Conserved Protein Domain Family
LRR_2
?
sd00032: LRR_2 
leucine rich repeats
A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.
Links
?
Statistics
?
PSSM-Id: 275379
Aligned: 65 rows
Threshold Bit Score: 110.418
Created: 8-May-2013
Updated: 22-Oct-2014
Structure
?
Aligned Rows:
Download Cn3D
  next features
Feature 1:leucine-rich repeat [structural motif]
Evidence:
  • None
Scroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1     ###########           #####                                                     
Q8W0T3    206 IQALFLTDISIkph-----ldmRGFTKLRRLLLDLVHItgd--lpgLLSNCCSLEDLELIACSGvt---dLNIPHRLDKL 275 sorghum
Q8GVM0    156 LRVVELRTCHFpngm----apaLHFPRLARLTLYRVTIsedt-lhgLLSRCSALESLLLVGNFGir--rlRINSPFLRSL 228 Oryza sativa Japon...
Q8GVM3    159 LVVLYLSSCGFpdem----pptLHFPRLKQLTLCSVAIseda-ihgVLSRCPALESLLLQGNFGvr--rlRINSASLRSF 231 Oryza sativa Japon...
Q8GVU6    192 LEVVSFSSCCFrddm---inqpLHFPKLRKLNLHSVATseda-lhaVISACPTLESLHVNYTIGlr---rLHRSASLRSI 264 Oryza sativa Japon...
Q9LYZ4    132 VKQLFVDSGSVhlip----rctVSWTSLKNLSLSNCTLsdes-flkILSGSPLLESLELLYCAEymc-ldLSQSQHLRRL 205 thale cress
Q8LQV2    195 MVRLAVARCGLppy------tdVDLPRLRELVLCEGHFraanklgrMLAGCPKLESLTLINPNDmpysamEVVSSTMKIL 268 Oryza sativa Japon...
Q84W80    162 LKQLYLDFGCKkdfislnpkcsVSWTSLKNLSLYHCNIsdes-iaiILSGCPILESLLLFFCKKlkv-ldLSKSPRLITL 239 thale cress
Q9LYZ2    150 LKRVELRYVDLmpr------cmVSWTSLKNLSLTDCTMsdes-fleILSGCPILESLSLKFCMSlky-lnLSKSLRLTRL 221 thale cress
Q7XWQ4    164 LRRLLLTNWTLdvp-----aggVSMPSLETLFLKRIMAedga-vqrLISGCPNIADLTLEQCPSvk--rlVVASPRLDSF 235 Oryza sativa Japon...
Q9LSJ3    148 LKQLDVTLDFFdmip----tcaVSWKSLRNLTLRFCQIpdes-mhnILSGCPILESLTLDTCRLler-ldLSKSPNLRRL 221 thale cress

Feature 1                                                                                     
Q8W0T3    276 RHllish-------------mdiqmVDFHVTGLAHFEYKGGVIpiqlh-----gcskLEKATITFKQDNKtlgha----- 332 sorghum
Q8GVM0    229 GFsasswegy-------rdanfqevVIEDAPCLERLMPLYPNHgpati----rviaaPKLEVLGVLSDGIsqlhlgttff 297 Oryza sativa Japon...
Q8GVM3    232 GFyskswgfssaswngfagaelqevVIEDAPCLERLLPLCPNDgvaai----rviaaPKLEIMGPLSDGIsqlhlgttif 307 Oryza sativa Japon...
Q8GVU6    265 CVgtthglnq--------evvfqevVVEDAPLLERLMPTLLDDgppsi----rvisaPRLHILGILPSFIsrleigtvv- 331 Oryza sativa Japon...
Q9LYZ4    206 EIdrsdw--------------fmgpTKIVAPHLHCLRLRHSRLpcslv-----dvssLTEADLNIYFGDLktvtagflq- 265 thale cress
Q8LQV2    269 VLcifh---------------tkvlDLLDAPSLERLIIWRPMLvmslymfmikitraPILRAIGYLDTILhvvqiggtii 333 Oryza sativa Japon...
Q84W80    240 EItrrc---------------rmepTQLVAPHIRCLRLINSEKpcalv-----dvssLSQAELDITAYAIvdnkleadfh 299 thale cress
Q9LYZ2    222 EIerisyi-----------rapmlsMQIVAPYIHYLRLRDSEAhctfv-----dvssLTEANVDVSTFHPrtcyhdfdpl 285 thale cress
Q7XWQ4    236 AMicch---------------hashVVLQAERLRTLRYKGGLPge----------nfFSIANCGDVLAMTidicesllgk 290 Oryza sativa Japon...
Q9LSJ3    222 DInrqyr--------------rtgpIAIVAPHIYYLRLTYSSTpstiv-----dvssLSEANLNIISDRLlspltadry- 281 thale cress

Feature 1                                                                                     
Q8W0T3    333 ---------ftaipSISEVKVLNMHADMEayhpvwvsqghmvttrptYMFANLRHLTCEIkiftrgpne-------hsgl 396 sorghum
Q8GVM0    298 ----qkmiavnlttSIRTVKVLVLDSNGPnldvv---------vdflKCFPCLERLYVVSrphkvikn--------irsy 356 Oryza sativa Japon...
Q8GVM3    308 ----qemtavslttSMRSVKVLVLDSDGPnldav---------vdflSCFPCLERLYIASqpfkvikn--------trry 366 Oryza sativa Japon...
Q8GVU6    332 -----iqemppvsvSVPTVKILVLQSVGPnlaav---------vnilKYFPCLEKLYIKI-------------------- 377 Oryza sativa Japon...
Q9LYZ4    266 ------hnvvkmlqMLQNVEKLTIGGTFLqmlsl--------aalcgVPFPTLKVKTLTLetmiirs-----------vi 320 thale cress
Q8LQV2    334 ----eagtkispslTIPSVETLAIKLSFGskeqen------rllsflKIFPNVKTLYVMShppctsscvfhderdvdfwm 403 Oryza sativa Japon...
Q84W80    300 -----qtmvvkmleKCQNVEKLTLGANFLkmlsl--------aelrgVSFPKLKAKALILetmisry-----------vi 355 thale cress
Q9LYZ2    286 dphdllvmvqtmlkTFQKVEKLTLGVNLLqmlsl--------skipsLPLPMLKVKTLTLetmiirs-----------vv 346 thale cress
Q7XWQ4    291 sa-savvpitkvitRCTNVTFLHLHLRPTmafhsg------tftralRHLPHLRQLALKGlldnde------------ta 351 Oryza sativa Japon...
Q9LSJ3    282 -----qtmalemlsKFHNVKRLTVGETILqilsl--------aelrgVPFPTLKVQTLTVktefvrs-----------vi 337 thale cress

Feature 1                 
Q8W0T3    397 lqlaHYLSFAPQ 408 sorghum
Q8GVM0    357 dplhPIECMELH 368 Oryza sativa Japonica Group
Q8GVM3    367 dplnPIECIQFH 378 Oryza sativa Japonica Group
Q8GVU6    378 ----TLQSTAKN 385 Oryza sativa Japonica Group
Q9LYZ4    321 pgitKLLRYTPG 332 thale cress
Q8LQV2    404 knlgSILCVHSQ 415 Oryza sativa Japonica Group
Q84W80    356 hgivKVLQNSPD 367 thale cress
Q9LYZ2    347 pgiaRLLQNLPG 358 thale cress
Q7XWQ4    352 lsvsTLLRNTPN 363 Oryza sativa Japonica Group
Q9LSJ3    338 pgisRLLQNSPG 349 thale cress

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap