Conserved Protein Domain Family
CD36
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pfam01130: CD36 (this model, PSSM-Id:279474 is obsolete and has been replaced by 460076)
CD36 family
The CD36 family is thought to be a novel class of scavenger receptors. There is also evidence suggesting a possible role in signal transduction. CD36 is involved in cell adhesion.
Links
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Statistics
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PSSM-Id: 279474
Aligned: 229 rows
Threshold Bit Score: 267.103
Created: 21-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6DHC7         17 GALIALLGGI-LIP----VGDMIIkntVHK----ETVLE-NGTLAFDTWTSVDi-AMYRQFWIFNVENPDKVLSEGSKPV 85   zebrafish
XP_004348174   28 GALLLAVGIA-IDPa---VNW-LVkmeVKDs---VMLTS-TSSALYDQWQNPSi-PIYMTFFMFNVENPEEVFDHGSPPF 97   Capsaspora ow...
GAA56005       16 AALFIVIALFtLILv---LIFDRLflaLLAq---KLAIS-PNSPVYESWLVPTv-PIYFSVYLLNLTNPTEVLA-GARPH 86   Clonorchis si...
XP_003388574   47 mITTAIIAAV-LAVl---ISYGIIdkeVDKfiakQVSLT-KGSAATDQWSKPGa-AVYMSFYMFNLTNKDEFLN-GEKAT 119  Amphimedon qu...
XP_003387595   14 sgctvvslillslaialiieFPSLldhMVNe---KLTIL-PGHSSYEQLKDPSl-PVYKDVYFFNLTNPVEFSQ-GARPI 87   Amphimedon qu...
CDJ01379       19 ltlsclvllttlglvtceLLFDTIesnLLVk---ELIIT-ENSSSFQV-LTTNs-NNAVQFFFFNLTNAKEWQKNRKKPR 92   Echinococcus ...
XP_001747074  141 GVLCLVIGLV-VNPv---I--DSLmvkTIKe---NVELKsENSQLYPIWSNTTkvPTYMTFYMYNLTNPEDVLQGG-KPR 210  Monosiga brev...
CDS27098        2 vFFMLTAFSS-LVIl---LLFESIvdvKISe---SIKLY-NGSAAFKRWKAKSs-PSKFTVYLYNLTNSNQVLA-GERPN 71   Hymenolepis m...
CDJ01817       45 ilsCLVASIA-LSLmtceLLFDTIegtIIGk---KLVIT-ENSSSFQI-LTTDf-SSTLQFYLFNLTNAEEWQRNGTKPR 117  Echinococcus ...
XP_011405711   52 GTLLVAGLGV-VYYy-----KNQIffyIFNk---ELSLT-KSSPMTPIWLKQPp-EIY-NIYYFNITNPDEIQYEGAAPN 119  Amphimedon qu...

Q6DHC7         86 LVQKGPYTYRvRYIPKTNITFN-----D----NN---T--VSFVLPAGATFE----------PSMSV--GS--E-E-DVF 135  zebrafish
XP_004348174   98 VREMGPYVYN-ELRIKVNVTWN-----An---QT---V--LTYRQHQTYIFN----------QEMSGt-NT--E-D-DQI 148  Capsaspora ow...
GAA56005       87 LEEVGPYVYR-ERRERFDVQFG-----Ngs-eSH---T--VRFKYRIFYYFD----------RNKSI--ND--P-StVRI 139  Clonorchis si...
XP_003388574  120 IKEIGPFVYN-ESKTKYNLRWN-----Sd---ET---I--LEYFENTSYIFN----------KEKSNrlDP--S-H-VNI 171  Amphimedon qu...
XP_003387595   88 VNEVGPYSYR-EYRIKY---FNtsdllDg---DN---V--LQYTQRKTFHFS----------SSTSQ--NNtsE-T-DTI 141  Amphimedon qu...
CDJ01379       93 LRAVGPYVYR-RFIEKKDVRFR-----EdicgRG---L--MEYSTSTVYQFE----------PEGSI--GD--P-KkDRL 146  Echinococcus ...
XP_001747074  211 VNLIGPFNYL-EVRIKDNITWS-----Sd---ST---R--VSYTYKRAFTIIdtkcpsgvlyPNITC--SL--D-D-DMI 270  Monosiga brev...
CDS27098       72 LTVIGPYVYW-KEDEKLNISWT-----Sv---DD---SpaISYLKRTIYMFD----------PKLSS--GD--PkS-DKI 124  Hymenolepis m...
CDJ01817      118 LRTVGPYVYR-RITKKKGVRFS-----Ed---RCgrrV--LEYSLSTAYYFE----------RNGSI--GD--PgQ-DRL 171  Echinococcus ...
XP_011405711  120 VEEIGPFTYL-KEVTNEDEYWN-----K----DE---Tl-LSY---KRTILY----------TDDLS--VMdpY-S-TTV 168  Amphimedon qu...

