphidi...
WP_011073521 236 FTKQNPYRAEVLVSQKITGRDSD-----------RDVRHVEIDLGESGLHYEVGDALGVWFSNSEILVGEILAGLGLAAD 304 Shewanella onei...
WP_010980903 236 YCKAAPFPAALLANQKITARQSD-----------KDVRHIEIDLSGSDLHYLPGDALGVWFDNDPALVREILDLLGIDPA 304 Neisseria menin...
WP_011066054 240 YSRTNPFHAEVLENLNLNGEGSN-----------KETYHMELSIEDANFEFEIGDSLGIYPKNNPDMVEQLITGLNFEPE 308 Oceanobacillus ...
WP_011052199 236 WSHQQPFAAELLSNQIISGRDFKgpgfrvyaapgKRVRHLEFSLQGSGLSYEPGDALGIRHRNPPALVDAVLQTLRLDGD 315 Xanthomonas
WP_014906544 235 YSRTNPFRAEVLENLNLNGRGSN-----------KETRHVELSLEGSGLTYEPGDSLGVYPENDPELVELLLKEMNWDPE 303 Bacillus subtilis
P38038       300 EPVTVE--GKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVG--DKAKLQHYAATTPIVDMVR--FSP--AQL 371 Escherichia col...
Q8K9D3       303 DKVKVK--DKIITIFEALKKNFELTTNTKHIIQKYTDVTQNKFLKKIIS--DNKKLNNYVKKTPLLKMIY--DHP--KKL 374 Buchnera aphidi...
P57503       302 ETITIK--NDVITIFDALQNHFELTNNTKNIIKSYANFSKNKFLKDIIS--NDSDLENYTINTPLIKMIH--DHP--LKL 373 Buchnera aphidi...
WP_011073521 305 AKVTVG--SESISLKQALIDKKELTQLYPGLVKAWAELSASSELLALSE--DKEQLRQFILNHQFVDLVTnyKLPaeANL 380 Shewanella onei...
WP_010980903 305 TEIQAG--GKMMPVARALSSHFELTQNTPAFVKGYAAFAHYEELDKIIA--DNAVLQDFVQNTPIVDVLH--RFP--ASL 376 Neisseria menin...
WP_011066054 309 GSVSINkqGERRSLREALLTNFEISRITKPLLEKAAQYFNNNNLKDLVTpeKVEEQKAYIQGRDVIDLIT--DYPp-VDM 385 Oceanobacillus ...
WP_011052199 316 AAVTIG--EQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQALLAptQTAGLASLLADHQVIDVLR--RWP--ADW 389 Xanthomonas
WP_014906544 304 EIVTLNkqGDVRPLKEALISHYEITVLTKPLLEQAAQLTGNDELRELLApgNEENVKAYIEGRDLLDLVR--DYGp-FSV 380 Bacillus subtilis
P38038       372 DAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANP 451 Escherichia col...
Q8K9D3       375 SSQQLISILRPLKPRLYSISSSQSEMNDEVHITVGVVKKQISGTIHLGGSSSYLSQFLKIDDSVKIFVEEKSNFRLPENK 454 Buchnera aphidi...
P57503       374 SSQQLIGLLRPLTPRLYSISSSQEEIDNEIHITVGVVKKLISGHVYLGGASGYLSQSLKSDDIIKIFIQTNDNFRLPINK 453 Buchnera aphidi...
WP_011073521 381 DANKLLELLRPLTPRLYSIASSQTEVDTEVHLTVALVEDEHQGQTRFGGASHFLAS-AQEGAEVKVYVEPNKHFRLPENP 459 Shewanella onei...
WP_010980903 377 TAEQFIRLLRPLAPRLYSISSAQAEVGDEVHLTVGVVRFEHEGRARTGGASGFLADRLEEDGTVRVFVERNDGFRLPEDS 456 Neisseria menin...
