Conserved Protein Domain Family
MAP7
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pfam05672: MAP7 (this model, PSSM-Id:283355 is obsolete and has been replaced by 461709)
MAP7 (E-MAP-115) family
The organization of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115/MAP7) has been identified as a microtubule-stabilizing protein predominantly expressed in cell lines of epithelial origin. The binding of this microtubule associated protein is nucleotide independent.
Links
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Statistics
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PSSM-Id: 283355
Aligned: 50 rows
Threshold Bit Score: 42.3924
Created: 15-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
A2AG50       433 EHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQE-EQERLEKEERER-LEKEELKRKAEEERLRIE-------MAYKRE 503 house mouse
XP_007249024 292 SPVTPTGKAGTTDAEEASRLLAERRRLARVQKEQE-EKQRME---EER-LRAEELQRKQAEERERQEq------AARQAE 360 Mexican tetra
XP_009295712 421 SPVTPTGKAGTTDAEEASRLLAERRRLARVLKEQE-EKQRLEDE---R-LRVEELQRQQEEERQRQEe------ENRLAE 489 zebrafish
XP_001922506 418 EESNSKAIAGTNSAAEASKILAENRRLAREQKEKE-EQLRIQKEEEEK-LRKEEEKRLAEEERLRRAe------EEKRLA 489 zebrafish
XP_006633052 397 EDSSTKAIAGTTSAEEAAKILAENRRLAREQKERE-EQQRLQREEEER-LRREEERQLAEQERARREe------EEKRLA 468 spotted gar
XP_006628068 243 VTPTGKPIAGTTDAEEASRLLAERRRQARLQRELE-ERQQREQEEAER-VRAEEERRKVAEERARQEe------EARRAE 314 spotted gar
XP_007506143 436 VEPSSKTGLETISAEETDKTLIEKQQSVPDQKDQE-EGGKDLKEEEER-KVKEETEKKAIEAEEERDaghtqlgETSPPE 513 gray short-tail...
XP_005803020 403 NAPTGKVGAGTTNAEEATRLLAERRRQARAQKELE-ERKQEKEQE-ER-LREEEQKKQLAQQLQGQQa------KVQQGE 473 southern platyfish
XP_004564067 417 APCTGKVAAGTSNAEEASRLLAERRRQARAQKELE-EKKREQQEE-EgrLPEE--RKQLAQEQQRQEp------VNQQVK 486 zebra mbuna
XP_008199436 425 EMTASVTKIRINTEEEAKAALAERRRLAREEAERQaEQERLRIEME----AQAELERQRREEE-----------QIQRLI 489 red flour beetle

A2AG50       504 QEkkrq-------eeeEKRKAEEKakekAEEELLSkekqekEKQEQ---EKkekamiekQKEAaEAKAQDAAKQMRLERE 573 house mouse
XP_007249024 361 EDrqrl-------eeeRRQKEVDD----RRQKERR------LKELQdqlDR--------EREEaFQRVQREAEKKQRERE 415 Mexican tetra
XP_009295712 490 EKrlrq-------eeqRCQREMED----RHQKEQR------WKELQddlER--------QREEaVQRVHREAERKRQERE 544 zebrafish
XP_001922506 490 EErkre-------eeeQTRLAEEE----KQQMELE------EQQRQaeqQK--------EREEaEAKAQEEAERQRQERA 544 zebrafish
XP_006633052 469 EEkkre-------eeeNARLAEEE----RARQELE------EQERQaelQQ--------QREEaEARAQEEAEKARQERE 523 spotted gar
XP_006628068 315 EErlre-------eeeQRLREEAE----RQQRERQ------ARELQarlDR--------EREEaEARAQQEAERLRQERE 369 spotted gar
XP_007506143 514 EQqqkt-------eedQERLAAEl-------------------------QQ--------QKEEaEVKAQEEAARQRRERE 553 gray short-tail...
XP_005803020 474 VRrnnvmdhhrlkleeDKRKEEQQ-----------------EVQIVa------------EKDKaKVQAKEDTERQRQGRE 524 southern platyfish
XP_004564067 487 ERgrreada-hlkqeeEKRKKEQQ-----------------EKELQaqmDR--------EREKaKVLAQEDVERQRQDRE 540 zebra mbuna
XP_008199436 490 EAqrla-------eqeRLEEAIREtkrrEEEERLR------REEEQ---RSk------lLKEEaERKAREEAEKKFAEQQ 547 red flour beetle

A2AG50       574 QIMLQIEQERLERKKRIDEIMKRTRKSDaSLEVKK 608 house mouse
XP_007249024 416 LLKLQEEQERLQRKKRIEEIMKRTRKTD-AEPKKD 449 Mexican tetra
XP_009295712 545 LLKIQEEQERLQRKKRIEEIMKRTRKPD-GEKKEE 578 zebrafish
XP_001922506 545 RIMQQNQQERMERKKRIEEIMKRTRKTD-QMDFKS 578 zebrafish
XP_006633052 524 RKLQQDQQERMERKKRIEEIMKRTRKTD-QNDSKR 557 spotted gar
XP_006628068 370 LQQLQMEQERLQRKKRIEEIMKRTRKSD-TFESKK 403 spotted gar
XP_007506143 554 RIMEQSVQERLERKKRIEEIMKRTRKVE-QNSEQS 587 gray short-tailed opossum
XP_005803020 525 QQTQQEEEERQLRKKRIEEIMKRTRKSEaDMKVl- 558 southern platyfish
XP_004564067 541 LQTQQEEEERQQRKKRIEEIMKRTRKgeaeskmee 575 zebra mbuna
XP_008199436 548 ERLKNEEKEREARRKRVEAIMRRTRGVN-NANspg 581 red flour beetle
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