Q6DHC7        136 -TSLNL---A---VAg----------VY-------RLI---G--------PKLADWL---------IRS--------S-- 161  zebrafish
XP_004348174  149 -TTINFglcG---LVg----------LL-------YTK---G--------LAVKMAIdg------lLQA--------Fp- 181  Capsaspora ow...
GAA56005      140 -TTPNL---Y---FLv----------MT-------SSN---M--------GWILG------------------------- 159  Clonorchis si...
XP_003388574  172 -TTINL---P---LIgfllqfeklinIS-------ATF---P--------PPINTIVkd------lIETiitelnkdF-- 218  Amphimedon qu...
XP_003387595  142 -CTINI---P---LVg----------AItqvlgleNKA---L--------RFLGKMLlk-----aeIII--------R-- 178  Amphimedon qu...
CDJ01379      147 -VVPNF---VeciANs----------MI-------KQA---G--------SFATQLLwg------fLSR----------- 177  Echinococcus ...
XP_001747074  271 mTTVNI---P---LMq----------IA-------SLY---A--------SFDNKFIkg------iLQN--------Fie 302  Monosiga brev...
CDS27098      125 -ISANL---P---ILa----------IS-------AANnagR--------GPSADTIel------iKFF--------T-- 156  Hymenolepis m...
CDJ01817      172 -LVPNFverI---ATs----------MI-------SQA---G--------STTTQWLwi-----------------lT-- 200  Echinococcus ...
XP_011405711  169 -TTINV---P---LLg----------LL-------KLL---EdiednpkyKEWKQVLddifrsgdwINE--------Ll- 212  Amphimedon qu...

Q6DHC7        162 ----------------------------GSSLFQNRTVKELLWGYKDPMLNS-----------------LV-----GAFY 191  zebrafish
XP_004348174  182 ----------------------------KEKYFMTRPVREILWGYKDPLMSAlhlvdn--------------tidpiIAL 219  Capsaspora ow...
GAA56005      160 ----------------------------DEGPFITLTAEEVMWGYTPALVSFlraf---------fgdkKV-----GLFA 197  Clonorchis si...
XP_003388574  219 ----------------------------NEKLIMTRPVSEILWGYEDPFLKFvadlla-----nvtfidLHkelngGFFQ 265  Amphimedon qu...
XP_003387595  179 ----------------------------GAKLYVCQPASALVFNYTDPLIQWlhssndlrrlglnlptdYV-----SL-- 223  Amphimedon qu...
CDJ01379      178 ------------------------------PLLLDLTVDEVMWGHEYK--NLltgkvl-----glvedtKI-----GLFK 215  Echinococcus ...
XP_001747074  303 fwrskyseglattnaasltaqllvldadSETLIIQRPVKEIIWGYTDPILANefdali--------------eevndYLR 368  Monosiga brev...
CDS27098      157 ----------------------------SPKVFTKQSVDAYLWGYEDTTLSLcktffp-----eickndRV-----GLLL 198  Hymenolepis m...
CDJ01817      201 ----------------------------PNPLLMNLTAEEIMWGHEYQSLSTakvfg-------mvkdtKI-----GLFN 240  Echinococcus ...
XP_011405711  213 ---------------------------dIePLFVSKTVDEILWGYEDPLFKLvheldpt--------------llpmanF 251  Amphimedon qu...

