3VSC,1Z7Y,3DWG


Conserved Protein Domain Family
PALP

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pfam00291: PALP (this model, PSSM-Id:278708 is obsolete and has been replaced by 395228)
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Pyridoxal-phosphate dependent enzyme
Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Statistics
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PSSM-Id: 278708
View PSSM: pfam00291
Aligned: 148 rows
Threshold Bit Score: 75.0341
Threshold Setting Gi: 8928478
Created: 10-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3VSC_B        90 FFERGKPTPL-----VRSRLQlpn---gvrVWLKLEWYN-PfSLSVADRPAV---EIISRLSRRv----eKGSLVADATS 153 Aeropyrum perni...
Q9ZMX5        74 KRYENFDNPK-----NPAPIFaln----erLFVQELYHG-P-SLAFKDMALQplaSLFSNLAVGk----nEKYLVLVSTS 138 Helicobacter py...
Q8Q0K3        60 lTTEAGPITYksealAKELGLsnlyigfsgYWPEREALI-K-TCSFKELEAH---PTMQLLKES------GGKAIVLASA 128 Methanosarcina ...
Q2CJ64        21 IDLGQGGTPL-----VKSRRIgaea-gipdLRFKLEQLN-P-TGSYKDRFAG---LAVGLARAE------GHAACVATSS 83  Oceanicola gran...
ABX03866      68 APTHVGGTPL-----LHAQRFggll-glprLYIKDERYS-P-TNSFKDRQAA---LAVAALVSN------DIRECVIAST 130 Herpetosiphon a...
WP_003153970  82 VFAHDAVAPL-----RQLNGNe---------WV-LELFHgP-TLAFKDFALQ----LLGRLLDHvlakrgERVVIMGATS 141 Pseudomonas aer...
WP_010951920  82 GFRHRGIAPLqql--------------ghnEWILQLFHG-P-TRSSKDFAAQ----LQARFVRHflgaecERVMLVGASN 141 Pseudomonas putida
WP_011822196  66 VSFSEGYTPLrrv--------------kdrVLLKLENRN-P-TGSYADRASSlvaSFIASTRNH------PSMVTIPYTE 123 Hyperthermus bu...
WP_012185424  56 ISLGEGFTRI-----RRING----------VVIKYEGNN-P-TGTYYDRGSA---VLASVSNNGd---------VELTFE 106 Caldivirga maqu...
WP_011838489  60 ISLGEGWTPL-----IRSDNLfrn----enIYFKDESRN-P-TGSFRDRAAA---LIVSDALDQ------GAKRLVVASD 119 Staphylothermus...
3VSC_B       154 SNFGVALSAVAR--LY-GY-RARVY--LPGAAEE--FGKLLPRLLGA---QVIVD------------PEAPSTVhlLPRV 210 Aeropyrum perni...
Q9ZMX5       139 GDTGPATLEGLA-----GMpNVFVVclYPKDGT---SLVQKLQMVTQnasNLKVFgvs-------gdFDDAQNA--LKNL 201 Helicobacter py...
Q8Q0K3       129 GNTGRAFAYSSS--LT-GT-DAYIV--VPDSGV---SSIWLPEEPAN---SIHLIsmtp-----gndYTDAINL--AGRL 189 Methanosarcina ...
Q2CJ64        84 GNTGAALAAFCA--RA-GM-GCALY--VSENAPQ--GKLEQMLAYGA---DVYRVarftidaaesgrISETLER----EA 148 Oceanicola gran...
ABX03866     131 GNAAVAYASACA--AV-GI-KLWVF--MTSVVPE--AKLREAALFGA---EVIKVsg---------nYDQTKQI--AADF 188 Herpetosiphon a...
WP_003153970 142 GDTGSAAIEGCR--RCdNV-DIFIM--HPYNRVSevQRRQMTTILGD---NIHNIaie-------gnFDDCQEM--VKAS 204 Pseudomonas aer...
WP_010951920 142 GDTAVAAIEALRhcPAaG--LLALY--PSAGTPA--DRAAVMRSAASdsvSCVAVdg---------sFDDCQSL--VSAL 204 Pseudomonas putida
WP_011822196 124 -DYTVSLSLYLR-----GItGVRVVa-DPRTVNP--SDVIILDRLGV---DIVFS-----------------------SD 168 Hyperthermus bu...
WP_012185424 107 EDLTRSLALYLS--MV-GA-KVTVS--VDSNVDP--RDLLILAKLST---RVCVN-----------------------CV 152 Caldivirga maqu...
WP_011838489 120 GNMGASIAAYSA--KA-GL-PVTIY--VPVWTDP--EKILLMKAYGA---KVIVSee---------dLDTLLQY--VERR 177 Staphylothermus...
3VSC_B       211 MKDsknEGFVHVNQFy--NDANFEAhMRGTAREI----FvqsRRGG----LALRg--VAGSLGTS-GHMSAAAFYLQS-- 275 Aeropyrum perni...
Q9ZMX5       202 LKDddfNEALKARQLk--LSVANSVnFGRIAFQIvyhiWgflELYKkgaiNSKEk--ITLAIPSG-NFGNALGAFYAK-- 274 Helicobacter py...
Q8Q0K3       190 AKL---PGMVPEGGAr--NVARREG-MGTVMLDA----A---VTIG----KMPDh--YFQAVGSGtGGMSAWEASLRLrd 250 Methanosarcina ...
