pfam00629: MAM (this model, PSSM-Id:279023 is obsolete and has been replaced by 459878)
MAM domain, meprin/A5/mu
An extracellular domain found in many receptors. The MAM domain along with the associated Ig domain in type IIB receptor protein tyrosine phosphatases forms a structural unit (termed MIg) with a seamless interdomain interface. It plays a major role in homodimerization of the phosphatase ectoprotein and in cell adhesion. MAM is a beta-sandwich consisting of two five-stranded antiparallel beta-sheets rotated away from each other by approx 25 degrees, and plays a similar role in meprin metalloproteinases.
Jiyao W et al.(2023). "The conserved domain database in 2023.",