2P0R,2ARY


Conserved Protein Domain Family
Peptidase_C2

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pfam00648: Peptidase_C2 (this model, PSSM-Id:279042 is obsolete and has been replaced by 395523)
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Calpain family cysteine protease
Statistics
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PSSM-Id: 279042
View PSSM: pfam00648
Aligned: 176 rows
Threshold Bit Score: 290.131
Threshold Setting Gi: 829176923
Created: 15-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2P0R_A         36 FEDADFPASNSSLF----Y-----------S--ERPQ---IP-----F-VWKRPGEIV----------K--------N-- 69   human
XP_002299263 1668 FTDQEFPPNDQSLY----M-----------D--PRNP---PSklqvvS-EWMRPVEIV----------Kesh--ldsH-- 1712 black cottonwood
FAA00210       76 FVDDQFPPTENALY----Fp---------sS--SSRP---NK-----C-QWLRPQQITfssndtdwrnR--------E-- 121  vase tunicate
XP_001774206 1717 FTDQEFPPSDQSLFvdtdH-----------P--AAKL---QV-----VnKWSRPEEVL----------R--------Eqg 1757 Physcomitrell...
XP_002990425 1631 FTDQEFPPTNQSLF----I-----------N--PEQP---LPklqvvQ-QWVRPAELV----------R--------Dig 1671 Selaginella m...
EKC20180      502 FVDDSFPPAPTSVF----L-----------N--ENKPftkSY-----I-QWLRPTEIA----------AprhgdekvK-- 546  Pacific oyster
ERG80174      215 FIDDSFPQCLKSIG----DlsrnneqrmkpKvkANE-----------L-IWLRPQDMFtkdg---hryT----------- 264  pig roundworm
CDP98362      143 FIDDSFPHSKKSIG----Nfiide-rlngkKidANH-----------F-IWLRPQDIYtkdg---rryR----------- 191  Brugia malayi
EGT57661       87 FIDDQFLHNKKSIG----TlhftkngvkrhEe-PDF-----------L-HWLRPSQMFtkdg---rsfP----------- 135  Caenorhabditi...
NP_001256151   35 FIDDSFLHNKKSIG----SlqftkngvkrhEe-PDF-----------L-NWLRPSQMFtkdg---rssP----------- 83   Caenorhabditi...
2P0R_A         70 ----PE-FILGGATRTDICQGEL-GDCWLLAAIASLTLNQKALARVIPQDqsfGPgYA--GIFHFQFWQHSEWLDVVIDD 141  human
XP_002299263 1713 ----PC-LFSGAANPSDVCQGHL-GDCWFLSAVAVLTEVSRI-SEVIITP---EYnEE--GIYTVRFCIQGDWVPVVVDD 1780 black cottonwood
FAA00210      122 ----WS-VFS-NPSPTDIKQGVL-GNCWFLSALAVLAERPDLLKRVMVTK---NYnKE--GVYVVRLCKAGVWQTVFVDD 189  vase tunicate
XP_001774206 1758 qdsrPC-LFAGTANPSDVCQGHL-GDCWFLSAVAVLTEASRI-SDVMITP---EFnEE--GIYTVRFCIQGEWVPVVVDD 1829 Physcomitrell...
XP_002990425 1672 tnarPR-LFEGFTKPADVCQGRL-GDCWFLSAVAVLTAASRI-SEVIITP---EYnEE--GIYTVRFCIQGEWVPVVVDD 1743 Selaginella m...
EKC20180      547 ----WA--VCRTPLPDDISQGLL-GNCWFLSALAVLAERPELVESIILTKd-----YCpqGAYQVRLCKDGKWQIVLIDD 614  Pacific oyster
ERG80174      265 ----WTvFrd--pKASDIEQGSL-GNCWFLSSLAVIAERPDILEQIVLTK---VYnpF--GIYQIRLCVDGRWQVVVVDD 332  pig roundworm
CDP98362      192 ----WSvFld--pKPSDIEQGCL-GNCWFLSALAVIAERPDILDQIFLTK---TYnpW--GVYQIRLCVDGHWQVILVDD 259  Brugia malayi
EGT57661      136 ----WSvLnn--pRPSDIEQGTLvGDCWLMSAMALIAERTDVLDEIIPRK---QYshY--GVYQIKLCVEGKWKVVIVDD 204  Caenorhabditi...
NP_001256151   84 ----WSvLnn--pRPSDIEQGTLvGDCWLMSAMALIAERPDVLDDIIPKK---QYshY--GVYQIKLCVEGKWEVIIVDD 152  Caenorhabditi...
2P0R_A        142 RLPT----F-RDR-LVF--LHSADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAMEDFTGGVAETFQTK------E--- 204  human
XP_002299263 1781 WIPCe---S-PGK-PAF--ATSQKGNELWVSILEKAYAKLHGSYEALEGGLVQDALVDLTGGAGEEIDMR------S--- 1844 black cottonwood
FAA00210      190 LLPC----D-EKRrLIY--SH-ARGKQLWVPLVEKALAKLHGCYEALQAGRSIEGLATLTGYPCESLALQ------Q--- 252  vase tunicate
XP_001774206 1830 WIPC----EaRGK-PAF--ATSRKGNELWVSILEKAYAKLHGSYEALEGGQVHDALVDLTGGAGEEIDLT------Neva 1896 Physcomitrell...
XP_002990425 1744 WIPCe---F-KGK-PAF--ATSRKRHELWVSVLEKAYAKLHGSYEALEGGHVQDALVDLTGGAGEEIDLT------S--- 1807 Selaginella m...