Q2CJ64       149 AAR---GMQLFITAYa-vSPGPMEG-IKTLAYEI----A---EDAP----EVAD---IFLPVGGG-GLFVATGRGFDDlv 208 Oceanicola gran...
ABX03866     189 AQN---RNIIYDRGAn--SIPAREA-MKTISYEI----C---EQLGw---QAPDw--YIQAVSGG-LGPLGVYHGFAElh 249 Herpetosiphon a...
WP_003153970 205 FAD---QGFLKGTRLvavNSINWARiMAQIVYYFha-----aLQLG----APHRsvaFSVPTGNF-GDIFAGYLARNM-- 269 Pseudomonas aer...
WP_010951920 205 LRDw--PCPGLIPVSf--NSTNWVGvLAQIVFYFh----------------------AALQLGGG-IRPVGFSIPTASfa 257 Pseudomonas putida
WP_011822196 169 ATN---LNNTSLLDYl--SPLTIEG-LKTIAYEI--------VEAR----PNSSr--VIVPSETG-LLALAIAKGFYE-- 225 Hyperthermus bu...
WP_012185424 153 KNP--------SVDYf--DPLLIEG-FKTISYEL----I---EQLN----DLRA---VTVPVERG-ALALALVKGFME-- 204 Caldivirga maqu...
WP_011838489 178 ARK---EKLYNASSTy--NILAMEG-LKTIGYEI----Y---LQYG----GVPSt--VYVPLGSG-LTILSLYHGFSEmh 237 Staphylothermus...
3VSC_B       276 --VDPS--------IRAVLVQPA--QGDSIPGIRr-------------------------------vETGMLWINM---L 309 Aeropyrum perni...
Q9ZMX5       275 --KMGL---------NIAKIKVVtnSNDVLREFIetgrydltk----------------rslkqtfsPAMDILKSS---N 324 Helicobacter py...
Q8Q0K3       251 dgRFGSk------lPKLQLAQNL--PFVPMYNAWkagrreiipdidmkdakkqieetyatvltnrapPYSITGGLYdalV 322 Methanosarcina ...
Q2CJ64       209 saGERAr------pPRLHAVQPV--GNDTVATPLregaakarpvdta--------ttisglgvgyilDGDEVVARA---R 269 Oceanicola gran...
ABX03866     250 amGLTQr------vPQTAIIQAE--GCSPMVQAFqagksvaekvvpn-------triailstgdpgkIYTRLWQRI---Q 311 Herpetosiphon a...
WP_003153970 270 --GLPV---------SQLIVATN--RNDILHRFMsgnrydkdtlhps--------lspsmdimvssnFERLLFDLH---G 325 Pseudomonas aer...
WP_010951920 258 eiYAGFiaqkmglpINQIIVSTN--RNDALHRFIhcnrysrgstsqt--------lspvmdfslfsnLERFVWELY---D 324 Pseudomonas putida
WP_011822196 226 --------------ANMAGIDAS-------YEVVaaaveg----------------------sgepeLARYAPIKVkv-- 260 Hyperthermus bu...
WP_012185424 205 --LEDK------------GIISN------MPKIIgvh---------------------------vgpLKSPIGDQL---R 234 Caldivirga maqu...
WP_011838489 238 snNIIDh------iPKLIGVETC---ANPVYSSIhgnptkcneep------------mpglyyrkpvLKEYVSEII---D 293 Staphylothermus...
3VSC_B       310 DISYtlaeVTLEEAMEAVVEVArSDGLVIGPSGGAAVKALakkaaeGDLEPG-DYVVVVPD 369 Aeropyrum pernix K1
Q9ZMX5       325 VERAlfslFGFERTLELMQALEeEKFYALKP---KELALLqehfscASCSDE-DCLKTIQE 381 Helicobacter pylori J99
Q8Q0K3       323 DTDGimyaITREEALEAKALFEsLEGIDILEPSAVAAASLlkaveaGNVEKDdVILLNIAG 383 Methanosarcina mazei Go1
Q2CJ64       270 ASGGrgyvIDEDRVRAVQRRLAqEEGLLVEPAGAVAVAGAldaaarGELAGDgPVVCVLTG 330 Oceanicola granulosus HTCC2516
ABX03866     312 TSGGtmeaVTDEEAFSAMRLLArTEGISVEPATAVAFAGLqkmvaqGQVNPEeLIVVNCTG 372 Herpetosiphon aurantiacus DSM 785
WP_003153970 326 RNGKa--vAELLDAFKASGRLSvEDERWTEArkl---------fdsLAVSDE-QTCETIAE 374 Pseudomonas aeruginosa
WP_010951920 325 RDGGa--tRALMEHFEACGELSiGNRQWL--HARMLFDSYav--ddALIREE-----IVTl 374 Pseudomonas putida
WP_011822196 261 ------eyVSSEEVVKALVELS-RRGLRVKPLSAAAYAAA------LNLGEG---VAVITS 305 Hyperthermus butylicus
WP_012185424 235 ELGIkfmgVKPEDTINAVVELA-KHSVFARPISASAYVAA------KEIHES---VAVVSG 285 Caldivirga maquilingensis
WP_011838489 294 KHGEti-vVNNKQVYMAAKKLAmEEGLFVEPSSAVALAGA------LKIGGTeNSIILLTG 347 Staphylothermus marinus
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