WP_011066054 386 TPEEFIQILRKMPARLYSISSSFRANPDEVHITVAKAIYTGNRQEQAGVCSGQCAERVTPGDLLPIYIHRNPNFKFPNDV 465 Oceanobacillus ...
WP_011052199 390 DHAGLLAALRPLTPRLYSVASSRKRVGDEVHLTVDEVTYQAHGHAHLGAASGFLAA-LGEGDTAPVYIEPNERFRVPADA 468 Xanthomonas
WP_014906544 381 SAQEFVSILRKMPARLYSIASSLSANPDEVHLTIGAVRYDAHGRERKGVCSILCAERLQPGDTLPVYVQHNQNFKLPKDP 460 Bacillus subtilis
P38038       452 ETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDK 531 Escherichia col...
Q8K9D3       455 DVPIIMIGSGTGIAPFRAFIQQRDNDKATGKNWIFFGNPNFTEDFLYQLEWQKYLKKKLLTKMSLAWSRDQKEKIYVQDK 534 Buchnera aphidi...
P57503       454 NTPIIMISSGTGIAPFRAFMQQRDNDNADGKNWLFFGNPNFTEDFLYQVEWQKYIKKGLITNMNLAWSQDQKNKIYVQDR 533 Buchnera aphidi...
WP_011073521 460 DTPVIMIGPGTGVAPFRAFMQERVAQGAKGDSWLFFGNPHFEQDFLYQTEWQQYLKNGDLTRIDVAFSRDQAHKIYVQHR 539 Shewanella onei...
WP_010980903 457 RKPIVMIGSGTGVAPFRAFVQQRAAENAEGKNWLIFGNPHFARDFLYQTEWQQFAKDGFLHRYDFAWSRDQEEKIYVQDK 536 Neisseria menin...
WP_011066054 466 DTPVIMIGPGTGVAPYRSLLEEREEIGANGRTWLFYGDQHFATDFLYQVEWQNWLKKGVLTKMDVAFSRDSADKVYVQHR 545 Oceanobacillus ...
WP_011052199 469 DRDILMIGPGTGVAPFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQAEKLYVQHR 548 Xanthomonas
WP_014906544 461 ETPIIMVGPGTGVAPFRSFMQEREETGAEGKAWMFFGDQHFVTDFLYQTEWQNWLKDGVLTKMDVAFSRDTEEKVYVQHR 540 Bacillus subtilis
P38038       532 LREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY 599 Escherichia coli K-12
Q8K9D3       535 IRENGKELWEWVNQGAQIYVCGNASKMAKDVEKELLDVFSKNGSMDIEESSEFLNNLRITRRYQRDVY 602 Buchnera aphidicola str. Sg...
P57503       534 IRENSQEIWSWIEEGAQIYVCGNASKMAKDVEKALLDIISHNAHLNLEESQEFLNNLRLNKRYKRDVY 601 Buchnera aphidicola str. AP...
WP_011073521 540 IKEQGQALWQWLQNGAHLYICGDAERMAKDVHQALLAVAVEFGGLSSEAAEEYFETLRSHKRYQKDVY 607 Shewanella oneidensis
WP_010980903 537 IREQAEGLWQWLQEGAHIYVCGDAAKMAKDVEAALLDVIIGAGHLDEEGAEEYLDMLREEKRYQRDVY 604 Neisseria meningitidis
WP_011066054 546 MLEHSKELFQWLQDGANIYVCGDEKYMANDVHQMLSTIIQKEGRYSFEEAEAYLTDMRKQKRYQRDVY 613 Oceanobacillus iheyensis
WP_011052199 549 LRARGAEVYAWLQGGAHVYVCG-ATSMGKDVHAALLDIVATHGAQDAEAAAAYLTQLQVEGRYARDVY 615 Xanthomonas
WP_014906544 541 MLEHSAELFEWLQEGAAVYICGDEKHMAHDVHNTLLEIIEKEGNMSREEAEAYLADMQQQKRYQRDVY 608 Bacillus subtilis
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