Q6DHC7        192 --PYNGTV--------------D-G--PY--T------VftGKDDINKVAIIERWQGET-SvnywnDSYC---------- 233  zebrafish
XP_004348174  220 --QQNDSAp-------------D-W--QFdsK------IltGKEDINQVVRYIQWDGFT-ElpywgSKYA---------- 264  Capsaspora ow...
GAA56005      198 --TNNGTN--------------V-N--EF--V------VntGAKNIQDIGKIYEVNGQQ-IldiwdNLEA---------- 239  Clonorchis si...
XP_003388574  266 --LEHQTD--------------TaG--PN--M------VytGKGSPQTTAQYLMYDGKT-SitgwgTPYA---------- 308  Amphimedon qu...
XP_003387595  224 --QKNNSA--------------D-DslPS--K------IytGHDDISKLGQFIQWNNLT-NlgiwpGDTA---------- 267  Amphimedon qu...
CDJ01379      216 --QLNNSV--------------K-G--PY--Q------IntGFYNISKLGKLVAIKGKT-HldnwnSTYA---------- 257  Echinococcus ...
XP_001747074  369 --KQNKTNfitplpsviqiqenD-P--SY--TktqrseIytGTDDINKVYTYTAWAGHEgSiglwkGTNCpnttlgrdyi 441  Monosiga brev...
CDS27098      199 --NSNNTM--------------K-G--PY--I------VdsGIKNSTNTGSFIAIKGNR-SlniwtTEKA---------- 240  Hymenolepis m...
CDJ01817      241 --RLNNTL--------------Y-G--PY--Q------IntGAHDISKLGALVAFEGKI-NldkwgSVYA---------- 282  Echinococcus ...
XP_011405711  252 slETREKV--------------Y-E--YN--V------IytGKNDSAIRSNFYIWNGMT-DisewgTATA---------- 295  Amphimedon qu...

Q6DHC7        234 ---DKINGS-------------DGSSFHPFLDKKEPLYFFSPDICRSISAEYEATVNL---KgIDVYR---YLL-PVDAL 290  zebrafish
XP_004348174  265 ---NMINGT-------------DASQFAPDVQDDFIAAVFVDSIYRSAYLLYHSDVSV---EgIRLKR---FTI-DPMLL 321  Capsaspora ow...
GAA56005      240 ---NMLNGT-------------DGTVAAPGLRVGSTVEFHVPDICRSVTSYAVDTTTTqerDdVEVTV---FSGsPPNST 300  Clonorchis si...
XP_003388574  309 ---QMINGT-------------EALLFHPGVSRTDVLDVYVDELFRSGYFTYYKDITE---FdIKMYQ---FRL-PQKEL 365  Amphimedon qu...
XP_003387595  268 ---NKINGT-------------EGLVFRPGLKEGDSLFAFVDDTVRSFPLEYNGSIDI---KgLPAFR---YAL-PMEVF 324  Amphimedon qu...
CDJ01379      258 ---NMLNGT-------------ADAITPPSVKLGDRRYLFSADLCRSVPLIAKKWVSA---KnLPELKllsLEM-DRKVF 317  Echinococcus ...
XP_001747074  442 kwaNAINGT-------------EALSFRPNLKEGDVINVFSDDIRRSSRLVYNNTLKT---KgIRTFR---FVI-DPLAL 501  Monosiga brev...
CDS27098      241 ---NAIHGTgrihfynplsstlDGFRLASGIQLSDPRDIFVTLLCQPITLKATNISHP---KaFSTL-----EV-AEMEL 308  Hymenolepis m...
CDJ01817      283 ---NMLNGS-------------ADAITPPSVKIGVRRHMFSSDLCRSVSFIAKKWVSA---SnYPRLKllaLEM-EEKIF 342  Echinococcus ...
XP_011405711  296 ---RMINGT-------------DAVVFHSNVSRNDTLTAFTDDFERSAYFSYESDEYI---YdLLSYR---FIL-PTEAL 352  Amphimedon qu...

Q6DHC7        291 A-SPVsnPDNMCYCTdheitRNCtlAGLLDITS-C--K------GT----PVFISLPHFL-YA--SIE-LQQGV--VGMN 350  zebrafish
XP_004348174  322 A-NSTvnPDNAAFYDfg-------pSGVLNMST----Aa-----GA----PVFASKPHFL-DG--DEI-YRTNV--LGLH 374  Capsaspora ow...
GAA56005      301 D-PLAk-wRTDMFCTk---dSGCppQGLLSLQR-CaaKk-----GAd--lPLFLSQPFFL-GA--DPQ-IAAAF--DGLP 361  Clonorchis si...
XP_003388574  366 Q-KAYq---dKGFYMdg-------pDGVLNLTAvF--Pl-----NV----PIFVSKPHFL-DA--DEY-YTNDI--NGPP 417  Amphimedon qu...
XP_003387595  325 D-SAFknEDNA---Rw---gSWCp-DGLIYLGV-I--Qt----pSV----PVFGSKARFL-DC--EPEqTRDQV--DGML 380  Amphimedon qu...
CDJ01379      318 L-SADeePDNAAFHPkvyptKKYppTGLLSISP-C--VdfgisgDE----PLFISLPFFN-QA--ADA-VKDAVvfEG-- 383  Echinococcus ...
XP_001747074  502 A-NASenEQMCAF-------NAYqpTGTLNMEE----Yv-----GG----PVYASKHHFL-DA--DPI-YLELV--DGIP 554  Monosiga brev...
CDS27098      309 DtDSTayEET--YCPikvsgPACppKGYYDISQ-C--Av-----SGdispPVFASFLHFMdNAtdDAF-IVHKV------ 371  Hymenolepis m...
CDJ01817      343 V-SADeePENVAFHPkvyptNQYppTGLLSLSP-C--VdfgiagDE----PLFISLPYFN-QA--TVE-VKEAVdfEG-- 408  Echinococcus ...
XP_011405711  353 N-TSNidP---GYYP-------NgpNGLYNVSA-I--Ep----fNA----PFFISKPHFL-DG--DPQ-LVTNI--TGLH 404  Amphimedon qu...