EKC20180      615 LLPCd---H-HKR-LVF--SQ-AKRKQLWVPLIEKAMAKLHGSYESLVAGKCLEGLATLTGAPCDNIELQpgpqkeE--- 683  Pacific oyster
ERG80174      333 FFPChartR-----GLAfaVGRRN--QLWVPLIEKAFAKISGSYAKLLAGRTVEGLAVLTGAPCSQLDlenvs------- 398  pig roundworm
CDP98362      260 FLPChsqtH-----GLAfaVGRRN--QLWVPLIEKALAKVLGCYAKLPAGRTLEGLAILTGAPCTFLDlenc-------- 324  Brugia malayi
EGT57661      205 FFPCynhtN-----SIAmaVGRRN--QLWVPLIEKAMAKELGSYSRLHGASLTQGLSMLTGASCLTMH------------ 265  Caenorhabditi...
NP_001256151  153 FFPCysktN-----SIAmaVGRRN--QLWVPLIEKAMAKVLGSYSKLHGASLAQGLSMLTGASCVNYNcppip------s 219  Caenorhabditi...
2P0R_A        205 ----APE-------N-------F-YEILE-----KALKRGSLLGC-F-IDTRSaAESEAR-TPFGLIKGHAYSVTGID-Q 256  human
XP_002299263 1845 ----AQAqidlasgR-------L-WSQLL-----RFKQEGFLLGA---GSPSG-SDVQ-V-SSSGIVQGHAYSLLQVR-E 1900 black cottonwood
FAA00210      253 ----SCP-------EteveedmV-WVKLL-----SSMEAGYLMGA-ScGGGNMdTNDEEY-NQIGLRPRHAYSVLRVTsE 313  vase tunicate
XP_001774206 1897 qldlASG-------H-------L-WSQLQ-----RFKQEGFLLGA---GSPSG-SDVH-V-SSSGIVQNHAYSLLQVR-E 1949 Physcomitrell...
XP_002990425 1808 ----AQAqldlasgR-------L-WSQLL-----RFKQEGFLLGA-G-SP--S-GSDAHV-SASGIVQGHAYSLLQVR-E 1863 Selaginella m...
EKC20180      684 ----IDP-------N-------LiWAKLL-----SCRESRFLMGA-ScGGGNM-KTEDKVyEEKGLRPRHAYSILDVK-D 737  Pacific oyster
ERG80174      399 spdsEQM---------------L-WASLLs----MREA-RFIMGCsC-GAgkryvdd-akykavGLQPRHAYSLLDVA-E 454  pig roundworm
CDP98362      325 --tdhdL---------------I-WAQLLs----MREA-GFIMGCsC-GSgrryvne-aefrrvGLQIRHAYSLLDVK-E 378  Brugia malayi
EGT57661      266 ----VLR---------------F-REVLMmltlfGHKS-GFLMCChC-GSfensvae-aeframGLLTNHAYSILDVR-Y 321  Caenorhabditi...
NP_001256151  220 svddVDT---------------F-WAQLVs----SKES-GFLMCChC-GAfenvvae-aefkamGLLTNHAYSILDVI-Y 275  Caenorhabditi...
2P0R_A        257 VSFRGqRIELIRIRNPWG-QvEWNGSWSDSSPEWRSVGPAEQKRL--CHT-ALD-DGEFWMAFKDFKAHFDKVEICN 328  human
XP_002299263 1901 VD----GHKLVQIRNPWAnEvEWNGPWSDSSPEW---TDRMKHKL--KHV-PQSkDGIFWMSWQDFQIHFRSIYICR 1967 black cottonwood
FAA00210      314 YNIKF-IFRLVQLRNPWG-HfSWKGDWSNESVLWQQ-NPQLANQL--FQR-NAD-NGTFWMCLEDMMKYFDSVDICK 383  vase tunicate
XP_001774206 1950 VD----GHKLVQIRNPWAnEvEWNGPWSDFSPEW---TDRMKHKL--KYSpQAA-NGVFWMSWQDFQLHFRSLYVCR 2016 Physcomitrella p...
XP_002990425 1864 VD----GHKLVQICNPWAnEvEWNGPWSDSSLEW---TDRMKHKL--KYSpQAQ-DGVFWMSWQDFQLHFRSVYVCR 1930 Selaginella moel...
EKC20180      738 IDGN----RLLRLRNPWG-RfSWNGDWSDDSARWANISTRAKQDL--MLY-GHT-SGVFWMALDDVLKYFDSVDICK 805  Pacific oyster
ERG80174      455 Yn----gHRLVRLRNPWG-TfVWNQDWSDSWSGW---TTRARAVLlpN-G-P-E-AGTFWMPFTQFLKHFDTVDVAK 519  pig roundworm
CDP98362      379 Yn----nQRVVRLRNPWG-SfTWNGPWCDTWSGW---DETSRRILlpD-G-P-E-AGAFWMPFLDFMQRFDSVEVAK 443  Brugia malayi
EGT57661      322 En----gNRLLRIRNPWG-QfVWNGKWSDGWPGW---PAEMKQRLlyGRR-D-E-TGAFWMDLDDFIHRFASVTVCK 387  Caenorhabditis b...
NP_001256151  276 Eq----gYRLLRIRNPWG-QfVWNGKWSDGWPGW---PIGMKQKFlnQRK-D-E-TGAFWMDLEDFVARFASVTVCK 341  Caenorhabditis e...
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