Q6DHC7        351 -PNLDE--HSIFLDVEPITGFTLRFSKRLQVNMMYGPSDDI-ALLNKIK-EHTIIPILWLNETAVLDDETAKMFKNELI- 424  zebrafish
XP_004348174  375 -PVREW--HDTNLDIEPITGALMQAAKRLQLNMEIRNDPYI-FRTGKTP-YAM-LPIFYGNESVCITADLAGQFKDQVY- 447  Capsaspora ow...
GAA56005      362 vPSKEK--YSTWVHIEPTTGFVLEAFKRIQFNIFMENTD---SKYKDMK-GPYYFPIAWIAEIAVADKKSVDMLANMVLa 435  Clonorchis si...
XP_003388574  418 -SNRDK--HDSFLNVEPITGAVLHAAKRLQINIQLKQYEDI-PDLSHLPiNTTYLPLLWVEETGSLNESIASTFRDTVY- 492  Amphimedon qu...
XP_003387595  381 vPHREM--HDTFINVHPTIGINIQFQRILQLNVQVNRTDEF-KELKNIN-GTIYYPVLYINEHAELTDDFKSYLMKNGL- 455  Amphimedon qu...
CDJ01379      384 -PTEPN--LMSHLHIDSKTGILLGGEFSFQINAFLAKD------IQKTP-EDIYFPLVYVKDVIHADRESAQKLYKAVH- 452  Echinococcus ...
XP_001747074  555 -P-PERllHDVTVDVEPHTGSTFEAHQRLQINVKMTRVPGL-ADYGNLTaAGFYLPVTKVDEHAIVTDDLVSQWQDQVG- 630  Monosiga brev...
CDS27098      372 --DQIR--DKFRLLAEPKTGIVVEAHVRLQVNVHLQRSPHMaDLFMNIS-DPMYLPIVWFVNDIEGSQEDLKRLHYALY- 445  Hymenolepis m...
CDJ01817      409 -PTEPN--LTSHLHIDPKTGILIEGELVYQINVFLAK------KIQKTP-KDIYFPLVYVKDITRAGGESAQQLHQMAY- 477  Echinococcus ...
XP_011405711  405 -PNKSV--HDSYLNVEPITGTTVKAAKKLQVNVEMKQREEF-IQLRYLK-ELTYYPLFYIVNVrns-------------- 465  Amphimedon qu...

Q6DHC7        425 ---SRM----DM-------LEGLQI----G----LLVTGSAIFLGCMI 450  zebrafish
XP_004348174  448 ---TPL----IA-------STAVHW----S----GIALGSIMLLVCIV 473  Capsaspora owczarzaki ATCC 30864
GAA56005      436 prkKVP----LI-------LTIVGA----I----STVLAVTLIVILVa 464  Clonorchis sinensis
XP_003388574  493 ---KPI----NT-------IQISAItvasV----SGSVGILLLLIFLM 522  Amphimedon queenslandica
XP_003387595  456 ---HQI----TV-------ATDVMY----GgyafLFVVAFIVLLAAVV 485  Amphimedon queenslandica
CDJ01379      453 ---ELPatirRA-------VRALIG----I----LVILAVSLLVAAVI 482  Echinococcus multilocularis
XP_001747074  631 ---LAL----EVrddaheaGIITGS----V----CLGISLIFLLAFIr 663  Monosiga brevicollis MX1
CDS27098      446 ---VSP----MR-------MHLVLL----I----FLISSLIMIVFLTI 471  Hymenolepis microstoma
CDJ01817      478 ---EFP----AV-------IHrtlqalvgvfeilavlllipvlilyrr 511  Echinococcus multilocularis
XP_011405711      ------------------------------------------------      Amphimedon queenslandica
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